Intestinal Research

Nilesh Pandav

2 Articles

The role of capsule endoscopy in etiological diagnosis and management of obscure gastrointestinal bleeding: Vikas Pandey, Meghraj Ingle, Nilesh Pandav, Pathik Parikh, Jignesh Patel, Aniruddha Phadke, Prabha Sawant; Intest Res 2016;14(1):69-74. Published online January 26, 2016; DOI: https://doi.org/10.5217/ir.2016.14.1.69

Background/Aims

To investigate the various etiologies, yields, and effects of capsule endoscopy (CE) on management and complications, along with follow up of patients with obscure gastrointestinal (GI) bleeding.

Methods

The study group of patients included those having obscure, overt, or occult GI bleeding. The findings were categorized as (A) obvious/definitive, (B) equivocal, or (C) negative. Any significant alteration in patient management post CE in the form of drug or surgical intervention was noted.

Results

Total patients included in the study were 68 (48 males and 20 females). The ratio of male:female was 2.4:1. The age ranged between 16 years to 77 years. Mean age for males was 62±14 years, for females 58±16 years. The total yield of CE with definitive lesions was in 44/68 (65.0%) of patients. In descending order (A) angiodysplasia 16/68 (23.53%), (B) Crohn's disease 10/68 (14.70%), (C) non-steroidal anti-inflammatory drug enteropathy 8/68 (11.76%), (D) small bowel ulcers 4/68 (5.88%), (E) jejunal and ileal polyps 2/68 (2.94%), (F) intestinal lymphangiectasis 2/68 (2.94%), and (G) ileal hemangiomas 2/68 (2.94%) were followed. Equivocal findings 12/68 (17.65%) and negative study 12/68 (17.65%) was found. Complications in the form of capsule retention in the distal ileum were noted in 2/68 (2.94%) subjects. Statistically, there was a higher probability of finding the etiology if the CE was done during an episode of bleeding.

Conclusions

CE plays an important role in diagnosing etiologies of obscure GI bleeding. Its role in influencing the management outcome is vital.

Citations

Citations to this article as recorded by

Capsule endoscopy for obscure gastrointestinal bleed in the tropics: A single-center experience on 350 patients
Uday C. Ghoshal, Piyush Mishra, Akash Mathur, Sai Prathap Reddy, Bushra Fatima, Asha Misra
Indian Journal of Gastroenterology.2024; 43(5): 1045. CrossRef
Capsule endoscopy for small bowel bleed: Current update
Uday C. Ghoshal, Akash Roy, Mahesh K. Goenka
Indian Journal of Gastroenterology.2024; 43(5): 896. CrossRef
An intelligent intestinal bleeding diagnosis and treatment capsule system based on color recognition
Panpan Qiao, Luo Yu, Hongying Liu, Xueping Yan, Xitian Pi
Biomedical Microdevices.2023;[Epub] CrossRef
Systematic review and meta‐analysis of the diagnostic and therapeutic yield of small bowel endoscopy in patients with overt small bowel bleeding
Genta Uchida, Masanao Nakamura, Takeshi Yamamura, Kazuhiro Furukawa, Hiroki Kawashima, Takashi Honda, Masatoshi Ishigami, Mitsuhiro Fujishiro
Digestive Endoscopy.2021; 33(1): 66. CrossRef
Comparison in the Diagnostic Yield between “Pillcam SB3” Capsule Endoscopy and “OMOM Smart Capsule 2” in Small Bowel Bleeding: A Randomized Head-to-Head Study
Gerardo Blanco-Velasco, Raúl Antonio Zamarripa-Mottú, Omar Michel Solórzano-Pineda, Miguel Mascarenhas-Saraiva, Juan Manuel Blancas-Valencia, Oscar Victor Hernández-Mondragón
Digestive Diseases.2021; 39(3): 211. CrossRef
Heterotopia de mucosa gástrica en intestino delgado, hallazgo en videocápsula endoscópica. Reporte de caso
Santiago Castaño, Natalia Calvache, Mauricio Sepúlveda
Revista Colombiana de Gastroenterología.2019; 34(3): 314. CrossRef
Meta-analysis shows similar re-bleeding rates among Western and Eastern populations after index video capsule endoscopy
Georgios Tziatzios, Paraskevas Gkolfakis, Cesare Hassan, Ervin Toth, Angelo Zullo, Anastasios Koulaouzidis, George D. Dimitriadis, Konstantinos Triantafyllou
Digestive and Liver Disease.2018; 50(3): 226. CrossRef
Lanreotide in the management of small bowel angioectasias: seven-year data from a tertiary centre
S. Chetcuti Zammit, D. S. Sanders, R. Sidhu
Scandinavian Journal of Gastroenterology.2017; : 1. CrossRef
Role of capsule endoscopy in suspected or established Crohn's disease in real practice
Hyun Joo Jang
Intestinal Research.2017; 15(4): 431. CrossRef
The Role of Dynamic Contrast-enhanced Multidetector-row Computed Tomography in Diagnosis of Obscure Gastrointestinal Bleeding
Jee Hyun Kim, Jong Pil Im
The Korean Journal of Gastroenterology.2016; 67(4): 165. CrossRef

