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Seung Woon Paik 3 Articles
Acute Diarrhea after Bone Marrow Transplantation
Hyun Joo Suh, Young Ho Kim, Ji Hyang Kim, Yong Sung Choi, Jeong Kim, Poong Lyul Rhee, Jae J. Kim, Seung Woon Paik, Jong Chul Rhee
Intest Res 2005;3(2):104-109.   Published online December 30, 2005
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Background/Aims
A few study have performed the cause of acute diarrhea in patients undergoing bone marrow transplantation (BMT) so far. We analyzed the prevalence of acute diarrhea after BMT, its etiology and its risk factors. Methods: We retrospectively evaluated records of 132 patients undergoing BMT between September 1999 and Jun 2003. Diarrhea had to get its onset from day of admission to day of 100 posttransplant. Results: 95 patients developed acute diarrhea in 132 patients (72% of incidence). The total episodes of diarrhea were 117. Infection was found in 16 of 117 episodes (13.7%). Acute Graft versus host disease was responsible for 9 of 117 episodes (10.3%). Possible etiology of diarrhea was composed of 19 episodes of medication-induced diarrhea (16.2%), 11 episodes of mucositis (9.4%) and 5 episodes of infection (4.3%). Unknown originated diarrhea were 56 episodes (47.9%). Development of diarrhea was not significantly associated with age, sex, underlying disease, BMT conditions and prophylaxis of CMV virus. Conclusions: Acute diarrhea was common in patients undergoing BMT. However, etiology have not clearly evaluated in half of the cases. Further tests to evaluate etiology of acute diarrhea should be investigated. (Intest Res 2005;3:104-109)
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A Case of Mesenteric Vasculitis Induced by Norpal Cactus Extract
Jung Su Ha, Dong Kyung Chang, Jun Haeng Lee, Young Ho Kim, Hee Jung Son, Poong Lyul Rhee, Jae J. Kim, Seung Woon Paik, Jong Chul Rhee
Intest Res 2005;3(1):85-88.   Published online June 30, 2005
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Herbs are inadvertently regarded safe and harmless because of their natural origin and the experience of long-term use as a folk medicine. However, some herbal medicines are associated with toxicities in the organs such as liver, kidney, skin, or heart. Norpal cactus extract is a kind of herbs which is used for ordinary food in Mexico, and has effects on hypergylcemia and hypercholesterolemia, and inflammation. There has been no particular reports of drug-induced vasculitis by herbal medicine. Here, we present a case of vasculitis that was initially manifestated as acute diarrhea and abdominal pain after ingestion of Norpal cactus extract. (Intest Res 2005;3:85-89)
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The Different Colonoscopic Manifestations of Primary Colorectal Lymphomas by Their Cellular Origin
Won Hyeok Choe, Young-Ho Kim, Beom Jin Kim, Jae Uk Lee, Jun Haeng Lee, Hee Jung Son, Poong-Lyul Rhee, Jae J. Kim, Seung Woon Paik, Jong Chul Rhee, Young Hyeh Ko, Woo Yong Lee, Ho kyung Chun
Intest Res 2003;1(1):22-30.   Published online May 27, 2003
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Background/Aims
There were few reports of primary colorectal lymphoma mainly focusing on the colonoscopic findings. The aim of this study was to review the colonoscopic findings and clinical characteristics of primary colorectal lymphomas by their cellular origin. Methods: Clinical information was retrospectively obtained from 18 cases with primary colorectal lymphoma from January 1994 to December 2001. The extent of disease was defined as focal or diffuse. Colonoscopic images were reviewed and classified into superficial, ulcerative, ulceroinfiltrative, and fungating types. Results: The study included thirteen men and five women, with a mean age of 48.6±13.3 years at disease onset. The most common presenting symptom was abdominal pain and the most frequent involvement was cecum. The endoscopic type was fungating in 6 cases, ulceroinfiltrative in 5 cases, ulcerative in 5 cases, and superficial in 2 cases. The lymphomas were B-cell lineage in 13 cases and T-cell lineage in 5 cases. Between B-cell and T-cell lymphomas, there was no statistically significant difference in age, gender, and the stage of the disease. All B-cell lymphomas were focally located, whereas 80% of T-cell lymphomas were diffuse (p=0.002). T-cell lymphomas were classified as ulcerative type in four cases and superficial type in one case. On the other hand, the most common colonoscopic feature of primary B-cell colorectal lymphoma was the fungating type (p=0.009). Conclusions: We found that primary colorectal lymphomas have different colonoscopic features by their cellular origin. (Intestinal Research 2003;1:22-30)
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