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Intest Res > Volume 10(2); 2012 > Article
Intestinal Research 2012;10(2):189-195.
DOI: https://doi.org/10.5217/ir.2012.10.2.189    Published online April 30, 2012.
The Changes in Etiology and Clinical Features of Non-Traumatic Small Bowel Perforation
Byeong Gwan Kim, Ji Won Kim, Kook Lae Lee, Jae Kyung Lee, Ji Bong Jeong
Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Korea
비외상성 소장천공의 원인 질환 및 임상 양상의 변화
김병관, 김지원, 이국래, 이재경, 정지봉
서울대학교 보라매병원 내과, 서울대학교 의과대학 내과학교실
Abstract
Background/Aims
We investigated the clinical features, and treatment outcomes in patients with non-traumatic small bowel perforations and compared these results to the previous study with patients who were diagnosed between 1997 and 2002. Methods: Patients who diagnosed non-traumatic small bowel perforation between January 2003 and December 2008 were reviewed retrospectively. Results: Of 38 patients of non-traumatic small bowel perforation, the most common etiologies were Crohn's disease (CD) (36.8%), followed by intestinal tuberculosis (ITB) (28.9%) and primary malignancy (15.8%). In the study of 2002, however, the most common etiologies were idiopathic (39.3%), followed by mechanical obstruction (28.6%) and infectious enteritis (14.3%). Of 38 cases, 8 perforation sites were found in the jejunum and 30 in the ileum. The number of perforations was single in 20, two in 15, and over 2 in 3 cases. Twenty-five patients were treated with resection and anastomosis, nine patients with primary closure, and four patients with both procedures. The site and number of perforations, surgical methods, and post-operative complication rates were similar to those of 2002. The perforation patients with ITB had more frequent night sweats and pulmonary tuberculosis findings than those with CD. Conclusions: Although the clinical features and surgical outcomes in the 2009 study were similar to those of the previous study conducted in 2003, the etiologies of perforations were different; CD and ITB were two most common etiologies. In addition, clinical characteristics such as night sweats or pulmonary tuberculosis were suggestive findings for the diagnosis of ITB. (Intest Res 2012;10: 0-195)
Key Words: Intestinal Perforation, Tuberculosis, Gastrointestinal, Crohn Disease
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