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Stefano Fusco 1 Article
Inflammatory Bowel Diseases
Quality of life in inflammatory bowel diseases: it is not all about the bowel
Ronald Keller, Nazar Mazurak, Laura Fantasia, Stefano Fusco, Nisar P Malek, Jan Wehkamp, Paul Enck, Thomas Klag
Intest Res 2021;19(1):45-52.   Published online February 27, 2020
DOI: https://doi.org/10.5217/ir.2019.00135
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background/Aims
The inflammatory bowel diseases (IBD), ulcerative colitis (UC), and Crohn’s disease (CD) are chronic diseases mostly affecting young patients. As they are diseases accompanying patients for their entire life, and the quality of life (QUOL) interacts with disease activity, improving QUOL should be one of the main goals of therapy. This study aims to identify factors contributing to good or impaired QUOL.
Methods
Questionnaires addressing health-related QUOL and other psychological and social features were positioned on our institutions’ webpage and on the webpage of the largest self-help group for IBD in Germany. Patients were subdivided according to their QUOL score with a cutoff of <60. We used the Short Inflammatory Bowel Disease Questionnaire, the Assessment of the Demand for Additional Psychological Treatment, and the Fear of Progression Questionnaire Short Form.
Results
High numbers of patients in both subgroups showed an impaired QUOL (87.34% in UC, 91.08% in CD). Active extraintestinal manifestations, smoking, high fear of progression and high demand for psychotherapy were associated with reduced QUOL. In addition, polypharmacological interventions did not result in a good QUOL, but ostomies are linked to improved QUOL especially in CD patients.
Conclusions
Scores used in clinical day-to-day-practice mainly focusing on somatic factors do not sufficiently address important aspects concerning QUOL. Most importantly, extraintestinal manifestations show a hitherto underestimated impact on QUOL.

Citations

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    Journal of Crohn's and Colitis.2024; 18(6): 851.     CrossRef
  • The association between fear of progression and medical coping strategies among people living with HIV: a cross-sectional study
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    Nutrients.2024; 16(12): 1826.     CrossRef
  • Development and Assessment of a Novel Ulcerative Colitis–Specific Quality of Life Questionnaire: A Prospective, Multi-Institutional Study
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    Yonsei Medical Journal.2024; 65(11): 636.     CrossRef
  • Comprehensive analysis of psychological symptoms and quality of life in early patients with IBD: a multicenter study from China
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    Nutrition Reviews.2024;[Epub]     CrossRef
  • Self-perception and adjustment to Crohn's disease in emerging and young adults: The clinical and psychosocial associated factors
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    Pratiques Psychologiques.2024;[Epub]     CrossRef
  • Potential of Gut Microbe-Derived Extracellular Vesicles to Differentiate Inflammatory Bowel Disease Patients from Healthy Controls
    Min Heo, Young Soo Park, Hyuk Yoon, Nam-Eun Kim, Kangjin Kim, Cheol Min Shin, Nayoung Kim, Dong Ho Lee
    Gut and Liver.2023; 17(1): 108.     CrossRef
  • Obesity and novel management of inflammatory bowel disease
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    World Journal of Gastroenterology.2023; 29(12): 1779.     CrossRef
  • A Holistic Perspective on How Photobiomodulation May Influence Fatigue, Pain, and Depression in Inflammatory Bowel Disease: Beyond Molecular Mechanisms
    E-Liisa Laakso, Tatjana Ewais
    Biomedicines.2023; 11(5): 1497.     CrossRef
  • Psychoemotional disorders of patients with inflammatory bowel diseases: prevalence, pathogenesis and treatment options
    Igor G. Bakulin, Venera Sh. Stamboltsyan, Inna A. Oganezova
    Russian Family Doctor.2023; 27(2): 23.     CrossRef
  • CE: Nursing Care for Patients After Ostomy Surgery
    Heidi H. Cross
    AJN, American Journal of Nursing.2023; 123(8): 34.     CrossRef
  • Efficacy and Safety of Infliximab in Intestinal Behçet’s Disease: A Multicenter, Phase 3 Study (BEGIN)
    Jae Hee Cheon, Hyun-Soo Kim, Dong Soo Han, Sung Kook Kim, Sung Jae Shin, Joo Sung Kim, Byong Duk Ye, Geun Am Song, YoungJa Lee, Youngdoe Kim, Yoosun Lee, Won Ho Kim
    Gut and Liver.2023; 17(5): 777.     CrossRef
  • Validity and reliability of the Indonesian version of the 9-item Inflammatory Bowel Disease Questionnaire (IBDQ-9)
    Dekta Filantropi Esa, Hamzah Shatri, Cleopas Martin Rumende, Adityo Susilo, Hasan Maulahela, Achmad Fauzi, Marcellus Simadibrata
    Medical Journal of Indonesia.2023; 32(3): 168.     CrossRef
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    Seok-Young Kim, Seung Yong Shin, Maham Saeed, Ji Eun Ryu, Jung-Seop Kim, Junyoung Ahn, Youngmi Jung, Jung Min Moon, Chang Hwan Choi, Hyung-Kyoon Choi
    Metabolites.2023; 14(1): 2.     CrossRef
  • Apex Score: Predicting Flares in Small-Bowel Crohn’s Disease After Mucosal Healing
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    Digestive Diseases and Sciences.2022; 67(4): 1278.     CrossRef
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    Italian Journal of Dermatology and Venereology.2022;[Epub]     CrossRef
  • Correlation of fecal calprotectin and patient-reported outcome measures in patients with ulcerative colitis
    Nagesh Kamat, Sudheer K Vuyyuru, Saurabh Kedia, Pabitra Sahu, Bhaskar Kante, Peeyush Kumar, Mukesh Kumar Ranjan, Mukesh Kumar Singh, Sambuddha Kumar, Vikas Sachdev, Govind Makharia, Vineet Ahuja
    Intestinal Research.2022; 20(2): 269.     CrossRef
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    Journal of Clinical Medicine.2022; 11(11): 3034.     CrossRef
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    World Journal of Clinical Cases.2021; 9(36): 11285.     CrossRef
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    Journal of Clinical Medicine.2020; 9(8): 2416.     CrossRef
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