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Volume 13(1); January 2015
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Perspective
Intestinal Research Is Now Registered in PubMed Central
Suk-Kyun Yang
Intest Res 2015;13(1):1-1.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.1
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Editorials
A Clinical Significance of Assessing Cytomegalovirus Infection Status in Patients With Ulcerative Colitis
Sooyun Chang, Jae Hee Cheon
Intest Res 2015;13(1):2-3.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.2
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Citations

Citations to this article as recorded by  
  • A quick guide to diagnosis and treatment of cytomegalovirus infection in the gut: current dilemmas
    Iļja Drjagunovs, Sniedze Laivacuma, Indra Zeltiņa, Aleksejs Derovs
    Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences..2022; 76(5-6): 585.     CrossRef
  • Approach to cytomegalovirus infections in patients with ulcerative colitis
    Sung Chul Park, Yoon Mi Jeen, Yoon Tae Jeen
    The Korean Journal of Internal Medicine.2017; 32(3): 383.     CrossRef
  • Author's Reply
    Jaeyoung Chun, Jong Pil Im
    Intestinal Research.2015; 13(2): 184.     CrossRef
  • 4,173 View
  • 53 Download
  • 3 Web of Science
  • 3 Crossref
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The Positive Influences of Increasing Age at Diagnosis of Inflammatory Bowel Disease on Disease Prognostication in Asian Perspective
Raja Affendi Raja Ali
Intest Res 2015;13(1):4-5.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.4
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  • A four-decade analysis of the incidence trends, sociodemographic and clinical characteristics of inflammatory bowel disease patients at single tertiary centre, Kuala Lumpur, Malaysia
    Norfilza Mohd Mokhtar, Khairul Najmi Muhammad Nawawi, Jaarvis Verasingam, Wong Zhiqin, Ismail Sagap, Zairul Azwan Mohd Azman, Luqman Mazlan, Hamzaini Abdul Hamid, Nur Yazmin Yaacob, Isa Mohamed Rose, Eden Low Ngah Den, Mah Suit Wan, Raja Affendi Raja Ali
    BMC Public Health.2019;[Epub]     CrossRef
  • Delineating inflammatory bowel disease through transcriptomic studies: current review of progress and evidence
    Seow-Neng Chan, Eden Ngah Den Low, Raja Affendi Raja Ali, Norfilza Mohd Mokhtar
    Intestinal Research.2018; 16(3): 374.     CrossRef
  • Can narrow-band imaging of Peyer's patches predict the recurrence of ulcerative colitis?
    Yoon Jae Kim
    Intestinal Research.2016; 14(4): 295.     CrossRef
  • Inflammatory Bowel Disease Cohort Studies in Korea: Present and Future
    Jung Won Lee, Jong Pil Im, Jae Hee Cheon, You Sun Kim, Joo Sung Kim, Dong Soo Han
    Intestinal Research.2015; 13(3): 213.     CrossRef
  • 4,119 View
  • 33 Download
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Statement
Seminar Report From the 2014 Taiwan Society of Inflammatory Bowel Disease (TSIBD) Spring Forum (May 24th, 2014): Crohn's Disease Versus Intestinal Tuberculosis Infection
Meng-Tzu Weng, Shu-Chen Wei, Chun-Che Lin, Yuk-Min Tsang, Chia-Tung Shun, Jann-Yuan Wang, Ming-Jium Shieh, Cheng-Yi Wang, Jau-Min Wong
Intest Res 2015;13(1):6-10.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.6
AbstractAbstract PDFPubReader

Since Taiwan is an endemic area for tuberculosis (TB), differential diagnosis between the intestinal TB and Crohn's disease is an important issue. The steering committee of Taiwan Society of Inflammatory Bowel Disease (TSIBD) has arranged a seminar accordingly on May 24th, 2014 and the different point of views by gastroenterologist, radiologist, pathologist and infectious disease specialist were suggested to help the proper diagnosis and management of these two diseases.

Citations

Citations to this article as recorded by  
  • Intestinal tuberculosis with small bowel stricture and hemorrhage as the predominant manifestation: Three case reports
    Gang Huang, Kang-Kang Wu, Xiao-Na Li, Jing-Hua Kuai, Ai-Jun Zhang
    World Journal of Gastrointestinal Surgery.2024; 16(1): 248.     CrossRef
  • Management of Crohn’s disease in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease updated in 2023
    Jia-Feng Wu, Hsu-Heng Yen, Horng-Yuan Wang, Ting-An Chang, Chung-Hsin Chang, Chen-Wang Chang, Te-Hsin Chao, Jen-Wei Chou, Yenn-Hwei Chou, Chiao-Hsiung Chuang, Wen-Hung Hsu, Tzu-Chi Hsu, Tien-Yu Huang, Tsung-I Hung, Puo-Hsien Le, Chun-Che Lin, Chun-Chi Lin
    Intestinal Research.2024; 22(3): 250.     CrossRef
  • Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease updated in 2023
    Hsu-Heng Yen, Jia-Feng Wu, Horng-Yuan Wang, Ting-An Chang, Chung-Hsin Chang, Chen-Wang Chang, Te-Hsin Chao, Jen-Wei Chou, Yenn-Hwei Chou, Chiao-Hsiung Chuang, Wen-Hung Hsu, Tzu-Chi Hsu, Tien-Yu Huang, Tsung-I Hung, Puo-Hsien Le, Chun-Che Lin, Chun-Chi Lin
    Intestinal Research.2024; 22(3): 213.     CrossRef
  • Clinical characteristics and diagnosis of intestinal tuberculosis in clinical practice at Thailand’s largest national tertiary referral center: An 11-year retrospective review
    Asawin Sudcharoen, Gahwin Ruchikajorndech, Sitthipong Srisajjakul, Ananya Pongpaibul, Popchai Ngamskulrungroj, Orawan Tulyaprawat, Julajak Limsrivilai, Mao-Shui Wang
    PLOS ONE.2023; 18(4): e0282392.     CrossRef
  • Clinical features and treatment of inflammatory bowel disease in a low-incidence area
    Hsu-Heng Yen, Tsui-Chun Hsu, Mei-Wen Chen, Pei-Yuan Su, Yang-Yuan Chen
    Medicine.2021; 100(10): e25090.     CrossRef
  • Biologics for the Management of Inflammatory Bowel Disease: A Review in Tuberculosis-Endemic Countries
    Rupa Banerjee, Raja Affendi Raja Ali, Shu Chen Wei, Shashi Adsul
    Gut and Liver.2020; 14(6): 685.     CrossRef
  • Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia
    Choon Jin Ooi, Ida Hilmi, Rupa Banerjee, Sai Wei Chuah, Siew Chien Ng, Shu Chen Wei, Govind K Makharia, Pises Pisespongsa, Min Hu Chen, Zhi Hua Ran, Byong Duk Ye, Dong Il Park, Khoon Lin Ling, David Ong, Vineet Ahuja, Khean Lee Goh, Jose Sollano, Wee Chia
    Journal of Gastroenterology and Hepatology.2019; 34(8): 1296.     CrossRef
  • Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn’s disease in Asia
    Choon Jin Ooi, Ida Hilmi, Rupa Banerjee, Sai Wei Chuah, Siew Chien Ng, Shu Chen Wei, Govind K Makharia, Pises Pisespongsa, Min Hu Chen, Zhi Hua Ran, Byong Duk Ye, Dong Il Park, Khoon Lin Ling, David Ong, Vineet Ahuja, Khean Lee Goh, Jose Sollano, Wee Chia
    Intestinal Research.2019; 17(3): 285.     CrossRef
  • Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 1: risk assessment
    Dong Il Park, Tadakazu Hisamatsu, Minhu Chen, Siew Chien Ng, Choon Jin Ooi, Shu Chen Wei, Rupa Banerjee, Ida Normiha Hilmi, Yoon Tae Jeen, Dong Soo Han, Hyo Jong Kim, Zhihua Ran, Kaichun Wu, Jiaming Qian, Pin-Jin Hu, Katsuyoshi Matsuoka, Akira Andoh, Yasu
    Intestinal Research.2018; 16(1): 4.     CrossRef
  • Asian Organization for Crohn's and Colitis and Asian Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti‐tumor necrosis factor treatment. Part 1: Risk assessment
    Dong II Park, Tadakazu Hisamatsu, Minhu Chen, Siew Chien Ng, Choon Jin Ooi, Shu Chen Wei, Rupa Banerjee, Ida Normiha Hilmi, Yoon Tae Jeen, Dong Soo Han, Hyo Jong Kim, Zhihua Ran, Kaichun Wu, Jiaming Qian, Pin‐Jin Hu, Katsuyoshi Matsuoka, Akira Andoh, Yasu
    Journal of Gastroenterology and Hepatology.2018; 33(1): 20.     CrossRef
  • Differential diagnosis of inflammatory bowel disease: imitations and complications
    Krisztina B Gecse, Severine Vermeire
    The Lancet Gastroenterology & Hepatology.2018; 3(9): 644.     CrossRef
  • Management of Crohn's disease in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease
    Shu-Chen Wei, Ting-An Chang, Te-Hsin Chao, Jinn-Shiun Chen, Jen-Wei Chou, Yenn-Hwei Chou, Chiao-Hsiung Chuang, Wen-Hung Hsu, Tien-Yu Huang, Tzu-Chi Hsu, Chun-Chi Lin, Hung-Hsin Lin, Jen-Kou Lin, Wei-Chen Lin, Yen-Hsuan Ni, Ming-Jium Shieh, I-Lun Shih, Chi
    Intestinal Research.2017; 15(3): 285.     CrossRef
  • Development and Validation of a Novel Prediction Model for Differential Diagnosis Between Crohnʼs Disease and Intestinal Tuberculosis
    Jung Ho Bae, Sang Hyoung Park, Byong Duk Ye, Seon-Ok Kim, Yun Kyung Cho, Eun Ja Youn, Ho-Su Lee, Sung Wook Hwang, Dong-Hoon Yang, Kyung-Jo Kim, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang
    Inflammatory Bowel Diseases.2017; 23(9): 1614.     CrossRef
  • Evaluation of Xpert MTB/RIF assay performance in the diagnosis of abdominal tuberculosis
    Suraj Kumar, Sawan Bopanna, Saurabh Kedia, Pratap Mouli, Rajan Dhingra, Rajesh Padhan, Mikashmi Kohli, Jigyasa Chaubey, Rohini Sharma, Prasenjit Das, S Dattagupta, Govind Makharia, SK Sharma, Vineet Ahuja
    Intestinal Research.2017; 15(2): 187.     CrossRef
  • Temporal trends in the misdiagnosis rates between Crohn’s disease and intestinal tuberculosis
    Hyungil Seo, Seohyun Lee, Hoonsub So, Donghoi Kim, Seon-Ok Kim, Jae Seung Soh, Jung Ho Bae, Sun-Ho Lee, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kyung-Jo Kim, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Byong Duk Ye
    World Journal of Gastroenterology.2017; 23(34): 6306.     CrossRef
  • Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease
    Shu-Chen Wei, Ting-An Chang, Te-Hsin Chao, Jinn-Shiun Chen, Jen-Wei Chou, Yenn-Hwei Chou, Chiao-Hsiung Chuang, Wen-Hung Hsu, Tien-Yu Huang, Tzu-Chi Hsu, Chun-Chi Lin, Hung-Hsin Lin, Jen-Kou Lin, Wei-Chen Lin, Yen-Hsuan Ni, Ming-Jium Shieh, I-Lun Shih, Chi
    Intestinal Research.2017; 15(3): 266.     CrossRef
  • Is it intestinal tuberculosis again? Case report
    Kristián Brat, Zdeněk Merta, Ivan Čundrle
    Vnitřní lékařství.2017; 63(5): 354.     CrossRef
  • Pediatric inflammatory bowel disease
    Akshay Kapoor, Vidyut Bhatia, Anupam Sibal
    Indian Pediatrics.2016; 53(11): 993.     CrossRef
  • Change in the diagnosis of inflammatory bowel disease: a hospital-based cohort study from Korea
    Ho-Su Lee, Jaewon Choe, Hyo Jeong Lee, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kyung-Jo Kim, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Yong Sik Yoon, Chang Sik Yu, Jin-Ho Kim, Suk-Kyun Yang
    Intestinal Research.2016; 14(3): 258.     CrossRef
  • Differences in Clinical Manifestations according to the Positivity of Interferon-γ Assay in Patients with Intestinal Tuberculosis
    Hye Jin Jung, Young-Ho Kim, You Sun Kim, Seong Yeon Jeong, Sung Won Park, Ji Yeon Seo, Hyemi Jung, Jong Pil Im, Ji Won Kim, Sung Noh Hong, Kuk Lae Lee
    Gut and Liver.2016; 10(4): 649.     CrossRef
  • Clinical and Laboratory Diagnosis of Intestinal Tuberculosis
    Xiao-Chun Shi, Li-Fan Zhang, Yue-Qiu Zhang, Xiao-Qing Liu, Gui-Jun Fei
    Chinese Medical Journal.2016; 129(11): 1330.     CrossRef
  • Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a case report
    Madunil A. Niriella, S. Kuleesha Kodisinghe, Arjuna P. De Silva, Janaki Hewavisenthi, Hithanadura J. de Silva
    BMC Research Notes.2016;[Epub]     CrossRef
  • Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis
    Jiang-Peng Wei, Xiao-Yan Wu, Sen-Yang Gao, Qiu-Yu Chen, Tong Liu, Gang Liu
    Medicine.2016; 95(1): e2436.     CrossRef
  • When it is not inflammatory bowel disease
    Edouard Louis
    Current Opinion in Gastroenterology.2015; 31(4): 283.     CrossRef
  • 5,923 View
  • 69 Download
  • 22 Web of Science
  • 24 Crossref
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Reviews
Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases
Sung Hee Lee
Intest Res 2015;13(1):11-18.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.11
AbstractAbstract PDFPubReader

Epithelial tight junctions (TJs) are the key structures regulating paracellular trafficking of macromolecules. The TJ is multi-protein complex that forms a selective permeable seal between adjacent epithelial cells and demarcates the boundary between apical and basolateral membrane domains. Disruption of the intestinal TJ barrier, followed by permeation of luminal noxious molecules, induces a perturbation of the mucosal immune system and inflammation, which can act as a trigger for the development of intestinal and systemic diseases. Inflammatory bowel disease (IBD) patients demonstrate increased intestinal paracellular permeability. Although it remains unclear whether barrier dysfunction precedes disease or results from active inflammation, increased intestinal TJ disruption is observed in IBD patients suggest that dysregulation of TJ barrier integrity may predispose or enhance IBD progression. Therefore, therapeutic target to restore the TJ barrier integrity may provide effective therapeutic and preventive approaches against IBD. This review discusses the molecular structure and regulation of intestinal TJs and the involvement of intestinal TJs in IBD pathogenesis.