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Spectrum of chronic small bowel diarrhea with malabsorption in Indian subcontinent: is the trend really changing?: Nirav Pipaliya, Meghraj Ingle, Chetan Rathi, Prateik Poddar, Nilesh Pandav, Prabha Sawant; Intest Res 2016;14(1):75-82. Published online January 26, 2016; DOI: https://doi.org/10.5217/ir.2016.14.1.75

Abstract PDF PubReader ePub

Background/Aims

This study aimed to document the recent etiological spectrum of chronic diarrhea with malabsorption and also to compare features that differentiate tropical sprue from parasitic infections, the two most common etiologies of malabsorption in the tropics.

Methods

We analyzed 203 consecutive patients with malabsorption. The etiological spectrum and factors that differentiated tropical sprue from parasitic infections were analyzed.

Results

The most common etiology was tropical sprue (n=98, 48.3%) followed by parasitic infections (n=25, 12.3%) and tuberculosis (n=22, 10.8%). Other causes were immunodeficiency (n=15, 7.3%; 12 with human immunodeficiency virus and 3 with hypogammaglobulinemia), celiac disease (n=11, 5.4%), Crohn's disease (n=11, 5.4%), small intestinal bacterial overgrowth (n=11, 5.4%), hyperthyroidism (n=4, 1.9%), diabetic diarrhea (n=4, 1.9%), systemic lupus erythematosus (n=3, 1.4%), metastatic carcinoid (n=1, 0.5%) and Burkitt's lymphoma (n=1, 0.5%). On multivariate analysis, features that best differentiated tropical sprue from parasitic infections were larger stool volume (P=0.009), severe weight loss (P=0.02), knuckle hyperpigmentation (P=0.008), low serum B12 levels (P=0.05), high mean corpuscular volume (P=0.003), reduced height or scalloping of the duodenal folds on endoscopy (P=0.003) and villous atrophy on histology (P=0.04). Presence of upper gastrointestinal (GI) symptoms like bloating, nausea and vomiting predicted parasitic infections (P=0.01).

Conclusions

Tropical sprue and parasitic infections still dominate the spectrum of malabsorption in India. Severe symptoms and florid malabsorption indicate tropical sprue while the presence of upper GI symptoms indicates parasitic infections.

Citations

Citations to this article as recorded by

The etiological profile of chronic organic non-bloody diarrhea in India: Emergence of inflammatory bowel disease as a dominant cause
Prachi Daga, Amarender Singh Puri, Lipika Lipi, Sumit Bhatia, Randhir Sud
Indian Journal of Gastroenterology.2025; 44(2): 181. CrossRef
Inflammatory Bowel Disease in Children
Asha Jois, George Alex
Indian Journal of Pediatrics.2024; 91(5): 490. CrossRef
The etiological profile of chronic organic non-bloody diarrhea in India: A closer look
Uday C. Ghoshal, Subhamoy Das, Mahesh K. Goenka
Indian Journal of Gastroenterology.2024;[Epub] CrossRef
Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia
Alaullah Sheikh, Brunda Tumala, Tim J. Vickers, John C. Martin, Bruce A. Rosa, Subrata Sabui, Supratim Basu, Rita D. Simoes, Makedonka Mitreva, Chad Storer, Erik Tyksen, Richard D. Head, Wandy Beatty, Hamid M. Said, James M. Fleckenstein
Nature Communications.2022;[Epub] CrossRef
Acute Bacterial Gastroenteritis
James M. Fleckenstein, F. Matthew Kuhlmann, Alaullah Sheikh
Gastroenterology Clinics of North America.2021; 50(2): 283. CrossRef
Clinical, endoscopic, and histological differentiation between celiac disease and tropical sprue: A systematic review
Pragya Sharma, Vandana Baloda, Gaurav PS Gahlot, Alka Singh, Ritu Mehta, Sreenivas Vishnubathla, Kulwant Kapoor, Vineet Ahuja, Siddhartha Datta Gupta, Govind K Makharia, Prasenjit Das
Journal of Gastroenterology and Hepatology.2019; 34(1): 74. CrossRef
What makes non-cirrhotic portal hypertension a common disease in India? Analysis for environmental factors
Ashish Goel, Banumathi Ramakrishna, Uday Zachariah, K.G. Sajith, Deepak K. Burad, Thomas A. Kodiatte, Shyamkumar N. Keshava, K.A. Balasubramanian, Elwyn Elias, C.E. Eapen
Indian Journal of Medical Research.2019; 149(4): 468. CrossRef
Nutritional Approach in Tropical Sprue Patients
Stefanie Knebusch Toriello
Current Tropical Medicine Reports.2018; 5(3): 211. CrossRef

10,974 View
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