- Miscellaneous
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Bloating in a supine position
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Akira Hokama, Yasuka Nakada, Aki Yanagida, Erika Koga, Kunikazu Hoshino, Jiro Fujita
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Intest Res 2021;19(2):252-253. Published online June 18, 2020
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DOI: https://doi.org/10.5217/ir.2020.00019
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- Inflammatory bowel diseases
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Sausage-like fingers in Crohn’s disease
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Akira Hokama, Taiga Miyagi, Yukiko Takeichi, Eriko Uema, Sayuri Takehara, Tetsuya Ohira, Atsushi Iraha, Tetsu Kinjo, Jiro Fujita
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Intest Res 2020;18(3):341-342. Published online May 25, 2020
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DOI: https://doi.org/10.5217/ir.2020.00036
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- IBD
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Stroke and neck bruit in a boy with Crohn’s disease
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Ryosaku Tomiyama, Akira Hokama, Erika Koga, Kohei Shimabukuro, Yuiko Oishi, Tetsuya Ohira, Atsushi Iraha, Tetsu Kinjo, Jiro Fujita
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Intest Res 2019;17(4):565-566. Published online April 15, 2019
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DOI: https://doi.org/10.5217/ir.2019.00019
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- IBD
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A pulmonary nodule in a patient with Crohn’s disease
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Akira Hokama, Shusaku Haranaga, Takanobu Sasaki, Hirofumi Matsumoto, Tetsuya Ohira, Atsushi Iraha, Tetsu Kinjo, Saifun Nahar, Jiro Fujita
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Intest Res 2019;17(3):438-439. Published online February 11, 2019
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DOI: https://doi.org/10.5217/ir.2019.00010
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- IBD
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Distribution of cytomegalovirus genotypes among ulcerative colitis patients in Okinawa, Japan
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Saifun Nahar, Akira Hokama, Atsushi Iraha, Tetsuya Ohira, Tetsu Kinjo, Tetsuo Hirata, Takeshi Kinjo, Gretchen L. Parrott, Jiro Fujita
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Intest Res 2018;16(1):90-98. Published online January 18, 2018
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DOI: https://doi.org/10.5217/ir.2018.16.1.90
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Abstract
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- Background/Aims
To determine the prevalence of glycoprotein B (gB), glycoprotein N (gN), and glycoprotein H (gH) genotypes of human cytomegalovirus (HCMV) superimposed on ulcerative colitis (UC) patients in Japan. MethodsFour archived stool samples and 7-archived extracted DNA from stool samples of 11 UC patients with positive multiplex polymerase chain reaction (PCR) results for HCMV were used UL55 gene encoding gB, UL73 gene encoding gN, and UL75 gene encoding gH were identified by PCR. Genotypes of gB and glycoprotein N were determined by sequencing. ResultsAmong 11 samples, 8 samples were amplified through PCR. gB, gN, and gH genotypes were successfully detected in 3 of 8 (37.5%), 4 of 8 (50%), and 8 of 8 (100%), respectively. The distribution of gB and gN genotypes analyzed through phylogenetic analysis were as follows: gB1 (2/3, 66.7%), gB3 (1/3, 33.3%), gN3a (2/4, 50%), and gN3b (2/4, 50%). Other gB genotypes (gB2 and gB4) and gN genotypes (gN1, gN2, and gN4) were not detected in this study. Out of successfully amplified 8 samples of gH genotype, gH1 and gH2 were distributed in 12.5% and 75% samples, respectively. Only 1 sample revealed mixed infection of gH genotype. The distribution of gH1 and gH2 differed significantly (1:6, P<0.05) in UC patients. The distribution of single gH genotype also revealed significant difference in UC patients who were treated with immunosuppressive drug (P<0.05). ConclusionsIn this study, gB1, gN3, and gH2 gene were determined as the most frequently observed genotypes in UC patients, which suggest that there might be an association between these genotypes of HCMV and UC.
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Citations
Citations to this article as recorded by 
- Significance of Cytomegalovirus gB Genotypes in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation: Insights from a Single-Centre Investigation
Tamara Vasiljevic, Marko Jankovic, Ana Tomic, Ida Bakrac, Stefan Radenovic, Danijela Miljanovic, Aleksandra Knezevic, Tanja Jovanovic, Irena Djunic, Milena Todorovic-Balint Pharmaceuticals.2024; 17(4): 428. CrossRef - Cytomegalovirus Genotype Distribution among Congenital and Perinatal Infected Patients with CMV-Associated Thrombocytopenia
Hongbo Hu, Wenwen Peng, Qiaoying Peng, Ying Cheng Fetal and Pediatric Pathology.2022; 41(1): 77. CrossRef - Cytomegalovirus Genotype and Virulence in Infants with Congenital Infection
Hong-bo Hu, Jian-gang Wu, Jian-jun Sun, Qiao-ying Peng, Xiao-peng Shang Journal of Pediatric Infectious Diseases.2021; 16(04): 171. CrossRef - Common Polymorphisms in the Glycoproteins of Human Cytomegalovirus and Associated Strain-Specific Immunity
Hsuan-Yuan Wang, Sarah M. Valencia, Susanne P. Pfeifer, Jeffrey D. Jensen, Timothy F. Kowalik, Sallie R. Permar Viruses.2021; 13(6): 1106. CrossRef - Cytomegalovirus and Inflammatory Bowel Diseases (IBD) with a Special Focus on the Link with Ulcerative Colitis (UC)
Alexandre Jentzer, Pauline Veyrard, Xavier Roblin, Pierre Saint-Sardos, Nicolas Rochereau, Stéphane Paul, Thomas Bourlet, Bruno Pozzetto, Sylvie Pillet Microorganisms.2020; 8(7): 1078. CrossRef
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