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  • Sleep deprivation-induced shifts in gut microbiota: Implications for neurological disorders
    Nitu L. Wankhede, Mayur B. Kale, Ashishkumar Kyada, Rekha M M, Kamlesh Chaudhary, K.Satyam Naidu, Sandip Rahangdale, Prajwali V. Shende, Brijesh G. Taksande, Mohammad Khalid, Monica Gulati, Milind J. Umekar, Mohammad Fareed, Spandana Rajendra Kopalli, Sus
    Neuroscience.2025; 565: 99.     CrossRef
  • Sodium butyrate prevents lipopolysaccharide induced inflammation and restores the expression of tight junction protein in human epithelial Caco-2 cells
    Jyotsana Bakshi, K.P. Mishra
    Cellular Immunology.2025; 408: 104912.     CrossRef
  • Prevention and potential repair of colitis: Beneficial effects and regulatory mechanisms of food-derived anti-inflammatory peptides
    Renzhi Lv, Na Sun, Chuwen Mao, Zhihong Zheng, Songyi Lin
    Critical Reviews in Food Science and Nutrition.2024; 64(23): 8184.     CrossRef
  • Understanding the Effect of Compound Probiotics on the Health of Rabbits and Its Mechanisms Through Metagenomics
    Xiaohong Hou, Peiqiang Dai, Xingdong Song, Xianrong Long, Jing Gao, Tongjie Chai
    Probiotics and Antimicrobial Proteins.2024; 16(3): 815.     CrossRef
  • Mannose attenuates intestinal epithelial tight junction damage in experimental colitis mice by activating the AXIN-AMPK pathway
    Wenxin Liu, Jingwen Xie, Honglian Jiang, Jia Zhou, Xiao Lu, Daming Zuo, Lijun Dong, Qingyun Chen
    International Immunopharmacology.2024; 127: 111319.     CrossRef
  • The role of the gastrointestinal barrier in obesity‐associated systemic inflammation
    Adriana Acciarino, Shanti Diwakarla, Jessica Handreck, Cedrick Bergola, Lauren Sahakian, Rachel M. McQuade
    Obesity Reviews.2024;[Epub]     CrossRef
  • Synthesis and antibacterial activity of FST and its effects on inflammatory response and intestinal barrier function in mice infected with Escherichia coli O78
    Wenbo Ge, Zhun Li, Yajun Yang, Xiwang Liu, Zhaohan Zhu, Lixia Bai, Zhe Qin, Xiao Xu, Jianyong Li, Shihong Li
    International Immunopharmacology.2024; 127: 111386.     CrossRef
  • Lactiplantibacillus plantarum HY7718 Improves Intestinal Integrity in a DSS-Induced Ulcerative Colitis Mouse Model by Suppressing Inflammation through Modulation of the Gut Microbiota
    Hyeon-Ji Kim, Hye-Jin Jeon, Joo-Yun Kim, Jae-Jung Shim, Jae-Hwan Lee
    International Journal of Molecular Sciences.2024; 25(1): 575.     CrossRef
  • Gastro‐Intestinal Digested Bovine Milk Osteopontin Modulates Gut Barrier Biomarkers In Vitro
    Lu Li, Juchun Chen, Yuxing Zheng, Jonathan Lane, Ruibiao Hu, Jianzhong Zhu, Xiong Fu, Qiang Huang, Feitong Liu, Bin Zhang
    Molecular Nutrition & Food Research.2024;[Epub]     CrossRef
  • Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier
    Tong Chen, Naizhong Jin, Qi Zhang, Zhongming Li, Qiutao Wang, Xuedong Fang
    Inflammation.2024; 47(4): 1127.     CrossRef
  • Gut-Brain Axis Impact on Canine Anxiety Disorders: New Challenges for Behavioral Veterinary Medicine
    Carina Sacoor, John D. Marugg, Nuno R. Lima, Nuno Empadinhas, Liliana Montezinho, Alessandro Di Cerbo
    Veterinary Medicine International.2024; 2024: 1.     CrossRef
  • ROS-responsive nanoparticles targeting inflamed colon for synergistic therapy of inflammatory bowel disease via barrier repair and anti-inflammation
    Ding Wang, Qi Jiang, Ruoyu Shen, Lijun Peng, Wentao Zhou, Tingting Meng, Fuqiang Hu, Jianwei Wang, Hong Yuan
    Nano Research.2024; 17(6): 5409.     CrossRef
  • Assessing cytotoxicity and endoplasmic reticulum stress in human blood–brain barrier cells due to silver and copper oxide nanoparticles
    Luiza Chojnacka-Puchta, Dorota Sawicka, Lidia Zapor, Katarzyna Miranowicz-Dzierzawska
    Journal of Applied Genetics.2024;[Epub]     CrossRef
  • Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice
    Yu-Hong Yang, Chen Chen, Yan Zheng, Zi-Jian Wu, Meng-Qing Zhou, Xiao-Yong Liu, Kazuo Miyashita, De-Lin Duan, Lei Du
    Journal of Agricultural and Food Chemistry.2024; 72(8): 4142.     CrossRef
  • Elaidic acid-induced intestinal barrier damage led to gut-liver axis derangement and triggered NLRP3 inflammasome in the liver of SD rats
    Hui Liu, Xuenan Li, Lu Li, Yucai Li, Haiyang Yan, Yong Pang, Wenliang Li, Yuan Yuan
    Food Science and Human Wellness.2024; 13(3): 1279.     CrossRef
  • Taurine Alleviates Experimental Colitis by Enhancing Intestinal Barrier Function and Inhibiting Inflammatory Response through TLR4/NF-κB Signaling
    Jiaming Zheng, Jinglin Zhang, Yewen Zhou, Di Zhang, Hongzhou Guo, Bin Li, Sheng Cui
    Journal of Agricultural and Food Chemistry.2024; 72(21): 12119.     CrossRef
  • Experimental colitis-induced visceral hypersensitivity is attenuated by GABA treatment in mice
    Michael S. Gold, Emanuel Loeza-Alcocer
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2024; 326(3): G252.     CrossRef
  • Sodium butyrate administration improves intestinal development of suckling lambs
    Mengzhen Sun, Wenwen Ji, Hongwei Ye, Yitao Cai, Yan Yun, Xiaoshi Wei, Chong Wang, Huiling Mao
    Journal of Animal Science.2024;[Epub]     CrossRef
  • Stress-induced changes in cognitive function and intestinal barrier integrity can be ameliorated by venlafaxine and synbiotic supplementations
    Sarawut Lapmanee, Nattapon Supkamonseni, Sakkarin Bhubhanil, Nattakan Treesaksrisakul, Chaiyos Sirithanakorn, Mattaka Khongkow, Katawut Namdee, Piyaporn Surinlert, Chittipong Tipbunjong, Prapimpun Wongchitrat
    PeerJ.2024; 12: e17033.     CrossRef
  • 5S-Heudelotinone alleviates experimental colitis by shaping the immune system and enhancing the intestinal barrier in a gut microbiota-dependent manner
    Qing Meng, Jianshuang Guo, Ke Lv, Yang Liu, Jin Zhang, Mingyue Li, Xirui Cheng, Shenghua Chen, Xiaoguang Huo, Quan Zhang, Yue Chen, Jing Li
    Acta Pharmaceutica Sinica B.2024;[Epub]     CrossRef
  • Lycopene Ameliorated DSS-Induced Colitis by Improving Epithelial Barrier Functions and Inhibiting the Escherichia coli Adhesion in Mice
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    Journal of Agricultural and Food Chemistry.2024; 72(11): 5784.     CrossRef
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    Shuaichen Liu, Lan Hong, Song Zhang, Yuxin Tian, Yuchen Wang, Duanduan Zhao, Jingheng Lv, Jingjing Zhuang, Hongyan Xu, Guangjun Xia
    International Journal of Biological Macromolecules.2024; 265: 130863.     CrossRef
  • The individual response to antibiotics and diet — insights into gut microbial resilience and host metabolism
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    Nature Reviews Endocrinology.2024; 20(7): 387.     CrossRef
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    Foods.2024; 13(6): 898.     CrossRef
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    International Journal of Pharmacology.2024; 20(3): 361.     CrossRef
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    Journal of Hazardous Materials.2024; 470: 134209.     CrossRef
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    Han Su Lee, Jong Min Kim, Hyo Lim Lee, Min Ji Go, Dong Yeol Lee, Chul-Woo Kim, Hyun-Jin Kim, Ho Jin Heo
    International Journal of Molecular Sciences.2024; 25(7): 4063.     CrossRef
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  • The ethanolic extract of domesticated Amauroderma rugosum alleviated DSS-induced ulcerative colitis via repairing the intestinal barrier
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    Food Science and Biotechnology.2024; 33(14): 3335.     CrossRef
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    Biomaterials Science.2024; 12(12): 3212.     CrossRef
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    International Journal of Molecular Sciences.2024; 25(11): 5817.     CrossRef
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    Stefan Panaiotov, Lyubka Tancheva, Reni Kalfin, Polina Petkova-Kirova
    Molecules.2024; 29(11): 2614.     CrossRef
  • Beneficial effects of Dendrobium officinale National Herbal Drink on metabolic immune crosstalk via regulate SCFAs-Th17/Treg
    Ying-Jie Dong, Yi-Piao Zhang, Xiao-Feng Jiang, Zhi-Yi Xie, Bo Li, Ning-Hua Jiang, Su-Hong Chen, Gui-Yuan Lv
    Phytomedicine.2024; 132: 155816.     CrossRef
  • The Role of Nanoparticle Morphology on Enhancing Delivery of Budesonide for Treatment of Inflammatory Bowel Disease
    Qiuyu Li, Wenjuan Liu, Kaiheng Liu, Zirong Dong, Weiwen Kong, Xinrui Lu, Yuning Wei, Wei Wu, Jinlong Yang, Jianping Qi
    ACS Applied Materials & Interfaces.2024; 16(26): 33081.     CrossRef
  • AG1®, a Novel Synbiotic, Maintains Gut Barrier Function following Inflammatory Challenge in a Caco-2/THP1-Blue™ Co-Culture Model
    Philip A. Sapp, Jeremy R. Townsend, Trevor O. Kirby, Marlies Govaert, Cindy Duysburgh, Lynn Verstrepen, Massimo Marzorati, Tess M. Marshall, Ralph Esposito
    Microorganisms.2024; 12(7): 1263.     CrossRef
  • Tauroursodeoxycholic Acid Reverses Dextran Sulfate Sodium-Induced Colitis in Mice via Modulation of Intestinal Barrier Dysfunction and Microbiome Dysregulation
    Longbiao Luo, Yi Zhao, Guangji Zhang, Sijing Dong, YinYue Xu, Hehe Shi, Menggai Zhang, Xue Liu, Sicen Wang, Hua Luo, Wanghui Jing
    Journal of Pharmacology and Experimental Therapeutics.2024; 390(1): 116.     CrossRef
  • Bacillus coagulans restores pathogen-induced intestinal dysfunction via acetate–FFAR2–NF-κB–MLCK–MLC axis in Apostichopus japonicus
    Mingshan Song, Shanshan Zhang, Zhen Zhang, Liyuan Guo, Weikang Liang, Chenghua Li, Zhonghua Wang, Jean-Baptiste Raina
    mSystems.2024;[Epub]     CrossRef
  • Phytoconstituent-derived nano-medicines/vesicles providing a promising dawn for inflammatory bowel disease
    Linzhou Yin, Xiaowen Jiang, Miao Wang, Yiren Yang, Zhonggui He, Jin Sun, Huiyuan Gao, Mengchi Sun
    Chinese Chemical Letters.2024; : 110224.     CrossRef
  • Lactobacillus reuteri alleviates LPS-induced intestinal mucosal damage by stimulating the expansion of intestinal stem cells via activation of the Wnt/β-catenin signaling pathway in broilers
    Xiaoqing Ding, Runzi Tang, Jiayue Zhao, Yibin Xu, Aikun Fu, Xiuan Zhan
    Poultry Science.2024; 103(10): 104072.     CrossRef
  • Lacticaseibacillus casei IB1 Alleviates DSS-Induced Inflammatory Bowel Disease by Regulating the Microbiota and Restoring the Intestinal Epithelial Barrier
    Jianlong Lao, Shuping Yan, Yanhong Yong, Yin Li, Zhaohai Wen, Xiaoyong Zhang, Xianghong Ju, Youquan Li
    Microorganisms.2024; 12(7): 1379.     CrossRef
  • Carp growth, body composition, lipidomics, and flesh quality in response to replacing dietary fish meal with a complex protein source
    Aoran Zhang, Hongmei Wang, Yunfan Zheng, Wang Yin, Xiheng Cai, Yong Li, Yunxiang Liang
    Aquaculture Reports.2024; 37: 102232.     CrossRef
  • Uncovering the mechanism of Clostridium butyricum CBX 2021 to improve pig health based on in vivo and in vitro studies
    Xin Liu, Xiaoyu Qiu, Yong Yang, Jing Wang, Qi Wang, Jingbo Liu, Jinxiu Huang, Feiyun Yang, Zuohua Liu, Renli Qi
    Frontiers in Microbiology.2024;[Epub]     CrossRef
  • Intersecting Pathways: The Role of Metabolic Dysregulation, Gastrointestinal Microbiome, and Inflammation in Acute Ischemic Stroke Pathogenesis and Outcomes
    Jarosław Nuszkiewicz, Beata Kukulska-Pawluczuk, Katarzyna Piec, Dorian Julian Jarek, Karina Motolko, Karolina Szewczyk-Golec, Alina Woźniak
    Journal of Clinical Medicine.2024; 13(14): 4258.     CrossRef
  • Exposure to microcystin-LR promotes the progression of colitis-associated colorectal cancer by inducing barrier disruption and gut microbiota dysbiosis
    Yuechi Song, Xiaochang Wang, Xiaohui Lu, Ting Wang
    Ecotoxicology and Environmental Safety.2024; 282: 116750.     CrossRef
  • Squamous papilloma involving the mandible: A case report and descriptive literature review
    Xin Zheng, Lianlian Liu, Congyuan Cao, Shuojin Huang, Dongxiao Tang, Shuai Li, Qianting He
    Experimental and Therapeutic Medicine.2024;[Epub]     CrossRef
  • Targeting gut microbiota and metabolism profiles with coated sodium butyrate to ameliorate high-energy and low-protein diet-induced intestinal barrier dysfunction in laying hens
    Sasa Miao, Jiankui Li, Ying Chen, Wenyan Zhao, Mengru Xu, Fang Liu, Xiaoting Zou, Xinyang Dong
    Animal Nutrition.2024; 19: 104.     CrossRef
  • Vitamin D/vitamin D receptor protects intestinal barrier against colitis by positively regulating Notch pathway
    Yanni Li, Yaoyu Guo, Chong Geng, Shuailing Song, Wenjuan Yang, Xiao Li, Chunhui Wang
    Frontiers in Pharmacology.2024;[Epub]     CrossRef
  • Peroxisomal cholesterol metabolism regulates yap-signaling, which maintains intestinal epithelial barrier function and is altered in Crohn’s disease
    Marinella Pinelli, Stephanie Makdissi, Michal Scur, Brendon D. Parsons, Kristi Baker, Anthony Otley, Brad MacIntyre, Huong D. Nguyen, Peter K. Kim, Andrew W. Stadnyk, Francesca Di Cara
    Cell Death & Disease.2024;[Epub]     CrossRef
  • Enhancing intestinal health with germinated oats: Bioinformatics and compound profiling insights into a novel approach for managing inflammatory bowel disease
    Hyeon Jae Lee, Kyeong Jin Kim, Soo-yeon Park, Kwanyong Choi, Jaeho Pyee, Sunyong Yoo, Ji Yeon Kim
    Food Bioscience.2024; 61: 104833.     CrossRef
  • Enteroendocrine Cells Regulate Intestinal Homeostasis and Epithelial Function
    Jennifer G. Nwako, Heather A. McCauley
    Molecular and Cellular Endocrinology.2024; : 112339.     CrossRef
  • Diacylglycerol O-acyltransferase 1 inhibitor increases plasma alanine aminotransferase and aspartate aminotransferase activities via a shedding of the intestinal villi and an increase in intestinal permeability in rats
    Hideaki Yokoyama, Taku Masuyama, Yuki Tanaka, Taishi Shimazaki, Yuzo Yasui, Takuya Abe, Kouichi Yoshinari
    Toxicology Letters.2024; 400: 16.     CrossRef
  • Revitalizing gut barrier integrity: role of miR-192-5p in enhancing autophagy via Rictor in enteritis
    Peishan Qiu, Kezhi Zhou, Youwei Wang, Xiaoyu Chen, Cong Xiao, Wenjie Li, Yuhua Chen, Ying Chang, Jing Liu, Feng Zhou, Xiaobing Wang, Jian Shang, Lan Liu, Zhao Qiu
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2024; 327(3): G317.     CrossRef
  • Super‐Resolution Imaging in Collagen‐Abundant Thick Tissues
    Ya‐Han Chuang, Yueh‐Feng Wu, Ya‐Hui Lin, Yin‐Hsu Chen, Yu‐Xian Zhou, Shao‐Chun Hsu, Hsin‐Mei Lee, Ann‐Shyn Chiang, Yunching Chen, Shiang‐Jiuun Chen, Sung‐Jan Lin, Li‐An Chu
    Small Structures.2024;[Epub]     CrossRef
  • Mechanism of Action and Therapeutic Implications of Nrf2/HO-1 in Inflammatory Bowel Disease
    Lingling Yuan, Yingyi Wang, Na Li, Xuli Yang, Xuhui Sun, Huai’e Tian, Yi Zhang
    Antioxidants.2024; 13(8): 1012.     CrossRef
  • Proanthocyanidins and β-Glucan Synergistically Regulate Intestinal Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice
    Pengkui Xia, Ruyi Li, Mianhong Chen, Fanke Zeng, Wei Zhou, Tao Hou
    Journal of Agricultural and Food Chemistry.2024; 72(35): 19366.     CrossRef
  • Crude Blueberry Phenolic Extracts Improve Gut Barrier Integrity and Exert Anti-Inflammatory and Antimicrobial Activity in an In Vitro Weaning Stress Model
    Vignesh B. Nathan, Sarah Eckrote, Shiyu Li, Lavanya Reddivari
    Antioxidants.2024; 13(9): 1044.     CrossRef
  • Utilizing pigs as a model for studying intestinal barrier function
    Marek Pieszka, Kinga Szczepanik, Igor Łoniewski
    Annals of Animal Science.2024;[Epub]     CrossRef
  • PROTAC based STING degrader attenuates acute colitis by inhibiting macrophage M1 polarization and intestinal epithelial cells pyroptosis mediated by STING-NLRP3 axis
    Shuai Xu, Yifeng Peng, Kai Yang, Sheng Liu, Zhanke He, Junli Huang, Ruipei Xiao, Jin Liu, Ziyan Yan, Zhiying Lian, Huayang Pan, Jianjun Chen, Jiaolong Shi, Xingxing Yao, Haijun Deng
    International Immunopharmacology.2024; 141: 112990.     CrossRef
  • On probiotic integration in the management of inflammation and the maintenance of the intestinal epithelial barrier’s integrity
    Giovanna Traina
    Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale.2024;[Epub]     CrossRef
  • Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance
    Qiuping Xiao, Jiaqi Huang, Xiyan Zhu, Min Shi, Liling Chen, Lai Chen, Xuan Liu, Ronghua Liu, Youbao Zhong
    International Immunopharmacology.2024; 142: 113174.     CrossRef
  • Dietary Fermented Blueberry Pomace Supplementation Improves Small Intestinal Barrier Function and Modulates Cecal Microbiota in Aged Laying Hens
    Binghua Qin, Zhihua Li, Qian Zhu, Ting Chen, Wei Lan, Yadong Cui, Md. Abul Kalam Azad, Xiangfeng Kong
    Animals.2024; 14(19): 2786.     CrossRef
  • Human Amniotic Epithelial Stem Cells Promote Colonic Recovery in Experimental Colitis via Exosomal MiR‐23a–TNFR1–NF‐κB Signaling
    Yaohui Kou, Jinying Li, Yingyi Zhu, Jia Liu, Ruizhe Ren, Yuanqing Jiang, Yunyun Wang, Chen Qiu, Jiayi Zhou, Zhuoheng Yang, Tuoying Jiang, Jianan Huang, Xiangyi Ren, Shiguang Li, Cong Qiu, Xiyang Wei, Luyang Yu
    Advanced Science.2024;[Epub]     CrossRef
  • Comparative analysis of bisphenol A effects on HT-29 cell line and mouse intestinal organoids
    Eunju Jang, Changhwan Ahn
    Journal of Biomedical Translational Research.2024; 25(3): 107.     CrossRef
  • Overcoming Biopotency Barriers: Advanced Oral Delivery Strategies for Enhancing the Efficacy of Bioactive Food Ingredients
    Ling Liu, David Julian McClements, Xuebo Liu, Fuguo Liu
    Advanced Science.2024;[Epub]     CrossRef
  • The Effect of CKD-495, Eupacidin, and Their Marker Compounds on Altered Permeability in a Postoperative Ileus Animal Model
    Min-Jae Kim, Zahid Hussain, Young Ju Lee, Hyojin Park
    Medicina.2024; 60(10): 1707.     CrossRef
  • Lactobacillus plantarum 69-2 combined with α-lactalbumin hydrolysate alleviates DSS-induced ulcerative colitis through the TLR4/NF-κB inflammatory pathway and the gut microbiota in mice
    Yue Ma, Chuanbing Hu, Jing Zhang, Cong Xu, Lizhi Ma, Yunhe Chang, Muhammad Altaf Hussain, Jiage Ma, Juncai Hou, Zhanmei Jiang
    Food & Function.2024; 15(22): 10987.     CrossRef
  • Farnesol ameliorates DSS-induced IBD by regulating inflammatory cytokines, repairing the intestinal barrier, reversing the gut microbiota imbalance, and influencing fecal metabolome in C57BL/6 mice
    Ya Yuan, Dazuo Wu, Heping Chen, Zheng Ma, Xinyue Peng, Xiaodie Li, Chuchu Zhao, Linping Jiang, Jinping Liang, Weiwei Zhang, Juan Dai
    Biomedicine & Pharmacotherapy.2024; 180: 117518.     CrossRef
  • Effects of traditional Chinese medicine polysaccharides on chronic diseases by modulating gut microbiota: A review
    Xinyu Li, Riran Zhu, Qian Liu, Henglai Sun, Huagang Sheng, Liqiao Zhu
    International Journal of Biological Macromolecules.2024; 282: 136691.     CrossRef
  • Dietary ω-3 Fatty Acids Mitigate Intestinal Barrier Integrity Alterations in Mice Fed a High-Fat Diet: Implications for Pancreatic Carcinogenesis
    Jazmin Machuca, Joanna Wirkus, Aya S Ead, Payam Vahmani, Karen E Matsukuma, Gerardo G Mackenzie, Patricia I Oteiza
    The Journal of Nutrition.2024;[Epub]     CrossRef
  • Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease
    Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig
    Advanced Healthcare Materials.2024;[Epub]     CrossRef
  • Natural plant polyphenols contribute to the ecological and healthy swine production
    Huadi Mei, Yuanfei Li, Shusong Wu, Jianhua He
    Journal of Animal Science and Biotechnology.2024;[Epub]     CrossRef
  • Tight junction protein changes in irritable bowel syndrome: the relation of age and disease severity
    Sang Un Kim, Ji A Choi, Man-Hoon Han, Jin Young Choi, Ji Hye Park, Moon Sik Kim, Yong Hwan Kwon
    The Korean Journal of Internal Medicine.2024; 39(6): 906.     CrossRef
  • Bifidobacterium bifidum CCFM1163 Alleviates Cathartic Colon Through the Acetate/Propionate‐GPR41‐Gβγ Pathway
    Yin Huang, Nan Tang, Yifan Xue, Jiazhen Li, WenXu Liu, Shengnan Zhu, Linlin Wang, Gang Wang, Wei Chen, Jianxin Zhao
    Food Frontiers.2024;[Epub]     CrossRef
  • Biocompatible carbon dots nanozymes as ROS/RNS modulators for ulcerative colitis alleviation by comprehensively orchestrating intestinal homeostasis
    Wenjing Wang, Guangrong Lu, Zhichao Deng, Huanyu Li, Wenfang He, Shouxing Yang, Yuanyuan Zhu, Chenxi Xu, Yujie Zhang, Lanqi Wang, Xiaoling Huang, Mingzhen Zhang, Changlong Xu
    Chemical Engineering Journal.2024; 502: 157800.     CrossRef
  • Prevalence of bronchiectasis in inflammatory bowel disease: a systematic review and meta-analysis
    Yu Ma, Zhihui Qiang, Miaomiao Zhou, Tianyi Zhang, Zhuoyang Li, Haicheng Zhong, Yue Chang, Zimeng Ning, Yun Liu
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Cellular Plasticity in Gut and Liver Regeneration
    Minwook Kim, Yoojeong Park, You Sun Kim, Sungjin Ko
    Gut and Liver.2024; 18(6): 949.     CrossRef
  • The Leaky Gut and Human Diseases: “Can’t Fill the Cup if You Don’t Plug the Holes First”
    Debora Compare, Costantino Sgamato, Alba Rocco, Pietro Coccoli, Carmen Ambrosio, Gerardo Nardone
    Digestive Diseases.2024; 42(6): 548.     CrossRef
  • Bacteroides fragilis capsular polysaccharide A ameliorates ulcerative colitis in rat by recovering intestinal barrier integrity and restoring gut microbiota
    Yijia Zhong, Xiujuan Chang, Zihan Zhao, Lijun Zheng, Gaobo Kuang, Ping Li, Chenxuexuan Liu, Yuqin Fan, Zhixuan Liang, Ke Zhuang, Qiuling Xie, Yangyang Liu
    Frontiers in Pharmacology.2024;[Epub]     CrossRef
  • Leaky gut in systemic inflammation: exploring the link between gastrointestinal disorders and age-related diseases
    Jonathan Escalante, Olivia Artaiz, Shanti Diwakarla, Rachel M. McQuade
    GeroScience.2024;[Epub]     CrossRef
  • Downregulated KLF4, induced by m6A modification, aggravates intestinal barrier dysfunction in inflammatory bowel disease
    Xingchao Zhu, Jiayu Wang, Huan Zhang, Hongqin Yue, Jinghan Zhu, Juntao Li, Kun Wang, Kanger Shen, Kexi Yang, Xia Leng, Qinhua Xi, Tongguo Shi
    Cellular and Molecular Life Sciences.2024;[Epub]     CrossRef
  • Effects of Dietary Supplementation with Lactobacillus acidophilus and Bacillus subtilis on Mucosal Immunity and Intestinal Barrier Are Associated with Its Modulation of Gut Metabolites and Microbiota in Late-Phase Laying Hens
    Xin Chen, Weiwen Chen, Wenjia Ci, Yingying Zheng, Xinyan Han, Jianping Huang, Jianjin Zhu
    Probiotics and Antimicrobial Proteins.2023; 15(4): 912.     CrossRef
  • Effects of Bacillus methylotrophicus SY200 Supplementation on Growth Performance, Antioxidant Status, Intestinal Morphology, and Immune Function in Broiler Chickens
    Dan Xiao, Zhenhua Wang, Xixi Dai, Yuanwei Hu, Maiyi Zhong, Lvchen Xiong, Chuanheng Jiang, Abdul Khalique, Xueqin Ni, Dong Zeng, Dongmei Zhang, Yan Zeng, Kangcheng Pan
    Probiotics and Antimicrobial Proteins.2023; 15(4): 925.     CrossRef
  • Diets Supplemented with Probiotics Improve the Performance of Broilers Exposed to Heat Stress from 15 Days of Age
    Jéssica C. das D. Ribeiro, Mariana M. Drumond, Pamela Mancha-Agresti, João P. F. Guimarães, Daiane da C. Ferreira, Maria I. A. Martins, Pedro M. de M. Murata, Andressa C. de Carvalho, Raquel T. Pereira, Valdir Ribeiro Júnior, Vasco A. de C. Azevedo, Lucia
    Probiotics and Antimicrobial Proteins.2023; 15(5): 1327.     CrossRef
  • Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome
    Arshia Shahini, Ali Shahini
    Journal of Cell Communication and Signaling.2023; 17(1): 55.     CrossRef
  • Dietary coated essential oil and organic acid mixture supplementation improves health of broilers infected with avian pathogenic Escherichia coli
    Van Hieu Pham, Waseem Abbas, Jinyu Huang, Fangshen Guo, Kaichen Zhang, Linhua Kong, Wenrui Zhen, Yuming Guo, Zhong Wang
    Animal Nutrition.2023; 12: 245.     CrossRef
  • Paeoniflorin‐6′‐O‐benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β‐arrestin 2 on ERK1/2‐NF‐κB
    Mengya Jiang, Caihong Tang, Mei Yang, Ying Li, Wu Wang, Chun Wang, Wei Wei, Jingyu Chen
    Phytotherapy Research.2023; 37(2): 743.     CrossRef
  • Alleviative mechanism and effect of Bifidobacterium animalisA6 on dextran sodium sulfate‐induced ulcerative colitis in mice
    Fang Wu, Guna Wuri, Bing Fang, Mengxuan Shi, Ming Zhang, Liang Zhao
    Food Science & Nutrition.2023; 11(2): 892.     CrossRef
  • Anti-inflammatory mechanisms of polyphenols in adipose tissue: role of gut microbiota, intestinal barrier integrity and zinc homeostasis
    Tariful Islam, Kembra Albracht-Schulte, Latha Ramalingam, Natalia Schlabritz-Lutsevich, Oak-Hee Park, Masoud Zabet-Moghaddam, Nishan S. Kalupahana, Naima Moustaid-Moussa
    The Journal of Nutritional Biochemistry.2023; 115: 109242.     CrossRef
  • Effects of β-alanine on intestinal development and immune performance of weaned piglets
    Linlin Chen, Yan Zhong, Xiangqin Ouyang, Chunfeng Wang, Lanmei Yin, Jing Huang, Yali Li, Qiye Wang, Junyan Xie, Pengfei Huang, Huansheng Yang, Yulong Yin
    Animal Nutrition.2023; 12: 398.     CrossRef
  • Ferric citrate-induced colonic mucosal damage associated with oxidative stress, inflammation responses, apoptosis, and the changes of gut microbial composition
    Yu Xia, Qihui Luo, Chao Huang, Liangqin Shi, Asad Jahangir, Ting Pan, Xiaoli Wei, Junbo He, Wentao Liu, Riyi Shi, Yi Geng, Jing Fang, Li Tang, Hongrui Guo, Ping Ouyang, Zhengli Chen
    Ecotoxicology and Environmental Safety.2023; 249: 114364.     CrossRef
  • Protective effect of 7-hydroxyl-1-methylindole-3-acetonitrile on the intestinal mucosal damage response to inflammation in mice with DSS-induced colitis
    Kyung-Sook Chung, Sang-Eun Park, Jung-Hun Lee, Su-Yeon Kim, Hee-Soo Han, Yong Sup Lee, Seang-Hwan Jung, Eungyeong Jang, Sangmin Lee, Kyung-Tae Lee
    Chemico-Biological Interactions.2023; 370: 110316.     CrossRef
  • Intestinal mucosal and fecal microbiota profiles in Crohn's disease in Chinese children
    Peilin Wu, Bin Wu, Zehao Zhuang, Junhong Liu, Linliang Hong, Bihong Ma, Biyun Lin, Junxi Wang, Chenye Lin, Junhong Chen, Suqing Chen
    Medicine in Microecology.2023; 15: 100071.     CrossRef
  • Pingyin Rose Essential Oil Restores Intestinal Barrier Integrity in DSS-induced Mice Colitis Model
    Rifat Nowshin Raka, Junsong Xiao, Hua Wu, Wenwen Lv, Zhiqian Ding, Yangping Cao, Xukai Li, Jinglong Sun, Kou Luan
    Food Research International.2023; 164: 112362.     CrossRef
  • Protective effect of Paecilomyces cicadae TJJ11213 exopolysaccharide on intestinal mucosa and regulation of gut microbiota in immunosuppressed mice
    Juanjuan Tian, Xiaogan Zhao, Chao Tang, Xiaomeng Wang, Xueliang Zhang, Luyao Xiao, Wei Li
    Food Research International.2023; 165: 112477.     CrossRef
  • Dietary and phytogenic inclusion effects on the broiler chicken cecal ecosystem
    Irida Palamidi, Vasileios V. Paraskeuas, Konstantinos C. Mountzouris
    Frontiers in Animal Science.2023;[Epub]     CrossRef
  • Huangshui Polysaccharide Exerts Intestinal Barrier Protective Effects through the TLR4/MyD88/NF-κB and MAPK Signaling Pathways in Caco-2 Cells
    Jiaying Huo, Wenhao Pei, Guoying Liu, Weizheng Sun, Jihong Wu, Mingquan Huang, Wei Lu, Jinyuan Sun, Baoguo Sun
    Foods.2023; 12(3): 450.     CrossRef
  • IBD disease-modifying therapies: insights from emerging therapeutics
    Niranjan G. Kotla, Yury Rochev
    Trends in Molecular Medicine.2023; 29(3): 241.     CrossRef
  • Beyond allergic progression: From molecules to microbes as barrier modulators in the gut-lung axis functionality
    Jorge Parrón-Ballesteros, Rubén García Gordo, Juan Carlos López-Rodríguez, Nieves Olmo, Mayte Villalba, Eva Batanero, Javier Turnay
    Frontiers in Allergy.2023;[Epub]     CrossRef
  • Acute high-fat diet impairs macrophage-supported intestinal damage resolution
    Andrea A. Hill, Myunghoo Kim, Daniel F. Zegarra-Ruiz, Lin-Chun Chang, Kendra Norwood, Adrien Assié, Wan-Jung H. Wu, Michael C. Renfroe, Hyo Wong Song, Angela M. Major, Buck S. Samuel, Joseph M. Hyser, Randy S. Longman, Gretchen E. Diehl
    JCI Insight.2023;[Epub]     CrossRef
  • Treatment Effects of Natural Products on Inflammatory Bowel Disease In Vivo and Their Mechanisms: Based on Animal Experiments
    Yaxi Zhou, Diandian Wang, Wenjie Yan
    Nutrients.2023; 15(4): 1031.     CrossRef
  • Immunity‐on‐a‐Chip: Integration of Immune Components into the Scheme of Organ‐on‐a‐Chip Systems
    Qasem Ramadan, Rana Hazaymeh, Mohammed Zourob
    Advanced Biology.2023;[Epub]     CrossRef
  • Therapeutic and prophylactic role of vitamin D and curcumin in acetic acid-induced acute ulcerative colitis model
    Ayse Seda Erarslan, Recep Ozmerdivenli, Ferhat Sirinyıldız, Ozge Cevik, Erkan Gumus, Gokhan Cesur
    Toxicology Mechanisms and Methods.2023; 33(6): 480.     CrossRef
  • Prospective Use of Probiotics to Maintain Astronaut Health during Spaceflight
    Sahaj Bharindwal, Nidhi Goswami, Pamela Jha, Siddharth Pandey, Renitta Jobby
    Life.2023; 13(3): 727.     CrossRef
  • Gut microbiome and renal transplantation
    Patrícia Kleinová, Monika Beliančinová, Matej Vnučák, Karol Graňák, Ivana Dedinská
    Vnitřní lékařství.2023; 69(1): 41.     CrossRef
  • Coxsackie B – Pantropic Viruses
    Beata Gad, Magdalena Wieczorek
    Postępy Mikrobiologii - Advancements of Microbiology.2023; 62(1): 13.     CrossRef
  • Cis-Nerolidol Inhibits MAP Kinase and NF-κB Signaling Pathways and Prevents Epithelial Tight Junction Dysfunction in Colon Inflammation: In Vivo and In Vitro Studies
    Vishnu Raj, Balaji Venkataraman, Shreesh K. Ojha, Saeeda Almarzooqi, Veedamali S. Subramanian, Basel K. Al-Ramadi, Thomas E. Adrian, Sandeep B. Subramanya
    Molecules.2023; 28(7): 2982.     CrossRef
  • Anti-Inflammatory, Barrier Maintenance, and Gut Microbiome Modulation Effects of Saccharomyces cerevisiae QHNLD8L1 on DSS-Induced Ulcerative Colitis in Mice
    Qianjue Hu, Leilei Yu, Qixiao Zhai, Jianxin Zhao, Fengwei Tian
    International Journal of Molecular Sciences.2023; 24(7): 6721.     CrossRef
  • Stachyose modulates gut microbiota and alleviates DSS-induced ulcerative colitis in mice
    Chen Wang, Junying Bai, Botao Wang, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Huayi Suo, Wei Chen, Qixiao Zhai
    Food Science and Human Wellness.2023; 12(6): 2211.     CrossRef
  • Fate and distribution of orally-ingested CeO2-nanoparticles based on a mouse model: Implication for human health
    Xingmao Ma, Xiaoxuan Wang, Lei Xu, Honglan Shi, Hu Yang, Kerstin K. Landrock, Virender K. Sharma, Robert S. Chapkin
    Soil & Environmental Health.2023; 1(2): 100017.     CrossRef
  • Lactobacillus paracaseiinfluences the gut-microbiota-targeted metabolic modulation of the immune status of diarrheal mice
    Shunan Ren, Chunjie Wang, Aorigele Chen, Zhaoxing Bai, Yanping Tian, Wenting Lv
    Food & Function.2023; 14(9): 4368.     CrossRef
  • Dietary 5-demethylnobiletin prevents antibiotic-associated dysbiosis of gut microbiota and damage to the colonic barrier
    Minmin Zhan, Xinyan Liang, Jiaqi Chen, Xiaoshuang Yang, Yanhui Han, Chenxi Zhao, Jie Xiao, Yong Cao, Hang Xiao, Mingyue Song
    Food & Function.2023; 14(9): 4414.     CrossRef
  • Maternal sodium acetate supplementation promotes lactation performance of sows and their offspring growth performance
    Yingao Qi, Tenghui Zheng, Siwang Yang, Qianzi Zhang, Baofeng Li, Xiangfang Zeng, Yongxing Zhong, Fang Chen, Wutai Guan, Shihai Zhang
    Animal Nutrition.2023; 14: 213.     CrossRef
  • Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway
    Yuan-Feng Zou, Cen-Yu Li, Yu-Ping Fu, Xiao-Ping JiZe, Yu-Zhe Zhao, Xi Peng, Jing-Yi Wang, Zhong-Qiong Yin, Yang-Ping Li, Xu Song, Li-Xia Li, Xing-Hong Zhao, Bin Feng, Chao Huang, Gang Ye, Hua-Qiao Tang, Ji Chen, Rui Li, Xing-Fu Chen, Meng-Liang Tian
    International Journal of Biological Macromolecules.2023; 242: 124689.     CrossRef
  • Integrin β6 deficiency protects mice from experimental colitis and colitis-associated carcinoma by altering macrophage polarization
    Qi Sun, Zhihua Lu, Lei Ma, Dong Xue, Chang Liu, Changchun Ye, Wenbo Huang, Yueyan Dang, Fanni Li
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • Fermented Sargassum fusiforme Mitigates Ulcerative Colitis in Mice by Regulating the Intestinal Barrier, Oxidative Stress, and the NF-κB Pathway
    Siteng Zhang, Yu Cao, Zixuan Wang, Huanhuan Liu, Yue Teng, Guopeng Li, Jiaxiu Liu, Xiaodong Xia
    Foods.2023; 12(10): 1928.     CrossRef
  • Pingwei San Ameliorates Spleen Deficiency-Induced Diarrhea through Intestinal Barrier Protection and Gut Microbiota Modulation
    Yimeng Fan, Qingyu Zhao, Yuanyuan Wei, Huiru Wang, Yu Ga, Yannan Zhang, Zhihui Hao
    Antioxidants.2023; 12(5): 1122.     CrossRef
  • Digested Cinnamon (Cinnamomum verum J. Presl) Bark Extract Modulates Claudin-2 Gene Expression and Protein Levels under TNFα/IL-1β Inflammatory Stimulus
    Elena Lonati, Gessica Sala, Paolo Corbetta, Stefania Pagliari, Emanuela Cazzaniga, Laura Botto, Pierangela Rovellini, Ilaria Bruni, Paola Palestini, Alessandra Bulbarelli
    International Journal of Molecular Sciences.2023; 24(11): 9201.     CrossRef
  • Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays
    Susan S. Schiffman, Elizabeth H. Scholl, Terrence S. Furey, H. Troy Nagle
    Journal of Toxicology and Environmental Health, Part B.2023; 26(6): 307.     CrossRef
  • Bacillus coagulans GBI-30, 6086 (BC30) improves lactose digestion in rats exposed to a high-lactose meal
    Joan Teichenné, Úrsula Catalán, Roger Mariné-Casadó, Cristina Domenech-Coca, Anna Mas-Capdevila, Juan María Alcaide-Hidalgo, Gertruda Chomiciute, Ana Rodríguez-García, Ana Hernández, Vanessa Gutierrez, Francesc Puiggròs, Josep M. Del Bas, Antoni Caimari
    European Journal of Nutrition.2023; 62(6): 2649.     CrossRef
  • Antiviral properties of breast milk: a new area of research
    S. G. Gribakin, S. V. Orlova, I. V. Podoprigora
    Medical alphabet.2023; (8): 64.     CrossRef
  • Dietary lysozyme improves growth performance and intestinal barrier function of weaned piglets
    Yuying Wu, Bei Cheng, Longxiang Ji, Xiangyun Lv, Yingying Feng, Liu’an Li, Xin Wu
    Animal Nutrition.2023; 14: 249.     CrossRef
  • Herbicide propisochlor exposure induces intestinal barrier impairment, microbiota dysbiosis and gut pyroptosis
    Yunle Liu, Lin Ye, Huodai Chen, Karl Wah Keung Tsim, Xing Shen, Xiangmei Li, Xueling Li, Hongtao Lei
    Ecotoxicology and Environmental Safety.2023; 262: 115154.     CrossRef
  • The Early Impact of Diets Enriched with Saturated and Unsaturated Fatty Acids on Intestinal Inflammation and Tight Junctions.
    Patrícia Brito Rodrigues, Marcella Neves Dátilo, Marcella Ramos Sant'Ana, Guilherme Augusto da Silva Nogueira, Rodrigo Miguel Marin, Susana Castelo Branco Ramos Nakandakari, Leandro Pereira de Moura, Adelino Sanchez Ramos da Silva, Eduardo Rochete Ropelle
    The Journal of Nutritional Biochemistry.2023; : 109410.     CrossRef
  • Efficacy of pectins with different degrees of methyl-esterification and of blockiness in preventing gut epithelial cell barrier disruption and the impact on sodium–glucose co-transporter expression under low and high glucose conditions
    Xin Tang, Martin Beukema, Michela Ferrari, Marthe T. C. Walvoort, Bart J. de Haan, Paul de Vos
    Food & Function.2023; 14(13): 6226.     CrossRef
  • Aloe-derived nanovesicles attenuate inflammation and enhance tight junction proteins for acute colitis treatment
    Sang-Hun Choi, Jung-Young Eom, Hyun-Jin Kim, Wonhyo Seo, Hyo-Jung Kwun, Do-Kyun Kim, Jihoon Kim, Young-Eun Cho
    Biomaterials Science.2023; 11(16): 5490.     CrossRef
  • Chronotoxicity of Acrylamide in Mice Fed a High-Fat Diet: The Involvement of Liver CYP2E1 Upregulation and Gut Leakage
    Luanfeng Wang, Yanhong Liu, Huajing Gao, Shuqi Ge, Xinru Yao, Chang Liu, Xintong Tan
    Molecules.2023; 28(13): 5132.     CrossRef
  • Distinct Organotypic Platforms Modulate Rainbow Trout (Oncorhynchus mykiss) Intestinal Cell Differentiation In Vitro
    Nicole Verdile, Federica Camin, Radmila Pavlovic, Rolando Pasquariello, Milda Stuknytė, Ivano De Noni, Tiziana A. L. Brevini, Fulvio Gandolfi
    Cells.2023; 12(14): 1843.     CrossRef
  • Activation of the 5-hydroxytryptamine 4 receptor ameliorates tight junction barrier dysfunction in the colon of type 1 diabetic mice
    Shasha Hu, Yueting Kou, Xiaochen Liu, Weifang Rong, Hongxiu Han, Guohua Zhang
    Acta Biochimica et Biophysica Sinica.2023; 55(12): 1874.     CrossRef
  • Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD): a condition exemplifying the crosstalk of the gut–liver axis
    You Sun Kim, Edward H. Hurley, Yoojeong Park, Sungjin Ko
    Experimental & Molecular Medicine.2023; 55(7): 1380.     CrossRef
  • A Supplement with Bromelain, Lentinula edodes, and Quercetin: Antioxidant Capacity and Effects on Morphofunctional and Fecal Parameters (Calprotectin, Cortisol, and Intestinal Fermentation Products) in Kennel Dogs
    David Atuahene, Annalisa Costale, Elisa Martello, Alessandro Mannelli, Elisabetta Radice, Davide Giuseppe Ribaldone, Biagina Chiofalo, Bruno Stefanon, Giorgia Meineri
    Veterinary Sciences.2023; 10(8): 486.     CrossRef
  • Injectable Bioadhesive Hydrogels Scavenging ROS and Restoring Mucosal Barrier for Enhanced Ulcerative Colitis Therapy
    Daming Li, Jiao Li, Tao Chen, Xianyan Qin, Lihua Pan, Xin Lin, Wenlang Liang, Qin Wang
    ACS Applied Materials & Interfaces.2023; 15(32): 38273.     CrossRef
  • Dietary supplementation of microalgae mitigates the negative effects of heat stress in broilers
    Ajay Chaudhary, Pravin Mishra, Sadid Al Amaz, Prem Lal Mahato, Razib Das, Rajesh Jha, Birendra Mishra
    Poultry Science.2023; 102(10): 102958.     CrossRef
  • Allulose enhances epithelial barrier function by tight junction regulation via the TLR4/MyD88/NF-κB immune signaling pathway in an intestinal Caco-2 cell model
    Jihye Baek, Jong-Hwa Kim, YoHan Nam, Go-Eun Kim, Kyungheon Ryu, Soonok Sa, Jung-Sook Han, Wonyong Kim
    Journal of Functional Foods.2023; 108: 105721.     CrossRef
  • Beneficial Effects of Lactobacilli Species on Intestinal Homeostasis in Low-Grade Inflammation and Stress Rodent Models and Their Implication in the Modulation of the Adhesive Junctional Complex
    Célia Chamignon, Geoffroy Mallaret, Julie Rivière, Marthe Vilotte, Sead Chadi, Alejandra de Moreno de LeBlanc, Jean Guy LeBlanc, Frédéric Antonio Carvalho, Marco Pane, Pierre-Yves Mousset, Philippe Langella, Sophie Lafay, Luis G. Bermúdez-Humarán
    Biomolecules.2023; 13(9): 1295.     CrossRef
  • Circadian rhythms in colonic function
    Timothy J. Hibberd, Stewart Ramsay, Phaedra Spencer-Merris, Phil G. Dinning, Vladimir P. Zagorodnyuk, Nick J. Spencer
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • Lactic Acid Bacteria Isolated from Human Breast Milk Improve Colitis Induced by 2,4,6-Trinitrobenzene Sulfonic Acid by Inhibiting NF-κB Signaling in Mice
    Kyung-Joo Kim, Suhyun Kyung, Hui Jin, Minju Im, Jae-won Kim, Hyun Su Kim, Se-Eun Jang
    Journal of Microbiology and Biotechnology.2023; 33(8): 1057.     CrossRef
  • Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice
    Lin Xiao, Weidong Dou, Yajie Wang, Huan Deng, Hao Xu, YiSheng Pan
    Biochemical Pharmacology.2023; 216: 115752.     CrossRef
  • Probiotic Properties and Safety Evaluation of Lactobacillus plantarum HY7718 with Superior Storage Stability Isolated from Fermented Squid
    Hyeonji Kim, Myeong-Seok Yoo, Hyejin Jeon, Jae-Jung Shim, Woo-Jung Park, Joo-Yun Kim, Jung-Lyoul Lee
    Microorganisms.2023; 11(9): 2254.     CrossRef
  • The Intertwining Roads between Psychological Distress and Gut Microbiota in Inflammatory Bowel Disease
    Georgiana-Emmanuela Gîlcă-Blanariu, Cristina Gabriela Șchiopu, Gabriela Ștefănescu, Cătălina Mihai, Smaranda Diaconescu, Vlad Adrian Afrăsânie, Vasile Valeriu Lupu, Ancuța Lupu, Alexandra Boloș, Cristinel Ștefănescu
    Microorganisms.2023; 11(9): 2268.     CrossRef
  • Dark Chocolate Intake Positively Modulates Gut Permeability in Elite Football Athletes: A Randomized Controlled Study
    Cristina Nocella, Elena Cavarretta, Chiara Fossati, Fabio Pigozzi, Federico Quaranta, Mariangela Peruzzi, Fabrizio De Grandis, Vincenzo Costa, Carwyn Sharp, Massimo Manara, Antonia Nigro, Vittoria Cammisotto, Valentina Castellani, Vittorio Picchio, Sebast
    Nutrients.2023; 15(19): 4203.     CrossRef
  • Role of the epithelial barrier in intestinal fibrosis associated with inflammatory bowel disease: relevance of the epithelial-to mesenchymal transition
    Dulce C. Macias-Ceja, M. Teresa Mendoza-Ballesteros, María Ortega-Albiach, M. Dolores Barrachina, Dolores Ortiz-Masià
    Frontiers in Cell and Developmental Biology.2023;[Epub]     CrossRef
  • Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells
    Masoumeh Sadat Mousavi Maleki, Hooman Aghamirza Moghim Ali Abadi, Behrooz Vaziri, Ali Akbar Shabani, Ghazaleh Ghavami, Hamid Madanchi, Soroush Sardari
    Amino Acids.2023; 55(11): 1601.     CrossRef
  • Lactobacillus plantarum ZJUIDS04 alleviates DSS-induced colitis via modulating gut microbiota
    Chongwei Yu, Jingtianyi Liu, Zonghao Liu, Qinchao Ding, Qinchao Zhu, Nan Chen, Jinfeng Fu, Teresa G. Valencak, Daxi Ren
    Journal of Functional Foods.2023; 109: 105794.     CrossRef
  • Profiling of the fecal microbiota and circulating microRNA-16 in IBS subjects with Blastocystis infection : a case–control study
    Alireza Olyaiee, Abbas Yadegar, Elnaz Sadat Mirsamadi, Amir Sadeghi, Hamed Mirjalali
    European Journal of Medical Research.2023;[Epub]     CrossRef
  • Effect of Extracelluar Vesicles Derived from Akkermansia muciniphila on Intestinal Barrier in Colitis Mice
    Ting Zheng, Haining Hao, Qiqi Liu, Jiankun Li, Yukun Yao, Yisuo Liu, Tai Zhang, Zhe Zhang, Huaxi Yi
    Nutrients.2023; 15(22): 4722.     CrossRef
  • Salivary concentrations of secretory leukocyte protease inhibitor and matrix metallopeptidase-9 following a single bout of exercise are associated with intensity and hydration status
    Karen Knipping, Shirley W. Kartaram, Marc Teunis, Nicolaas P. A. Zuithoff, Nicole Buurman, Laura M’Rabet, Klaske van Norren, Renger Witkamp, Raymond Pieters, Johan Garssen, David M. Ojcius
    PLOS ONE.2023; 18(11): e0291297.     CrossRef
  • Agaricus blazei Polysaccharide Alleviates DSS-Induced Colitis in Mice by Modulating Intestinal Barrier and Remodeling Metabolism
    Zhong-Hao Ji, Song He, Wen-Yin Xie, Pei-Sen Zhao, Wen-Zhi Ren, Wei Gao, Bao Yuan
    Nutrients.2023; 15(23): 4877.     CrossRef
  • The Contribution of the Intestinal Microbiota to the Celiac Disease Pathogenesis along with the Effectiveness of Probiotic Therapy
    Oxana Zolnikova, Natiya Dzhakhaya, Elena Bueverova, Alla Sedova, Anastasia Kurbatova, Kira Kryuchkova, Tatyana Butkova, Alexander Izotov, Ludmila Kulikova, Kseniya Yurku, Pavel Chekulaev, Victoria Zaborova
    Microorganisms.2023; 11(12): 2848.     CrossRef
  • Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells
    Weihua He, Jianhua Wang, Mengyi Han, Lihua Wang, Ling Li, Jiahui Zhang, Siqi Chen, Jiayi Guo, Xiaohu Zhai, Junhua Yang
    Toxins.2023; 15(12): 682.     CrossRef
  • Protective effects of different Bacteroides vulgatus strains against lipopolysaccharide-induced acute intestinal injury, and their underlying functional genes
    Chen Wang, Yue Xiao, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai
    Journal of Advanced Research.2022; 36: 27.     CrossRef
  • Homeostasis effects of fermented Maillard reaction products by Lactobacillus gasseri 4M13 in dextran sulfate sodium‐induced colitis mice
    Yu‐Jin Jeong, Da Hyun Kim, Kwang‐Won Lee
    Journal of the Science of Food and Agriculture.2022; 102(1): 434.     CrossRef
  • Enterococcus faecium HDRsEf1 inhibits Lipopolysaccharide‐induced downregulation of zona occludens ‐1 expression via toll‐like receptor 2/4‐mediated c‐Jun N‐terminal kinase/activator protein‐1 signalling pathways
    L. Liu, Y. Li, Y. He, Z. Wang, H. Zhao, X. Jin, D. Shi, X. Wang
    Journal of Applied Microbiology.2022; 132(1): 605.     CrossRef
  • Protection against indomethacin-induced loss of intestinal epithelial barrier function by a quercetin oxidation metabolite present in onion peel: In vitro and in vivo studies
    Jocelyn Fuentes, Oscar Brunser, Elías Atala, José Herranz, Adriano Costa de Camargo, Hermann Zbinden-Foncea, Hernán Speisky
    The Journal of Nutritional Biochemistry.2022; 100: 108886.     CrossRef
  • Effect of blending encapsulated essential oils and organic acids as an antibiotic growth promoter alternative on growth performance and intestinal health in broilers with necrotic enteritis
    Van Hieu Pham, Waseem Abbas, Jinyu Huang, Qiang He, Wenrui Zhen, Yuming Guo, Zhong Wang
    Poultry Science.2022; 101(1): 101563.     CrossRef
  • Modulation of Gut Barrier Functions in Ulcerative Colitis by Hyaluronic Acid System
    Niranjan G. Kotla, Isma Liza Mohd Isa, Swetha Rasala, Secil Demir, Rajbir Singh, Becca V. Baby, Samantha K. Swamy, Peter Dockery, Venkatakrishna R. Jala, Yury Rochev, Abhay Pandit
    Advanced Science.2022;[Epub]     CrossRef
  • Post-Cardiac Arrest Syndrome Is Not Associated With an Early Bacterial Translocation
    Eirini Filidou, Gesthimani Tarapatzi, Michail Spathakis, Panagiotis Papadopoulos, Charalampos Papadopoulos, Leonidas Kandilogiannakis, George Stavrou, Eleni Doumaki, Antonia Sioga, Soultana Meditskou, Konstantinos Arvanitidis, Theodora Papamitsou, Vassili
    Journal of Surgical Research.2022; 272: 51.     CrossRef
  • Re-aliment regains feed deprivation-induced microflora dysbiosis and immune stress in the gut of red swamp crayfish (Procambarus clarkii)
    Minglang Cai, Honghui Li, Xizhang Gu, Hongyan Tian, Fei Liu, Wenping Yang, Shengjie Ren, Wuying Chu, Yi Hu, Aimin Wang, Hongqin Li, Jiajia Li
    Aquaculture Reports.2022; 22: 100992.     CrossRef
  • Integrity of the Intestinal Barrier: The Involvement of Epithelial Cells and Microbiota—A Mutual Relationship
    Małgorzata Gieryńska, Lidia Szulc-Dąbrowska, Justyna Struzik, Matylda Barbara Mielcarska, Karolina Paulina Gregorczyk-Zboroch
    Animals.2022; 12(2): 145.     CrossRef
  • Supplementation of oligosaccharide-based polymer enhanced growth and disease resistance of weaned pigs by modulating intestinal integrity and systemic immunity
    Kwangwook Kim, Yijie He, Cynthia Jinno, Lauren Kovanda, Xunde Li, David Bravo, Eric Cox, Yanhong Liu
    Journal of Animal Science and Biotechnology.2022;[Epub]     CrossRef
  • Salvia miltiorrhiza Bge. (Danshen) for Inflammatory Bowel Disease: Clinical Evidence and Network Pharmacology-Based Strategy for Developing Supplementary Medical Application
    Siyuan Zhang, Hua Luo, Shiyi Sun, Yating Zhang, Jiaqi Ma, Yuting Lin, Lin Yang, Dechao Tan, Chaomei Fu, Zhangfeng Zhong, Yitao Wang
    Frontiers in Pharmacology.2022;[Epub]     CrossRef
  • The Intestinal Effect of Atorvastatin: Akkermansia muciniphila and Barrier Function
    Tingting Cheng, Changkun Li, Linyan Shen, Shujie Wang, Xuelin Li, Chenyang Fu, Tingting Li, Bei Liu, Yanyun Gu, Weiqing Wang, Bo Feng
    Frontiers in Microbiology.2022;[Epub]     CrossRef
  • Resveratrol alleviates aluminum‐induced intestinal barrier dysfunction in mice
    Wudi Hao, Xiaoying Zhu, Ziyue Liu, Yushuai Song, Shengwen Wu, Xiaobo Lu, Jinghua Yang, Cuihong Jin
    Environmental Toxicology.2022; 37(6): 1373.     CrossRef
  • Effects of encapsulated butyrate and salinomycin on gut leakage and intestinal inflammation in broilers
    M. Naghizadeh, T. S. Dalgaard, L. Klaver, R. M. Engberg
    British Poultry Science.2022; 63(4): 499.     CrossRef
  • Epigenetic modification in alcohol‐related liver diseases
    Amir Ajoolabady, Hamid Aslkhodapasandhokmabad, Yuan Zhou, Jun Ren
    Medicinal Research Reviews.2022; 42(4): 1463.     CrossRef
  • Intestinal barrier disorders and metabolic endotoxemia in obesity: Current knowledge
    Marta Potrykus, Michał Szymański, Łukasz Kaska, Agata Janczy
    Postępy Higieny i Medycyny Doświadczalnej.2022; 76(1): 71.     CrossRef
  • Resveratrol in Intestinal Health and Disease: Focusing on Intestinal Barrier
    Youxia Wang, Changming Hong, Zebiao Wu, Shuwei Li, Yaoyao Xia, Yuying Liang, Xiaohua He, Xinyu Xiao, Wenjie Tang
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • Effects of Caulis Spatholobi Polysaccharide on Immunity, Intestinal Mucosal Barrier Function, and Intestinal Microbiota in Cyclophosphamide-Induced Immunosuppressive Chickens
    Yao Cui, Wenjing Sun, Qinmei Li, Kaijun Wang, Yuhan Wang, Feifei Lv, Xiaogang Chen, Xiaomin Peng, Ying Wang, Jiang Li, Hongbin Si
    Frontiers in Veterinary Science.2022;[Epub]     CrossRef
  • An in vitro intestinal model captures immunomodulatory properties of the microbiota in inflammation
    Jaclyn Y. Lock, Mariaelena Caboni, Philip Strandwitz, Madeleine Morrissette, Kevin DiBona, Brian A. Joughin, Kim Lewis, Rebecca L. Carrier
    Gut Microbes.2022;[Epub]     CrossRef
  • The roles of catechins in regulation of systemic inflammation
    Jong Min Kim, Ho Jin Heo
    Food Science and Biotechnology.2022; 31(8): 957.     CrossRef
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    Yong Li, Ziheng Peng, Duo Xu, Yu Peng, Xiaowei Liu
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • Lactobacillus paracasei from koumiss ameliorates diarrhea in mice via tight junctions modulation
    Shunan Ren, Aorigele Chen, Yanping Tian, Zhaoxing Bai, Chunjie Wang
    Nutrition.2022; 98: 111584.     CrossRef
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    Abhinav Sharma, Vishnu Raman, Jungwoo Lee, Neil S. Forbes
    ACS Infectious Diseases.2022; 8(5): 969.     CrossRef
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    Bieke Vanslembrouck, Jian-hua Chen, Carolyn Larabell, Jolanda van Hengel
    Frontiers in Cell and Developmental Biology.2022;[Epub]     CrossRef
  • Modulation of microRNAs and claudin-7 in Caco-2 cell line treated with Blastocystis sp., subtype 3 soluble total antigen
    Hanieh Mohammad Rahimi, Abbas Yadegar, Hamid Asadzadeh Aghdaei, Hamed Mirjalali, Mohammad Reza Zali
    BMC Microbiology.2022;[Epub]     CrossRef
  • Stachyose protects intestinal mucosal barrier via promotion of tight junction and Lactobacillus casei-drived inhibition of apoptosis in juvenile turbot, Scophthalmus maximus L.
    Jihong Dai, Yanjiao Zhang, Weihao Ou, Guijuan Yu, Qinghui Ai, Wenbing Zhang, Kangsen Mai
    Aquaculture.2022; 556: 738280.     CrossRef
  • Intestinal Barrier Permeability in Allergic Diseases
    Monika Niewiem, Urszula Grzybowska-Chlebowczyk
    Nutrients.2022; 14(9): 1893.     CrossRef
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    Applied Sciences.2022; 12(9): 4680.     CrossRef
  • Modulating effects of a functional food containing Dendrobium officinale on immune response and gut microbiota in mice treated with cyclophosphamide
    Ying-Jie Dong, Min-Qiu Lin, Xi Fang, Zhi-Yi Xie, Rong Luo, Xi Teng, Bin Li, Bo Li, Lin-Zi Li, Hai-Ying Jin, Qiao-Xian Yu, Gui-Yuan Lv, Su-Hong Chen
    Journal of Functional Foods.2022; 94: 105102.     CrossRef
  • L-glutamine for sickle cell disease: more than reducing redox
    Firas Jafri, Gyuhee Seong, Tim Jang, Emanuela Cimpeanu, Maria Poplawska, Dibyendu Dutta, Seah H. Lim
    Annals of Hematology.2022; 101(8): 1645.     CrossRef
  • The Increase of miR-195-5p Reduces Intestinal Permeability in Ulcerative Colitis, Modulating Tight Junctions’ Expression
    Viviana Scalavino, Emanuele Piccinno, Giusy Bianco, Nicolò Schena, Raffaele Armentano, Gianluigi Giannelli, Grazia Serino
    International Journal of Molecular Sciences.2022; 23(10): 5840.     CrossRef
  • Ischemic stroke and intestinal flora: an insight into brain–gut axis
    Wenjie Hu, Xiangyi Kong, Hui Wang, Yunqing Li, Yimin Luo
    European Journal of Medical Research.2022;[Epub]     CrossRef
  • Protective Effects of Oxyberberine in 5-Fluorouracil-Induced Intestinal Mucositis in the Mice Model
    Ronglei Huang, Gaoxiang Ai, Linjiang Zhong, Liting Mai, Jian-Nan Chen, Yuhong Liu, Yucui Li, Xiaoqi Huang, Ziren Su, Janis Ya-Xian Zhan, Zewei Sun
    Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1.     CrossRef
  • Effects of Tannic Acid Supplementation on Growth Performance, Oocyst Shedding, and Gut Health of in Broilers Infected with Eimeria Maxima
    Janghan Choi, Yuguo Tompkins, Po-Yun Teng, Robert Gogal, Woo Kim
    Animals.2022; 12(11): 1378.     CrossRef
  • Incorporation of Fructooligosaccharides in Diets Influence Growth Performance, Digestive Enzyme Activity, and Expression of Intestinal Barrier Function Genes in Tropical Gar (Atractosteus tropicus) Larvae
    Graciela M. Pérez-Jiménez, Emyr Saul Peña-Marín, Claudia I. Maytorena-Verdugo, Cesar Antonio Sepúlveda-Quiroz, Luis Daniel Jiménez-Martínez, Susana De la Rosa-García, Gloria Gertrudys Asencio-Alcudia, Rafael Martínez, Dariel Tovar-Ramírez, Mario A. Galavi
    Fishes.2022; 7(3): 137.     CrossRef
  • Comparison of Selenium-Enriched Lactobacillusparacasei, Selenium-Enriched Yeast, and Selenite for the Alleviation of DSS-Induced Colitis in Mice
    Yuqing Zhong, Yan Jin, Qiuxiang Zhang, Bingyong Mao, Xin Tang, Jie Huang, Renmei Guo, Jianxin Zhao, Shumao Cui, Wei Chen
    Nutrients.2022; 14(12): 2433.     CrossRef
  • Lactobacillus acidophilus Supplementation Restores Gut Epithelial Integrities and Barrier Functions in Non-specific Diarrhea
    Hossain Ferdaus Mohd ALTAF, Sumaiya Islam FARZANA, Khan PARVEZ, Zahran EMAN, Atif Shaikh MUHAMMAD, Uddin Md NAZIM, Zinnah Kazi Mohammad ALİ, Khan IMDAD ULLAH, Rahman Md MASUDUR
    Journal of Microbiology and Infectious Diseases.2022; : 54.     CrossRef
  • Mechanisms of proton pump inhibitor‐induced hypomagnesemia
    Lisanne M. M. Gommers, Joost G. J. Hoenderop, Jeroen H. F. de Baaij
    Acta Physiologica.2022;[Epub]     CrossRef
  • Manipulation of Gut Microbiota as a Key Target for Crohn's Disease
    Reem Rashed, Rosica Valcheva, Levinus A. Dieleman
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment
    Shuo Yuan, Qi Wang, Jiao Li, Jia-Chen Xue, You Li, Huan Meng, Xiao-Ting Hou, Ji-Xing Nan, Qing-Gao Zhang
    Chinese Medicine.2022;[Epub]     CrossRef
  • Gut Microbiota-Derived Indole-3-Carboxylate Influences Mucosal Integrity and Immunity Through the Activation of the Aryl Hydrocarbon Receptors and Nutrient Transporters in Broiler Chickens Challenged With Eimeria maxima
    Inkyung Park, Hyoyoun Nam, Doyun Goo, Samiru S. Wickramasuriya, Noah Zimmerman, Alexandra H. Smith, Thomas G. Rehberger, Hyun S. Lillehoj
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Lactobacillus casei-fermented blueberry pomace ameliorates colonic barrier function in high fat diet mice through MAPK-NF-κB-MLCK signaling pathway
    Yuxin Cheng, Shuxin Tang, Ting Wu, Siyi Pan, Xiaoyun Xu
    Journal of Functional Foods.2022; 95: 105139.     CrossRef
  • Gut microbiome and autoimmune disorders
    Walaa Abdelaty Shaheen, Mohammed Nabil Quraishi, Tariq H Iqbal
    Clinical and Experimental Immunology.2022; 209(2): 161.     CrossRef
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    BioMed Research International.2022; 2022: 1.     CrossRef
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    Sweta Patel, Dipeeka Mandaliya, Sriram Seshadri
    Indian Journal of Microbiology.2022; 62(4): 540.     CrossRef
  • Role of CB1 receptors in the acute regulation of small intestinal permeability: effects of high-fat diet
    Hailey Cuddihey, Jean-Baptiste Cavin, Catherine M. Keenan, Laurie E. Wallace, Kiran Vemuri, Alexandros Makriyannis, Wallace K. MacNaughton, Keith A. Sharkey
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2022; 323(3): G219.     CrossRef
  • Roasted garlic protects against leaky gut syndrome in dextran sodium sulfate-induced colitis mice
    Divya Sharma, Madhuri Sangar, Jeom-Leon Park, Seong-Gook Kang, Kyung-Sik Ham
    Food Science and Biotechnology.2022; 31(10): 1335.     CrossRef
  • Role of the Endocannabinoid System in the Regulation of Intestinal Homeostasis
    Hailey Cuddihey, Wallace K. MacNaughton, Keith A. Sharkey
    Cellular and Molecular Gastroenterology and Hepatology.2022; 14(4): 947.     CrossRef
  • Ameliorating Effects of TRIM67 against Intestinal Inflammation and Barrier Dysfunction Induced by High Fat Diet in Obese Mice
    Qihui Luo, Asad Jahangir, Junbo He, Chao Huang, Yu Xia, Lanlan Jia, Xiaoli Wei, Ting Pan, Yanni Du, Bin Mu, Huan Gong, Wentao Liu, Saif Ur-Rehman, Kangcheng Pan, Zhengli Chen
    International Journal of Molecular Sciences.2022; 23(14): 7650.     CrossRef
  • Multiorgan‐on‐a‐chip for realization of gut‐skin axis
    Hye Ri Lee, Jong Hwan Sung
    Biotechnology and Bioengineering.2022; 119(9): 2590.     CrossRef
  • Sanhuang Xiexin decoction ameliorates DSS-induced colitis in mice by regulating intestinal inflammation, intestinal barrier, and intestinal flora
    Xueyuan Wu, Shu Fu, Miao Jiang, Jing Wang, Huaqiao Tang, Chunlin Fang, Wen Li, Chaomei Fu
    Journal of Ethnopharmacology.2022; 297: 115537.     CrossRef
  • Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease
    De-feng Li, Mei-feng Yang, Hao-ming Xu, Min-zheng Zhu, Yuan Zhang, Cheng-mei Tian, Yu-qiang Nie, Jian-yao Wang, Yu-jie Liang, Jun Yao, Li-sheng Wang
    Journal of Materials Chemistry B.2022; 10(31): 5853.     CrossRef
  • Comprehensive overview of COVID-19-related respiratory failure: focus on cellular interactions
    Fahimeh Zamani Rarani, Mohammad Zamani Rarani, Michael R. Hamblin, Bahman Rashidi, Seyed Mohammad Reza Hashemian, Hamed Mirzaei
    Cellular & Molecular Biology Letters.2022;[Epub]     CrossRef
  • Intestinal Osteopontin Protects From Alcohol-induced Liver Injury by Preserving the Gut Microbiome and the Intestinal Barrier Function
    Sukanta Das, Zhuolun Song, Hui Han, Xiaodong Ge, Romain Desert, Dipti Athavale, Sai Santosh Babu Komakula, Fernando Magdaleno, Wei Chen, Daniel Lantvit, Grace Guzman, Natalia Nieto
    Cellular and Molecular Gastroenterology and Hepatology.2022; 14(4): 813.     CrossRef
  • Pterostilbene attenuates intestinal epithelial barrier loss induced by high loading intensity of exercise
    Lidong Zhang, Guoliang Tian, Li Huang, Min Zhou, Jundong Zhu, Long Yi, Mantian Mi
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • Stem Cell-Based Therapies for Inflammatory Bowel Disease
    Hua-Min Zhang, Shuo Yuan, Huan Meng, Xiao-Ting Hou, Jiao Li, Jia-Chen Xue, You Li, Qi Wang, Ji-Xing Nan, Xue-Jun Jin, Qing-Gao Zhang
    International Journal of Molecular Sciences.2022; 23(15): 8494.     CrossRef
  • Sex-dependent Lupus Blautia (Ruminococcus) gnavus strain induction of zonulin-mediated intestinal permeability and autoimmunity
    Gregg J. Silverman, Jing Deng, Doua F. Azzouz
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Mannose ameliorates experimental colitis by protecting intestinal barrier integrity
    Lijun Dong, Jingwen Xie, Youyi Wang, Honglian Jiang, Kai Chen, Dantong Li, Jing Wang, Yunzhi Liu, Jia He, Jia Zhou, Liyun Zhang, Xiao Lu, Xiaoming Zou, Xiang-Yang Wang, Qingqing Wang, Zhengliang Chen, Daming Zuo
    Nature Communications.2022;[Epub]     CrossRef
  • Comparison of the Modulating Effect of Anthocyanin-Rich Sour Cherry Extract on Occludin and ZO-1 on Caco-2 and HUVEC Cultures
    Judit Remenyik, Attila Biró, Ágnes Klusóczki, Krisztián Zoltán Juhász, Tímea Szendi-Szatmári, Ádám Kenesei, Erzsébet Szőllősi, Gábor Vasvári, László Stündl, Ferenc Fenyvesi, Judit Váradi, Arnold Markovics
    International Journal of Molecular Sciences.2022; 23(16): 9036.     CrossRef
  • Regulatory Effect of Isomaltodextrin on a High-Fat Diet Mouse Model with LPS-Induced Low-Grade Chronic Inflammation
    Yijun Liu, Yuhan Zeng, Yixin Liu, Xiaoya Wang, Yuhuan Chen, Dion Lepp, Rong Tsao, Tsuyoshi Sadakiyo, Hua Zhang, Yoshinori Mine
    Journal of Agricultural and Food Chemistry.2022; 70(36): 11258.     CrossRef
  • Hemp-Derived Nanovesicles Protect Leaky Gut and Liver Injury in Dextran Sodium Sulfate-Induced Colitis
    Jung-Young Eom, Sang-Hun Choi, Hyun-Jin Kim, Dong-ha Kim, Ju-Hyun Bae, Gi-Seok Kwon, Dong-hee Lee, Jin-Hyeon Hwang, Do-Kyun Kim, Moon-Chang Baek, Young-Eun Cho
    International Journal of Molecular Sciences.2022; 23(17): 9955.     CrossRef
  • Bifidobacterium breve Alleviates DSS-Induced Colitis in Mice by Maintaining the Mucosal and Epithelial Barriers and Modulating Gut Microbes
    Meng-Meng Niu, Huan-Xin Guo, Jun-Wu Cai, Xiang-Chen Meng
    Nutrients.2022; 14(18): 3671.     CrossRef
  • High Molecular Weight Fucoidan Restores Intestinal Integrity by Regulating Inflammation and Tight Junction Loss Induced by Methylglyoxal-Derived Hydroimidazolone-1
    Jae-Min Lim, Hee Joon Yoo, Kwang-Won Lee
    Marine Drugs.2022; 20(9): 580.     CrossRef
  • Traditional Chinese Medicine and Natural Products: Potential Approaches for Inflammatory Bowel Disease
    Shuo Yuan, You Li, Jiao Li, Jia-Chen Xue, Qi Wang, Xiao-Ting Hou, Huan Meng, Ji-Xing Nan, Qing-Gao Zhang
    Frontiers in Pharmacology.2022;[Epub]     CrossRef
  • P2X7 receptor as the regulator of T-cell function in intestinal barrier disruption
    Zhi-Feng Jiang, Wei Wu, Han-Bing Hu, Zheng-Yang Li, Ming Zhong, Lin Zhang
    World Journal of Gastroenterology.2022; 28(36): 5265.     CrossRef
  • Gut dysfunction may be the source of pathological aggregation of alpha-synuclein in the central nervous system through Paraquat exposure in mice
    Kaidong Wang, Chunhui Zhang, Baofu Zhang, Guoliang Li, Ge Shi, Qian Cai, Min Huang
    Ecotoxicology and Environmental Safety.2022; 246: 114152.     CrossRef
  • Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7
    Ying Xiao, Haifeng Lian, Xiaoying S. Zhong, Srikruthi S. Krishnachaitanya, Yingzi Cong, Roderick H. Dashwood, Tor C. Savidge, Don W. Powell, Xiaowei Liu, Qingjie Li
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Pretreatment with probiotics Enterococcus faecium NCIMB 11181 attenuated Salmonella Typhimurium-induced gut injury through modulating intestinal microbiome and immune responses with barrier function in broiler chickens
    Yujing Shao, Wenrui Zhen, Fangshen Guo, Zeqiong Hu, Kaichen Zhang, Linhua Kong, Yuming Guo, Zhong Wang
    Journal of Animal Science and Biotechnology.2022;[Epub]     CrossRef
  • Interaction and toxicity of ingested nanoparticles on the intestinal barrier
    Thomas Stalder, Taghrid Zaiter, Wassim El-Basset, Raphaël Cornu, Hélène Martin, Mona Diab-Assaf, Arnaud Béduneau
    Toxicology.2022; 481: 153353.     CrossRef
  • Investigation of murine host sex as a biological variable in epithelial barrier function and muscle contractility in human intestinal organoids
    Brooke T. Beanland, Eoin P. McNeill, David J. Sequeira, Hasen Xue, Noah F. Shroyer, Allison L. Speer
    The FASEB Journal.2022;[Epub]     CrossRef
  • Thiamine Supplementation Alleviates Lipopolysaccharide-Triggered Adaptive Inflammatory Response and Modulates Energy State via Suppression of NFκB/p38 MAPK/AMPK Signaling in Rumen Epithelial Cells of Goats
    Yi Ma, Mawda Elmhadi, Chao Wang, Zelin Li, Hao Zhang, Banglin He, Xiujuan Zhao, Zhenbin Zhang, Hongrong Wang
    Antioxidants.2022; 11(10): 2048.     CrossRef
  • Inflammation and Impaired Gut Physiology in Post-operative Ileus: Mechanisms and the Treatment Options
    Zahid Hussain, Hyojin Park
    Journal of Neurogastroenterology and Motility.2022; 28(4): 517.     CrossRef
  • Senegalia macrostachya seed polysaccharides attenuate inflammation-induced intestinal epithelial barrier dysfunction in a Caco-2 and RAW264.7 macrophage co-culture model by inhibiting the NF-κB/MLCK pathway
    Abel Wend-Soo Zongo, Daniel Zogona, Mahmoud Youssef, Shuxin Ye, Fuchao Zhan, Jing Li, Bin Li
    Food & Function.2022; 13(22): 11676.     CrossRef
  • Zearalenone-Induced Mechanical Damage of Intestinal Barrier via the RhoA/ROCK Signaling Pathway in IPEC-J2 Cells
    Biying Huang, Jingjing Wang, Aixin Gu, Tianhu Wang, Jianping Li, Anshan Shan
    International Journal of Molecular Sciences.2022; 23(20): 12550.     CrossRef
  • A Review of the Chemistry and Biological Activities of Acmella oleracea (“jambù”, Asteraceae), with a View to the Development of Bioinsecticides and Acaricides
    Eleonora Spinozzi, Marta Ferrati, Cecilia Baldassarri, Loredana Cappellacci, Margherita Marmugi, Alice Caselli, Giovanni Benelli, Filippo Maggi, Riccardo Petrelli
    Plants.2022; 11(20): 2721.     CrossRef
  • The Importance of Nutritional Aspects in the Assessment of Inflammation and Intestinal Barrier in Patients with Inflammatory Bowel Disease
    Olga Kaczmarczyk, Agnieszka Dąbek-Drobny, Agnieszka Piątek-Guziewicz, Michał Woźniakiewicz, Paweł Paśko, Justyna Dobrowolska-Iwanek, Aneta Woźniakiewicz, Aneta Targosz, Agata Ptak-Belowska, Urszula Szczyrk, Małgorzata Strzałka, Paweł Zagrodzki, Małgorzata
    Nutrients.2022; 14(21): 4622.     CrossRef
  • Insight into role of short chain fatty acids in regulating intestinal mucosal barrier and alleviating inflammatory bowel disease
    Xue-Ran Guo, Cheng-Wei He, Han Gao, Rong-Xuan Hua, Chen Liang, Yi-Xuan Du, Hong-Wei Shang, Xin Lu, Jing-Dong Xu
    World Chinese Journal of Digestology.2022; 30(21): 928.     CrossRef
  • Metabolites of Latilactobacillus curvatus BYB3 and Indole Activate Aryl Hydrocarbon Receptor to Attenuate Lipopolysaccharide-Induced Intestinal Barrier Dysfunction
    Xing Wang, Cheng Chung Yong, Sejong Oh
    Food Science of Animal Resources.2022; 42(6): 1046.     CrossRef
  • Microbiota Dysbiosis and Gut Barrier Dysfunction Associated with Non-Alcoholic Fatty Liver Disease Are Modulated by a Specific Metabolic Cofactors’ Combination
    Sergio Quesada-Vázquez, Caitlin Bone, Shikha Saha, Iris Triguero, Marina Colom-Pellicer, Gerard Aragonès, Falk Hildebrand, Josep M. del Bas, Antoni Caimari, Naiara Beraza, Xavier Escoté
    International Journal of Molecular Sciences.2022; 23(22): 13675.     CrossRef
  • Proteomics analysis reveals novel insights into the mechanism of hepatotoxicity induced by Tripterygium wilfordii multiglycoside in mice
    Yingying Miao, Qin Zhang, Zihang Yuan, Jie Wang, Yunxia Xu, Yuanyuan Chai, Min Du, Qinwei Yu, Luyong Zhang, Zhenzhou Jiang
    Frontiers in Pharmacology.2022;[Epub]     CrossRef
  • The Effects of Dietary Bacillus amyloliquefaciens TL106 Supplementation, as an Alternative to Antibiotics, on Growth Performance, Intestinal Immunity, Epithelial Barrier Integrity, and Intestinal Microbiota in Broilers
    Chengling Bao, Wenxiu Zhang, Jian Wang, Yajing Liu, Heng Cao, Feiyu Li, Suozhu Liu, Zhengda Shang, Yunhe Cao, Bing Dong
    Animals.2022; 12(22): 3085.     CrossRef
  • Effect of dietary oregano oil on growth performance, disease resistance, intestinal morphology, immunity, and microbiota of hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂)
    Yu Xin, Hao Liu, Xiaobo Yan, Weibin Huang, Simiao Pan, Menglong Zhou, Baiquan Lu, Beiping Tan, Xiaohui Dong, Yuanzhi Yang
    Frontiers in Marine Science.2022;[Epub]     CrossRef
  • Comparison between Lactobacillus rhamnosus GG and LuxS-deficient strain in regulating gut barrier function and inflammation in early-weaned piglets
    Zhaoxi Deng, Jinyan Dai, Yusen Wei, Yanfei Ma, Yingying Mao, Jinzhi Zhang, Weidong Hua, Haifeng Wang
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Influence of Effective Microorganisms and Clinoptilolite on Gut Barrier Function, Intestinal Health and Performance of Broiler Chickens during Induced Eimeria tenella Infection
    Artur Ciszewski, Łukasz S. Jarosz, Marcin Kalinowski, Agnieszka Marek, Zbigniew Grądzki, Sebastian Grabowski, Marcin Hejdysz, Sebastian Nowaczewski, Anna Rysiak
    Agriculture.2022; 12(12): 2176.     CrossRef
  • A food pyramid, based on a review of the emerging literature, for subjects with inflammatory bowel disease
    Mariangela Rondanelli, Silvia Lamburghini, Milena A. Faliva, Gabriella Peroni, Antonella Riva, Pietro Allegrini, Daniele Spadaccini, Clara Gasparri, Giancarlo Iannello, Vittoria Infantino, Tariq A. Alalwan, Simone Perna, Alessandra Miccono
    Endocrinología, Diabetes y Nutrición.2021; 68(1): 17.     CrossRef
  • LncRNA: A Potential Research Direction in Intestinal Barrier Function
    Zhi-Feng Jiang, Lin Zhang
    Digestive Diseases and Sciences.2021; 66(5): 1400.     CrossRef
  • Site‐specific contribution of Toll‐like receptor 4 to intestinal homeostasis and inflammatory disease
    Elise E. Bruning, Janet K. Coller, Hannah R. Wardill, Joanne M. Bowen
    Journal of Cellular Physiology.2021; 236(2): 877.     CrossRef
  • Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders
    Charlotte A. Alemao, Kurtis F. Budden, Henry M. Gomez, Saima F. Rehman, Jacqueline E. Marshall, Shakti D. Shukla, Chantal Donovan, Samuel C. Forster, Ian A. Yang, Simon Keely, Elizabeth R. Mann, Emad M. El Omar, Gabrielle T. Belz, Philip M. Hansbro
    Allergy.2021; 76(3): 714.     CrossRef
  • One‐Pot Synthesis of pH‐Responsive Eudragit‐Mesoporous Silica Nanocomposites Enable Colonic Delivery of Glucocorticoids for the Treatment of Inflammatory Bowel Disease
    Zhi Qu, Kuan Yau Wong, Md. Moniruzzaman, Jakob Begun, Hélder A Santos, Sumaira Z. Hasnain, Tushar Kumeria, Michael A. McGuckin, Amirali Popat
    Advanced Therapeutics.2021;[Epub]     CrossRef
  • In Vivo Transplantation of Human Intestinal Organoids Enhances Select Tight Junction Gene Expression
    Mariaelena A. Boyle, David J. Sequeira, Eoin P. McNeill, Zachary K. Criss, Noah F. Shroyer, Allison L. Speer
    Journal of Surgical Research.2021; 259: 500.     CrossRef
  • Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1
    Xin Zong, Xiao Xiao, Lixia Kai, Yuanzhi Cheng, Jie Fu, Wei Xu, Yizhen Wang, Ke Zhao, Mingliang Jin
    International Journal of Biological Macromolecules.2021; 167: 76.     CrossRef
  • Dose-dependent effects of lead induced gut injuries: An in vitro and in vivo study
    Leilei Yu, Yaqi Yu, Ruijie Yin, Hui Duan, Dingwu Qu, Fengwei Tian, Arjan Narbad, Wei Chen, Qixiao Zhai
    Chemosphere.2021; 266: 129130.     CrossRef
  • A Novel Role of SLC26A3 in the Maintenance of Intestinal Epithelial Barrier Integrity
    Anoop Kumar, Shubha Priyamvada, Yong Ge, Dulari Jayawardena, Megha Singhal, Arivarasu N. Anbazhagan, Ishita Chatterjee, Aneal Dayal, Mitul Patel, Kimia Zadeh, Seema Saksena, Waddah A. Alrefai, Ravinder K. Gill, Mojgan Zadeh, Ni Zhao, Mansour Mohamadzadeh,
    Gastroenterology.2021; 160(4): 1240.     CrossRef
  • Vancomycin-Induced Changes in Host Immunity and Behavior: Comparative Genomic and Metagenomic Analysis in C57BL/6 and BALB/c Mice
    Pratikshya Ray, Uday Pandey, Debasmita Das, Palok Aich
    Digestive Diseases and Sciences.2021; 66(11): 3776.     CrossRef
  • Thermal or membrane processing for Infant Milk Formula: Effects on protein digestion and integrity of the intestinal barrier
    Simona L. Bavaro, Gianfranco Mamone, Gianluca Picariello, Michael J. Callanan, Yihong Chen, André Brodkorb, Linda Giblin
    Food Chemistry.2021; 347: 129019.     CrossRef
  • Plumericin Protects against Experimental Inflammatory Bowel Disease by Restoring Intestinal Barrier Function and Reducing Apoptosis
    Shara Francesca Rapa, Rosanna Di Paola, Marika Cordaro, Rosalba Siracusa, Ramona D’Amico, Roberta Fusco, Giuseppina Autore, Salvatore Cuzzocrea, Hermann Stuppner, Stefania Marzocco
    Biomedicines.2021; 9(1): 67.     CrossRef
  • Intestinal changes associated with fluoride exposure in rats: Integrative morphological, proteomic and microbiome analyses
    Aline Dionizio, Dawud Abduweli Uyghurturk, Carina Guimarães Souza Melo, Isabela Tomazini Sabino-Arias, Tamara Teodoro Araujo, Talita Mendes Silva Ventura, Juliana Vanessa Colombo Martins Perles, Jacqueline Nelisis Zanoni, Pamela Den Besten, Marília Afonso
    Chemosphere.2021; 273: 129607.     CrossRef
  • Effect of rifaximin on gut-lung axis in mice infected with influenza A virus
    Yafei Chen, Zuoyi Jiang, Zhihai Lei, Jihui Ping, Juan Su
    Comparative Immunology, Microbiology and Infectious Diseases.2021; 75: 101611.     CrossRef
  • Microbiota‐derived extracellular vesicles and metabolic syndrome
    Alexandre Villard, Jérôme Boursier, Ramaroson Andriantsitohaina
    Acta Physiologica.2021;[Epub]     CrossRef
  • Development of an in vitro coculture device for the investigation of host–microbe interactions via integrative multiomics approaches
    Won‐Suk Song, Sung Gyu Shin, Sung‐Hyun Jo, Jae‐Seung Lee, Hyo‐Jin Jeon, Ji‐Eun Kwon, Ji‐Hyeon Park, Sungwoo Cho, Jae Hyun Jeong, Byung‐Gee Kim, Yun‐Gon Kim
    Biotechnology and Bioengineering.2021; 118(4): 1593.     CrossRef
  • The role of inflammatory cytokines in anemia and gastrointestinal mucosal injury induced by foot electric stimulation
    Fangcheng Fan, Yangwen Ai, Ting Sun, Shuran Li, Hua Liu, Xiaojie Shi, Ziqian Zhang, Qingshan Liu, Yong Cheng
    Scientific Reports.2021;[Epub]     CrossRef
  • Organ-Specific Surveillance and Long-Term Residency Strategies Adapted by Tissue-Resident Memory CD8+ T Cells
    Jens V. Stein, Nora Ruef, Stefanie Wissmann
    Frontiers in Immunology.2021;[Epub]     CrossRef
  • Quercetin Oxidation Metabolite Present in Onion Peel Protects Caco-2 Cells against the Oxidative Stress, NF-kB Activation, and Loss of Epithelial Barrier Function Induced by NSAIDs
    Jocelyn Fuentes, Adriano Costa de Camargo, Elías Atala, Martín Gotteland, Claudio Olea-Azar, Hernán Speisky
    Journal of Agricultural and Food Chemistry.2021; 69(7): 2157.     CrossRef
  • Gut microbiome, prebiotics, intestinal permeability and diabetes complications
    Matthew Snelson, Cassandra de Pasquale, Elif I. Ekinci, Melinda T. Coughlan
    Best Practice & Research Clinical Endocrinology & Metabolism.2021; 35(3): 101507.     CrossRef
  • Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis
    Jacob P. Veenstra, Bhaskar Vemu, Restituto Tocmo, Mirielle C. Nauman, Jeremy J. Johnson
    Nutrients.2021; 13(3): 773.     CrossRef
  • Protective effect of exopolysaccharide fraction from Bacillus subtilis against dextran sulfate sodium-induced colitis through maintenance of intestinal barrier and suppression of inflammatory responses
    Kyung-Sook Chung, Ji-Sun Shin, Jung-Hun Lee, Sang-Eun Park, Hee-Soo Han, Young Kyoung Rhee, Chang-Won Cho, Hee-Do Hong, Kyung-Tae Lee
    International Journal of Biological Macromolecules.2021; 178: 363.     CrossRef
  • Polysaccharides in natural products that repair the damage to intestinal mucosa caused by cyclophosphamide and their mechanisms: A review
    Cuiping Li, Shasha Duan, Yaping Li, Xiao Pan, Lirong Han
    Carbohydrate Polymers.2021; 261: 117876.     CrossRef
  • A food pyramid, based on a review of the emerging literature, for subjects with inflammatory bowel disease
    Mariangela Rondanelli, Silvia Lamburghini, Milena A. Faliva, Gabriella Peroni, Antonella Riva, Pietro Allegrini, Daniele Spadaccini, Clara Gasparri, Giancarlo Iannello, Vittoria Infantino, Tariq A. Alalwan, Simone Perna, Alessandra Miccono
    Endocrinología, Diabetes y Nutrición (English ed.).2021; 68(1): 17.     CrossRef
  • Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease
    Robin M. Voigt, Shohreh Raeisi, Jingyun Yang, Sue Leurgans, Christopher B. Forsyth, Aron S. Buchman, David A. Bennett, Ali Keshavarzian, Stephen D. Ginsberg
    PLOS ONE.2021; 16(3): e0240342.     CrossRef
  • Microbiota, renal disease and renal transplantation
    Maurizio Salvadori, Aris Tsalouchos
    World Journal of Transplantation.2021; 11(3): 16.     CrossRef
  • Herbal medicine WangShiBaoChiWan improves gastrointestinal health in mice via modulation of intestinal tight junctions and gut microbiota and inhibition of inflammation
    Sheng Yin, Chao Sun, Yi Ji, Hamid Abdolmaleky, Jin-Rong Zhou
    Biomedicine & Pharmacotherapy.2021; 138: 111426.     CrossRef
  • Supplementation of milk polar lipids to obese dams improves neurodevelopment and cognitive function in male offspring
    Qi‐chen Yuan, Han Gong, Min Du, Xue‐ying Mao
    The FASEB Journal.2021;[Epub]     CrossRef
  • Potential mechanistic pathways underlying intestinal and hepatic effects of kefir in high-fructose-fed rats
    Fatma Akar, Esra Sumlu, Mehmet Eray Alçığır, Aykut Bostancı, Gökhan Sadi
    Food Research International.2021; 143: 110287.     CrossRef
  • Evaluation of the efficacy of probiotic VSL#3 and synbiotic VSL#3 and yacon‐based product in reducing oxidative stress and intestinal permeability in mice induced to colorectal carcinogenesis
    Bruna Cristina dos Santos Cruz, Luís Fernando de Sousa Moraes, Letícia De Nadai Marcon, Kelly Aparecida Dias, Leonardo Borges Murad, Mariáurea Matias Sarandy, Lisiane Lopes da Conceição, Reggiani Vilela Gonçalves, Célia Lúcia de Luces Fortes Ferreira, Mar
    Journal of Food Science.2021; 86(4): 1448.     CrossRef
  • Anethole Attenuates Enterotoxigenic Escherichia coli-Induced Intestinal Barrier Disruption and Intestinal Inflammation via Modification of TLR Signaling and Intestinal Microbiota
    Qingyuan Yi, Jiaxin Liu, Yufeng Zhang, Hanzhen Qiao, Fang Chen, Shihai Zhang, Wutai Guan
    Frontiers in Microbiology.2021;[Epub]     CrossRef
  • The effect of hypergravity in intestinal permeability of nanoformulations and molecules
    Cláudia Azevedo, Maria Helena Macedo, Andreia Almeida, Soraia Pinto, Jack J.W.A. van Loon, Bruno Sarmento
    European Journal of Pharmaceutics and Biopharmaceutics.2021; 163: 38.     CrossRef
  • Dietary supplementation of dried plum: a novel strategy to mitigate heat stress in broiler chickens
    Sanjeev Wasti, Nirvay Sah, Amit K. Singh, Chin N. Lee, Rajesh Jha, Birendra Mishra
    Journal of Animal Science and Biotechnology.2021;[Epub]     CrossRef
  • Antiviral Properties of Human Milk
    Sophie I. S. Wedekind, Natalie S. Shenker
    Microorganisms.2021; 9(4): 715.     CrossRef
  • Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR‐miR‐429 pathway
    Yuyao Chu, Yanrong Zhu, Yajing Zhang, Xiaojing Liu, Yilei Guo, Lan Chang, Xinming Yun, Zhifeng Wei, Yufeng Xia, Yue Dai
    The FASEB Journal.2021;[Epub]     CrossRef
  • Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF‐κB pathway suppression in porcine intestinal epithelial cells
    Xiaobo Guo, Jun Chen, Jin Yang, Qin He, Bowen Luo, Yafei Lu, Tiande Zou, Zirui Wang, Jinming You
    Journal of Animal Physiology and Animal Nutrition.2021; 105(6): 1063.     CrossRef
  • Dietary Fiber Ameliorates Lipopolysaccharide-Induced Intestinal Barrier Function Damage in Piglets by Modulation of Intestinal Microbiome
    Xiao Sun, Yalei Cui, Yingying Su, Zimin Gao, Xinying Diao, Ju Li, Xiaoyan Zhu, Defeng Li, Zhentian Li, Chengzhang Wang, Yinghua Shi, Hiutung Chu
    mSystems.2021;[Epub]     CrossRef
  • Butyrate-producing human gut symbiont, Clostridium butyricum, and its role in health and disease
    Magdalena K. Stoeva, Jeewon Garcia-So, Nicholas Justice, Julia Myers, Surabhi Tyagi, Madeleine Nemchek, Paul J. McMurdie, Orville Kolterman, John Eid
    Gut Microbes.2021;[Epub]     CrossRef
  • A Novel Role of A2AR in the Maintenance of Intestinal Barrier Function of Enteric Glia from Hypoxia-Induced Injury by Combining with mGluR5
    Lihua Sun, Xiang Li, Haidi Guan, Shuaishuai Chen, Xin Fan, Chao Zhou, Hua Yang, Weidong Xiao
    Frontiers in Pharmacology.2021;[Epub]     CrossRef
  • Gut microbiota mediated the protective effects of tuna oil on collagen-induced arthritis in mice
    Chenyang Lu, Ju Chen, Congmin Yi, Jiaojiao Han, Qiuyue Shi, Jingjing Li, Bing Liu, Jun Zhou, Xiurong Su
    Food & Function.2021; 12(12): 5387.     CrossRef
  • Nuciferine improves high-fat diet-induced obesity via reducing intestinal permeability by increasing autophagy and remodeling the gut microbiota
    Zhen Shi, Zhi-yuan Fang, Xin-xing Gao, Hao Yu, Yi-wei Zhu, Hui-lin Ouyang, Yu-xiang Song, Xi-liang Du, Zhe Wang, Xin-wei Li, Guo-wen Liu
    Food & Function.2021; 12(13): 5850.     CrossRef
  • Gut microbiome-host interactions in driving environmental pollutant trichloroethene-mediated autoimmunity
    Hui Wang, Nivedita Banerjee, Yuejin Liang, Gangduo Wang, Kristi L. Hoffman, M. Firoze Khan
    Toxicology and Applied Pharmacology.2021; 424: 115597.     CrossRef
  • Tilapia head glycolipids protect mice against dextran sulfate sodium-induced colitis by ameliorating the gut barrier and suppressing NF-kappa B signaling pathway
    Zhipeng Gu, Yujie Zhu, Fengfeng Mei, Xiuping Dong, Guanghua Xia, Xuanri Shen
    International Immunopharmacology.2021; 96: 107802.     CrossRef
  • Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis
    Xiaohui Yuan, Chen Luo, Jun Wu, Wei Li, Xin Guo, Shuai Li, Bing Wang, Hongyu Sun, Lijun Tang
    Experimental Biology and Medicine.2021; 246(18): 2029.     CrossRef
  • Corni fructus Extracts of Prebiotics Property and Cell Protective Effect on LPS-Induced Human Colon Epithelial Cell
    Hyo Lim Lee, Uk Lee, Seon Kyeong Park, Jin Yong Kang, Jong Min Kim, Gil Han Kim, Min Ji Kim, Jong Hyun Moon, Hye Rin Jeong, Hyo Won Park, Ho Jin Heo
    Journal of the Korean Society of Food Science and Nutrition.2021; 50(5): 445.     CrossRef
  • Lactobacillus ruminis Alleviates DSS-Induced Colitis by Inflammatory Cytokines and Gut Microbiota Modulation
    Bo Yang, Mingjie Li, Shuo Wang, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang, Wei Chen
    Foods.2021; 10(6): 1349.     CrossRef
  • Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells
    Yuhang Jin, Zhian Zhai, Hai Jia, Jinhua Lai, Xuemeng Si, Zhenlong Wu
    Food & Function.2021; 12(15): 6889.     CrossRef
  • Effects of Wine and Its Microbial-Derived Metabolites on Intestinal Permeability Using Simulated Gastrointestinal Digestion/Colonic Fermentation and Caco-2 Intestinal Cell Models
    Irene Zorraquín-Peña, Diego Taladrid, Alba Tamargo, Mariana Silva, Natalia Molinero, Dolores González de Llano, Begoña Bartolomé, M. Victoria Moreno-Arribas
    Microorganisms.2021; 9(7): 1378.     CrossRef
  • Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model
    Li Gu, Feng Ren, Xianrui Fang, Lianwen Yuan, Ganglei Liu, Shalong Wang
    Frontiers in Medicine.2021;[Epub]     CrossRef
  • Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets
    Chunyan Xie, Yumei Zhang, Kaimin Niu, Xiaoxiao Liang, Haihua Wang, Junwei Shan, Xin Wu
    Animal Nutrition.2021; 7(3): 641.     CrossRef
  • Therapeutic effect of Schisandrin A on avian colibacillosis through gut-liver axis
    Jialu Bao, Yan Zhang, Linchao Zhang, Xincheng Gong, Wanyu Shi, Liantao Liu, Xiaodan Wang
    Poultry Science.2021; 100(10): 101371.     CrossRef
  • Somatostatin receptor 5 is critical for protecting intestinal barrier function in vivo and in vitro
    Yanni Li, Xiao Li, Chong Geng, Yaoyu Guo, Chunhui Wang
    Molecular and Cellular Endocrinology.2021; 535: 111390.     CrossRef
  • Small and Large Intestine (II): Inflammatory Bowel Disease, Short Bowel Syndrome, and Malignant Tumors of the Digestive Tract
    Yolanda Ber, Santiago García-Lopez, Carla J. Gargallo-Puyuelo, Fernando Gomollón
    Nutrients.2021; 13(7): 2325.     CrossRef
  • Role of microbiota and related metabolites in gastrointestinal tract barrier function in NAFLD
    Maria Victoria Fernandez-Cantos, Diego Garcia-Morena, Valeria Iannone, Hani El-Nezami, Marjukka Kolehmainen, Oscar P. Kuipers
    Tissue Barriers.2021;[Epub]     CrossRef
  • Bioavailability of arsenic, cadmium, lead and mercury as measured by intestinal permeability
    Shiv Bolan, Balaji Seshadri, Simon Keely, Anitha Kunhikrishnan, Jessica Bruce, Ian Grainge, Nicholas J. Talley, Ravi Naidu
    Scientific Reports.2021;[Epub]     CrossRef
  • Neutrophil extracellular traps in inflammatory bowel diseases: Implications in pathogenesis and therapeutic targets
    Anderson dos Santos Ramos, Giovana Cristina Santana Viana, Marcelo de Macedo Brigido, Juliana Franco Almeida
    Pharmacological Research.2021; 171: 105779.     CrossRef
  • Dietary supplementation of alpha-lipoic acid mitigates the negative effects of heat stress in broilers
    Sanjeev Wasti, Nirvay Sah, Chin N. Lee, Rajesh Jha, Birendra Mishra, Arda Yildirim
    PLOS ONE.2021; 16(7): e0254936.     CrossRef
  • Probiotic Supplementation for Rheumatoid Arthritis: A Promising Adjuvant Therapy in the Gut Microbiome Era
    Margarida Ferro, Sofia Charneca, Eduardo Dourado, Catarina Sousa Guerreiro, João Eurico Fonseca
    Frontiers in Pharmacology.2021;[Epub]     CrossRef
  • Prebiotic, Probiotic, and Synbiotic Consumption Alter Behavioral Variables and Intestinal Permeability and Microbiota in BTBR Mice
    Jodi E. Nettleton, Teja Klancic, Alana Schick, Ashley C. Choo, Ning Cheng, Jane Shearer, Stephanie L. Borgland, Jong M. Rho, Raylene A. Reimer
    Microorganisms.2021; 9(9): 1833.     CrossRef
  • Enzyme-Treated Soybean Meal Enhanced Performance via Improving Immune Response, Intestinal Morphology and Barrier Function of Nursery Pigs in Antibiotic Free Diets
    Shenfei Long, Jiayu Ma, Xiangshu Piao, Yuxin Li, Simone Husballe Rasmussen, Li Liu
    Animals.2021; 11(9): 2600.     CrossRef
  • The preventive effect and underlying mechanism ofRhus chinensisMill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice
    Yi Zhang, Ou Wang, Nan Ma, Junjie Yi, Hongying Mi, Shengbao Cai
    Food & Function.2021; 12(20): 9965.     CrossRef
  • Ferulic Acid Metabolites Attenuate LPS-Induced Inflammatory Response in Enterocyte-like Cells
    Gabriele Serreli, Micaela Rita Naitza, Sonia Zodio, Vera Piera Leoni, Martina Spada, Maria Paola Melis, Anna Boronat, Monica Deiana
    Nutrients.2021; 13(9): 3152.     CrossRef
  • Ageratina adenophora Disrupts the Intestinal Structure and Immune Barrier Integrity in Rats
    Yujing Cui, Samuel Kumi Okyere, Pei Gao, Juan Wen, Suizhong Cao, Ya Wang, Junliang Deng, Yanchun Hu
    Toxins.2021; 13(9): 651.     CrossRef
  • PLP2 drives collective cell migration via ZO-1-mediated cytoskeletal remodeling at the leading edge in human colorectal cancer cells
    Dipanjana Ghosh, Ankita Dutta, Anjali Kashyap, Neeraj Upmanyu, Sunando Datta
    Journal of Cell Science.2021;[Epub]     CrossRef
  • A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age
    Rachel H. McMahan, Kevin M. Najarro, Juliet E. Mullen, Madison T. Paul, David J. Orlicky, Holly J. Hulsebus, Elizabeth J. Kovacs
    Immunity & Ageing.2021;[Epub]     CrossRef
  • Role of Barrier Integrity and Dysfunctions in Maintaining the Healthy Gut and Their Health Outcomes
    Shruti Panwar, Sapna Sharma, Prabhanshu Tripathi
    Frontiers in Physiology.2021;[Epub]     CrossRef
  • Chlorothalonil induces the intestinal epithelial barrier dysfunction in Caco-2 cell-based <italic>in vitro</italic> monolayer model by activating MAPK pathway
    Huaping Tao, Zhiwei Bao, Zhengwei Fu, Yuanxiang Jin
    Acta Biochimica et Biophysica Sinica.2021; 53(11): 1459.     CrossRef
  • Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model
    Bi-Ying Jin, Zhen Li, Ya-Nan Xia, Li-Xiang Li, Zi-Xiao Zhao, Xiao-Yu Li, Yan Li, Bing Li, Ru-Chen Zhou, Shi-Chen Fu, Shi-Yang Li, Yan-Qing Li
    Frontiers in Immunology.2021;[Epub]     CrossRef
  • Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An in vitro and in vivo Studies
    Shengwei Chen, Yi Zhang, Xueting Niu, Sahar Ghulam Mohyuddin, Jiayin Wen, Minglong Bao, Tianyue Yu, Lianyun Wu, Canyin Hu, Yanhong Yong, Xiaoxi Liu, A. M. Abd El-Aty, Xianghong Ju
    Frontiers in Nutrition.2021;[Epub]     CrossRef
  • Recombinant CRAMP-producing Lactococcus lactis attenuates dextran sulfate sodium-induced colitis by colonic colonization and inhibiting p38/NF-κB signaling
    Jiahong Li, Shiwen Yu, Xiaohua Pan, Ming Zhang, Zhuwu Lv, Li-Long Pan, Jia Sun
    Food & Nutrition Research.2021;[Epub]     CrossRef
  • The combined supplementation of omega-3 fatty acids and probiotics decreased the levels of serum polyamines in experimental colitis
    Havvanur Yoldaş İlktaç, Nihal Büyükuslu, Cüneyd Parlayan
    Food and Health.2021; 7(4): 279.     CrossRef
  • P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency
    Jiawen Zhou, Chenxing Hou, Haiyun Chen, Ziyue Qin, Zi’an Miao, Jingyu Zhao, Qiuyi Wang, Min Cui, Chunfeng Xie, Rong Wang, Qing Li, Guoping Zuo, Dengshun Miao, Jianliang Jin
    Frontiers in Cell and Developmental Biology.2021;[Epub]     CrossRef
  • Curcumin Reduces Adipose Tissue Inflammation and Alters Gut Microbiota in Diet‐Induced Obese Male Mice
    Tariful Islam, Iurii Koboziev, Kembra Albracht‐Schulte, Brandon Mistretta, Shane Scoggin, Mohammad Yosofvand, Hanna Moussa, Masoud Zabet‐Moghaddam, Latha Ramalingam, Preethi H. Gunaratne, Naima Moustaid‐Moussa
    Molecular Nutrition & Food Research.2021;[Epub]     CrossRef
  • Altered Intestinal Permeability and Drug Repositioning in a Post-operative Ileus Guinea Pig Model
    Young Min Kim, Zahid Hussain, Young Ju Lee, Hyojin Park
    Journal of Neurogastroenterology and Motility.2021; 27(4): 639.     CrossRef
  • Pediococcus pentosaceus IM96 Exerts Protective Effects against Enterohemorrhagic Escherichia coli O157:H7 Infection In Vivo
    Haixin Li, Xinqiang Xie, Ying Li, Moutong Chen, Liang Xue, Juan Wang, Jumei Zhang, Shi Wu, Qinghua Ye, Shuhong Zhang, Runshi Yang, Hui Zhao, Lei Wu, Tingting Liang, Yu Ding, Qingping Wu
    Foods.2021; 10(12): 2945.     CrossRef
  • Extracellular Vesicles Derived From Citrus sinensis Modulate Inflammatory Genes and Tight Junctions in a Human Model of Intestinal Epithelium
    Stefania Paola Bruno, Alessandro Paolini, Valentina D'Oria, Angelo Sarra, Simona Sennato, Federico Bordi, Andrea Masotti
    Frontiers in Nutrition.2021;[Epub]     CrossRef
  • The Microbiota and Kidney Transplantation: Influence on the Graft
    Maurizio Salvadori, Aris Tsalouchos
    EMJ Urology.2021; : 95.     CrossRef
  • MicroRNA Expression and Intestinal Permeability in Children Living in a Slum Area of Bangladesh
    Humaira Rashid, Towfida J. Siddiqua, Biplob Hossain, Abdullah Siddique, Mamun Kabir, Zannatun Noor, Masud Alam, Mamun Ahmed, Rashidul Haque
    Frontiers in Molecular Biosciences.2021;[Epub]     CrossRef
  • The Protective Effects of Lactoferrin on Aflatoxin M1-Induced Compromised Intestinal Integrity
    Ya-Nan Gao, Song-Li Li, Xue Yang, Jia-Qi Wang, Nan Zheng
    International Journal of Molecular Sciences.2021; 23(1): 289.     CrossRef
  • Renovation of Intestinal Barrier by Polydatin in Experimentally Induced Ulcerative Colitis: Comparative Ultrastructural Study with L-Carnosine
    Hasnaa Ali Ebrahim, Dalia Mahmoud Abdelmonem Elsherbini
    Cells Tissues Organs.2021; 210(4): 275.     CrossRef
  • Isolation and Characterization of Blueberry Polyphenolic Components and Their Effects on Gut Barrier Dysfunction
    Michael A. Polewski, Daniel Esquivel-Alvarado, Nicholas S. Wedde, Christian G. Kruger, Jess D. Reed
    Journal of Agricultural and Food Chemistry.2020; 68(10): 2940.     CrossRef
  • Polyphenols and Intestinal Permeability: Rationale and Future Perspectives
    Stefano Bernardi, Cristian Del Bo’, Mirko Marino, Giorgio Gargari, Antonio Cherubini, Cristina Andrés-Lacueva, Nicole Hidalgo-Liberona, Gregorio Peron, Raúl González-Dominguez, Paul Kroon, Benjamin Kirkup, Marisa Porrini, Simone Guglielmetti, Patrizia Ris
    Journal of Agricultural and Food Chemistry.2020; 68(7): 1816.     CrossRef
  • Painful interactions: Microbial compounds and visceral pain
    I.A.M. van Thiel, S. Botschuijver, W.J. de Jonge, J. Seppen
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2020; 1866(1): 165534.     CrossRef
  • Autophagy induction by rapamycin ameliorates experimental colitis and improves intestinal epithelial barrier function in IL-10 knockout mice
    Jie Zhao, Honggang Wang, Haojun Yang, Yan Zhou, Liming Tang
    International Immunopharmacology.2020; 81: 105977.     CrossRef
  • Acmella oleracea for pain management
    Mariangela Rondanelli, Federica Fossari, Viviana Vecchio, Valentina Braschi, Antonella Riva, Pietro Allegrini, Giovanna Petrangolini, Giancarlo Iannello, Milena Anna Faliva, Gabriella Peroni, Mara Nichetti, Clara Gasparri, Daniele Spadaccini, Vittoria Inf
    Fitoterapia.2020; 140: 104419.     CrossRef
  • Potential Determinants of Gastrointestinal Dysfunction in Autism Spectrum Disorders
    Anya E. Shindler, Elisa L. Hill-Yardin, Steve Petrovski, Anne C. Cunningham, Naomi Bishop, Ashley E. Franks
    Review Journal of Autism and Developmental Disorders.2020; 7(2): 182.     CrossRef
  • Protective Effect of Naringin on In Vitro Gut-Vascular Barrier Disruption of Intestinal Microvascular Endothelial Cells Induced by TNF-α
    Ping Liu, Yifei Bian, Yingsai Fan, Jia Zhong, Zhongjie Liu
    Journal of Agricultural and Food Chemistry.2020; 68(1): 168.     CrossRef
  • A Review of the Brain-Gut-Microbiome Axis and the Potential Role of Microbiota in Alzheimer’s Disease
    Miao Sun, Kai Ma, Jie Wen, Guangxian Wang, Changliang Zhang, Qi Li, Xiaofeng Bao, Hui Wang
    Journal of Alzheimer's Disease.2020; 73(3): 849.     CrossRef
  • Soybean antigen protein induces caspase-3/mitochondrion-regulated apoptosis in IPEC-J2 cells
    Chenglu Peng, Zhifeng Sun, Lei Wang, Yingshuang Shu, Mengchu He, Hongyan Ding, Yu Li, Xichun Wang, Shibin Feng, Jinchun Li, Jinjie Wu
    Food and Agricultural Immunology.2020; 31(1): 100.     CrossRef
  • Oxidized Pork Induces Oxidative Stress and Inflammation by Altering Gut Microbiota in Mice
    Yueting Ge, Shiman Lin, Bowen Li, Yuhui Yang, Xue Tang, Yonghui Shi, Jin Sun, Guowei Le
    Molecular Nutrition & Food Research.2020;[Epub]     CrossRef
  • Expression of Neurotrophic Factors, Tight Junction Proteins, and Cytokines According to the Irritable Bowel Syndrome Subtype and Sex
    Ju Yup Lee, Nayoung Kim, Ji Hyun Park, Ryoung Hee Nam, Sun Min Lee, Chin-Hee Song, Geun Kim, Hee Young Na, Yoon Jin Choi, Jin Joo Kim, Dong Ho Lee
    Journal of Neurogastroenterology and Motility.2020; 26(1): 106.     CrossRef
  • Effects of Aluminum on the Integrity of the Intestinal Epithelium: An in Vitro and in Vivo Study
    Chang Hee Jeong, Hyuk Cheol Kwon, Do Hyun Kim, Wei Nee Cheng, Sukyung Kang, Dong-Min Shin, Jong Hyeok Yune, Jee Eun Yoon, You Hyun Chang, Hyejin Sohn, Sung Gu Han
    Environmental Health Perspectives.2020;[Epub]     CrossRef
  • Tuna Bone Powder Alleviates Glucocorticoid‐Induced Osteoporosis via Coregulation of the NF‐κB and Wnt/β‐Catenin Signaling Pathways and Modulation of Gut Microbiota Composition and Metabolism
    Jingjing Li, Mingyuan Yang, Chenyang Lu, Jiaojiao Han, Shasha Tang, Jun Zhou, Ye Li, Tinghong Ming, Zaijie Jim Wang, Xiurong Su
    Molecular Nutrition & Food Research.2020;[Epub]     CrossRef
  • Impact of high dietary plant protein with or without marine ingredients in gut mucosa proteome of gilthead seabream (Sparus aurata, L.)
    Guillem Estruch, Silvia Martínez-Llorens, Ana Tomás-Vidal, Raquel Monge-Ortiz, Miguel Jover-Cerdá, Paul B. Brown, David S. Peñaranda
    Journal of Proteomics.2020; 216: 103672.     CrossRef
  • QTL Mapping of Intestinal Neutrophil Variation in Threespine Stickleback Reveals Possible Gene Targets Connecting Intestinal Inflammation and Systemic Health
    Emily A Beck, Mark C Currey, Clayton M Small, William A Cresko
    G3 Genes|Genomes|Genetics.2020; 10(2): 613.     CrossRef
  • Wuchereria bancrofti macrophage migration inhibitory factor‐2 (rWbaMIF‐2) ameliorates experimental colitis
    Shriram Ramani, Nikhil Chauhan, Vishal Khatri, Connie Vitali, Ramaswamy Kalyanasundaram
    Parasite Immunology.2020;[Epub]     CrossRef
  • Aging Increases the Severity of Colitis and the Related Changes to the Gut Barrier and Gut Microbiota in Humans and Mice
    Ailing Liu, Hong Lv, Hongying Wang, Hong Yang, Yue Li, Jiaming Qian, Rozalyn Anderson
    The Journals of Gerontology: Series A.2020; 75(7): 1284.     CrossRef
  • Notch controls urothelial integrity in the mouse bladder
    Varvara Paraskevopoulou, Vangelis Bonis, Vasilis S. Dionellis, Nikolaos Paschalidis, Pelagia Melissa, Evangelia Chavdoula, Eleni Vasilaki, Ioannis S. Pateras, Apostolos Klinakis
    JCI Insight.2020;[Epub]     CrossRef
  • Investigating the gut-brain axis in a neurodevelopmental rodent model of schizophrenia
    Max W. Katz-Barber, Sharon L. Hollins, Annalisa Cuskelly, Angeline J.W. Leong, Ariel Dunn, Lauren Harms, Deborah M. Hodgson
    Brain, Behavior, & Immunity - Health.2020; 3: 100048.     CrossRef
  • Nesfatin-1 ameliorates oxidative bowel injury in rats with necrotizing enterocolitis: The role of the microbiota composition and claudin-3 expression
    Kıvılcım Karadeniz Cerit, Türkan Koyuncuoğlu, Damla Yağmur, İrem Peker Eyüboğlu, Serap Şirvancı, Mustafa Akkiprik, Burak Aksu, E. Tolga Dağlı, Berrak Ç. Yeğen
    Journal of Pediatric Surgery.2020; 55(12): 2797.     CrossRef
  • tRNA Queuosine Modification Enzyme Modulates the Growth and Microbiome Recruitment to Breast Tumors
    Jilei Zhang, Rong Lu, Yongguo Zhang, Żaneta Matuszek, Wen Zhang, Yinglin Xia, Tao Pan, Jun Sun
    Cancers.2020; 12(3): 628.     CrossRef
  • Small silica nanoparticles transiently modulate the intestinal permeability by actin cytoskeleton disruption in both Caco-2 and Caco-2/HT29-MTX models
    Raphaël Cornu, Claire Chrétien, Yann Pellequer, Hélène Martin, Arnaud Béduneau
    Archives of Toxicology.2020; 94(4): 1191.     CrossRef
  • Effect of peritoneal dialysis solution with different pyruvate concentrations on intestinal injury
    Jing-Jing Zhang, Hui-Qin Shen, Jiang-Tao Deng, Lin-Lin Jiang, Qiong-Yue Zhang, Ying Xiong, Zong-Ze Zhang, Yan-Lin Wang
    Experimental Biology and Medicine.2020; 245(7): 644.     CrossRef
  • Vitamin D and intestinal homeostasis: Barrier, microbiota, and immune modulation
    Hana. M.A. Fakhoury, Peter R. Kvietys, Wael AlKattan, Fatme Al Anouti, Muhammad Affan Elahi, Spyridon N. Karras, William B. Grant
    The Journal of Steroid Biochemistry and Molecular Biology.2020; 200: 105663.     CrossRef
  • Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice
    Yuxin Cheng, Ting Wu, Shuxin Tang, Fuqiang Liang, Yajing Fang, Weiwei Cao, Siyi Pan, Xiaoyun Xu
    Food & Function.2020; 11(4): 3167.     CrossRef
  • A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota
    Chunxiao Ren, Yijiang Wang, Xiaofeng Lin, Hanqing Song, Qiqi Zhou, Wan Xu, Kui Shi, Jun Chen, Junshuai Song, Fang Chen, Shihai Zhang, Wutai Guan
    Journal of Agricultural and Food Chemistry.2020; 68(14): 4155.     CrossRef
  • cis9,trans11, but nottrans10,cis12 CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice through activation of GPR120-[Ca2+]iand the MLCK signaling pathway
    Han Su, Weijie Zhao, Fenglin Zhang, Min Song, Fangfang Liu, Jisong Zheng, Mingfa Ling, Xiaohua Yang, Qiang Yang, Haiwen He, Lin Chen, Xumin Lai, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
    Food & Function.2020; 11(4): 3657.     CrossRef
  • Transport, metabolism and remedial potential of functional food extracts (FFEs) in Caco-2 cells monolayer: A review
    Maryam Iftikhar, Asra Iftikhar, Huijuan Zhang, Lingxiao Gong, Jing Wang
    Food Research International.2020; 136: 109240.     CrossRef
  • Nanosphere-shaped ammonio methacrylate copolymers: converting a pharmaceutical inactive ingredient to efficient therapeutics for experimental colitis
    Brice Moulari, Maryam A. Shetab Boushehri, Jean-Paul Pais de Barros, Thilo Faber, Arnaud Béduneau, Laurent Lagrost, Yann Pellequer, Alf Lamprecht
    Nanoscale.2020; 12(17): 9590.     CrossRef
  • Lycium barbarum polysaccharides ameliorate intestinal barrier dysfunction and inflammation through the MLCK-MLC signaling pathway in Caco-2 cells
    Wei Li, Mingbo Gao, Ting Han
    Food & Function.2020; 11(4): 3741.     CrossRef
  • Knockdown of ghrelin‐O‐acyltransferase attenuates colitis through the modulation of inflammatory factors and tight junction proteins in the intestinal epithelium
    Peiying Tian, Xiaolan Lu, Nuyun Jin, Jianping Shi
    Cell Biology International.2020; 44(8): 1681.     CrossRef
  • Dynamics of Intestinal Inflammatory Cytokines and Tight Junction Proteins of Turbot (Scophthalmus maximus L.) During the Development and Recovery of Enteritis Induced by Dietary β-Conglycinin
    Jing Zheng, Pei Yang, Jihong Dai, Guijuan Yu, Weihao Ou, Weiqi Xu, Kangsen Mai, Yanjiao Zhang
    Frontiers in Marine Science.2020;[Epub]     CrossRef
  • Expression of Tight Junction Proteins According to Functional Dyspepsia Subtype and Sex
    Ju Yup Lee, Nayoung Kim, Yoon Jin Choi, Ji Hyun Park, Hassan Ashktorab, Duane T Smoot, Dong Ho Lee
    Journal of Neurogastroenterology and Motility.2020; 26(2): 248.     CrossRef
  • Maternal dietary uridine supplementation reduces diarrhea incidence in piglets by regulating the intestinal mucosal barrier and cytokine profiles
    Xin Wu, Lu‐Min Gao, Yi‐Lin Liu, Chunyan Xie, Lichuang Cai, Kang Xu, Xi‐Hong Zhou
    Journal of the Science of Food and Agriculture.2020; 100(9): 3709.     CrossRef
  • Microphysiological Engineering of Immune Responses in Intestinal Inflammation
    Yoko M. Ambrosini, Woojung Shin, Soyoun Min, Hyun Jung Kim
    Immune Network.2020;[Epub]     CrossRef
  • Dietary supplementation of l-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction
    Hao Zhang, Yi Ma, Mengzhi Wang, Mabrouk Elsabagh, Juan J. Loor, Hongrong Wang
    Food & Function.2020; 11(5): 4456.     CrossRef
  • Particulate Matter Decreases Intestinal Barrier-Associated Proteins Levels in 3D Human Intestinal Model
    Brittany Woodby, Maria Lucia Schiavone, Erika Pambianchi, Angela Mastaloudis, Shelly N. Hester, Steven M. Wood, Alessandra Pecorelli, Giuseppe Valacchi
    International Journal of Environmental Research and Public Health.2020; 17(9): 3234.     CrossRef
  • Tri-n-butyl phosphate induced earthworm intestinal damage by influencing nutrient absorption and energy homeostasis of intestinal epithelial cells
    Yang Yang, Peng Liu, Mei Li
    Journal of Hazardous Materials.2020; 398: 122850.     CrossRef
  • Inhibitory Effects of Carrageenans on Endotoxin-Induced Inflammation
    Irina M. Yermak, Aleksandra V. Volod’ko, Eleonora I. Khasina, Viktoriya N. Davydova, Evgeniy A. Chusovitin, Dmitry L. Goroshko, Anna O. Kravchenko, Tamara F. Solov’eva, Victor V. Maleev
    Marine Drugs.2020; 18(5): 248.     CrossRef
  • Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets
    Hao Zhang, Yanan Chen, Yueping Chen, Shuli Ji, Peilu Jia, Yue Li, Tian Wang
    Journal of Animal Science and Biotechnology.2020;[Epub]     CrossRef
  • Mucus blocks probiotics but increases penetration of motile pathogens and induces TNF‐α and IL‐8 secretion
    Abhinav Sharma, Vishnu Raman, Jungwoo Lee, Neil S. Forbes
    Biotechnology and Bioengineering.2020; 117(8): 2540.     CrossRef
  • Ameliorative effects of L-theanine on dextran sulfate sodium induced colitis in C57BL/6J mice are associated with the inhibition of inflammatory responses and attenuation of intestinal barrier disruption
    Dongxu Wang, Min Cai, Taotao Wang, Tiantian Liu, Jinbao Huang, Yijun Wang, Daniel Granato
    Food Research International.2020; 137: 109409.     CrossRef
  • The ameliorative effect of Lactobacillus plantarum Y44 oral administration on inflammation and lipid metabolism in obese mice fed with a high fat diet
    Yujun Liu, Yuan Gao, Fenglian Ma, Mengying Sun, Guangqing Mu, Yanfeng Tuo
    Food & Function.2020; 11(6): 5024.     CrossRef
  • Cyanobacterial lipopeptides puwainaphycins and minutissamides induce disruptive and pro-inflammatory processes in Caco-2 human intestinal barrier model
    Ondřej Vašíček, Jan Hájek, Lucie Bláhová, Pavel Hrouzek, Pavel Babica, Lukáš Kubala, Lenka Šindlerová
    Harmful Algae.2020; 96: 101849.     CrossRef
  • Dietary fermented soybean meal inclusion improves growth performance and ileal barrier function of the weaned piglets challenged by enterotoxigenic Escherichia coli K88
    Yuan Wang, Wenwen Wang, Ruifang Wang, Xiran Hao, Yuanxiao Duan, Ziqi Meng, Xiaoping An, Jingwei Qi
    Animal Feed Science and Technology.2020; 268: 114596.     CrossRef
  • Regulatory Effect of Lactobacillus brevis Bmb6 on Gut Barrier Functions in Experimental Colitis
    Mi-Young Shin, Cheng-Chung Yong, Sejong Oh
    Foods.2020; 9(7): 864.     CrossRef
  • Interactive effect of dietary calcium and phytase on broilers challenged with subclinical necrotic enteritis: part 2. Gut permeability, phytate ester concentrations, jejunal gene expression, and intestinal morphology
    H.K. Zanu, S.K. Kheravii, N.K. Morgan, M.R. Bedford, R.A. Swick
    Poultry Science.2020; 99(10): 4914.     CrossRef
  • The intestinal microbiota in psoriasis
    Monika Koper, Anna Woźniacka, Ewa Robak
    Postępy Higieny i Medycyny Doświadczalnej.2020; 74: 236.     CrossRef
  • Effects of the polysaccharide SPS-3-1 purified from Spirulina on barrier integrity and proliferation of Caco-2 cells
    Qun Wang, Fei Liu, Xuexiang Chen, Zhijie Yang, Yong Cao
    International Journal of Biological Macromolecules.2020; 163: 279.     CrossRef
  • Commercial whey products promote intestinal barrier function with glycomacropeptide enhanced activity in downregulating bacterial endotoxin lipopolysaccharides (LPS)-induced inflammation in vitro
    Shirley Arbizu, Boon Chew, Susanne U. Mertens-Talcott, Giuliana Noratto
    Food & Function.2020; 11(7): 5842.     CrossRef
  • Intestinal Inflammation Induced by Soybean Meal Ingestion Increases Intestinal Permeability and Neutrophil Turnover Independently of Microbiota in Zebrafish
    Camila J. Solis, M. Kristina Hamilton, Mario Caruffo, Juan P. Garcia-Lopez, Paola Navarrete, Karen Guillemin, Carmen G. Feijoo
    Frontiers in Immunology.2020;[Epub]     CrossRef
  • Pulmonary arterial hypertension-associated changes in gut pathology and microbiota
    Ravindra K. Sharma, Aline C. Oliveira, Tao Yang, Seungbum Kim, Jasenka Zubcevic, Victor Aquino, Gilberto O. Lobaton, Ruby Goel, Elaine M. Richards, Mohan K. Raizada
    ERJ Open Research.2020; 6(3): 00253-2019.     CrossRef
  • Anti-Inflammatory Properties of Mineral-Balanced Deep Sea Water in In-Vitro and In-Vivo Models of Inflamed Intestinal Epithelium
    Jain Nam, Kyeong Jin Kim, Geonhee Park, Byeong Goo Kim, Gwi-Hwa Jeong, Jong-eun Jeon, Byung Serk Hurh, Ji Yeon Kim
    Applied Sciences.2020; 10(15): 5183.     CrossRef
  • Barrier Protection and Recovery Effects of Gut Commensal Bacteria on Differentiated Intestinal Epithelial Cells In Vitro
    Nooshin Mohebali, Katharina Ekat, Bernd Kreikemeyer, Anne Breitrück
    Nutrients.2020; 12(8): 2251.     CrossRef
  • Changes in intestinal barrier functions and gut microbiota in rats exposed to zearalenone
    Wei Zhang, Shihua Zhang, Jingjing Wang, Anshan Shan, Li Xu
    Ecotoxicology and Environmental Safety.2020; 204: 111072.     CrossRef
  • Acute Diarrhea in Dogs: Current Management and Potential Role of Dietary Polyphenols Supplementation
    Alessia Candellone, Matteo Cerquetella, Flavia Girolami, Paola Badino, Rosangela Odore
    Antioxidants.2020; 9(8): 725.     CrossRef
  • Bacteria Remediate the Effects of Food Additives on Intestinal Function in an in vitro Model of the Gastrointestinal Tract
    Mridu Malik, Sanjeena Subedi, Cláudia N. H. Marques, Gretchen J. Mahler
    Frontiers in Nutrition.2020;[Epub]     CrossRef
  • Zonula occludens and nasal epithelial barrier integrity in allergic rhinitis
    Che Othman Siti Sarah, Norasnieda Md Shukri, Noor Suryani Mohd Ashari, Kah Keng Wong
    PeerJ.2020; 8: e9834.     CrossRef
  • Maintaining intestinal structural integrity is a potential protective mechanism against inflammation in goose fatty liver
    Wang Gu, Kang Wen, Chunchi Yan, Shuo Li, Tongjun Liu, Cheng Xu, Long Liu, Minmeng Zhao, Jun Zhang, Tuoyu Geng, Daoqing Gong
    Poultry Science.2020; 99(11): 5297.     CrossRef
  • PARK7 Diminishes Oxidative Stress-Induced Mucosal Damage in Celiac Disease
    Apor Veres-Székely, Mária Bernáth, Domonkos Pap, Réka Rokonay, Beáta Szebeni, István M. Takács, Rita Lippai, Áron Cseh, Attila J. Szabó, Ádám Vannay
    Oxidative Medicine and Cellular Longevity.2020; 2020: 1.     CrossRef
  • Intestinal epithelium integrity after delayed onset of nutrition in broiler chickens
    M.S. Hollemans, J. van Baal, G. de Vries Reilingh, B. Kemp, A. Lammers, S. de Vries
    Poultry Science.2020; 99(12): 6818.     CrossRef
  • Dietary Supplementation with Spray-Dried Porcine Plasma Attenuates Colon Inflammation in a Genetic Mouse Model of Inflammatory Bowel Disease
    Lluïsa Miró, Concepció Amat, Cristina Rosell-Cardona, Joy M. Campbell, Javier Polo, Anna Pérez-Bosque, Miquel Moretó
    International Journal of Molecular Sciences.2020; 21(18): 6760.     CrossRef
  • Development of an Improved 3D in vitro Intestinal Model to Perform Permeability Studies of Paracellular Compounds
    Maria Helena Macedo, Elena Martínez, Cristina C. Barrias, Bruno Sarmento
    Frontiers in Bioengineering and Biotechnology.2020;[Epub]     CrossRef
  • Protective Effect of Glycomacropeptide on Food Allergy with Gastrointestinal Manifestations in a Rat Model through Down-Regulation of Type 2 Immune Response
    Diana Reyes-Pavón, Daniel Cervantes-García, Luis G. Bermúdez-Humarán, Laura Elena Córdova-Dávalos, Andrés Quintanar-Stephano, Mariela Jiménez, Eva Salinas
    Nutrients.2020; 12(10): 2942.     CrossRef
  • Expression profile of lncRNAs and mRNAs in intestinal macrophages
    Qais Naseer, Lulu Liu, Xiaofei Xue, Siche Chen, Jixiang Chen, Jianguo Qu, Lei Cui, Xiaogang Wang, Shengchun Dang
    Molecular Medicine Reports.2020;[Epub]     CrossRef
  • Noninvasive Biomarkers of Gut Barrier Function in Patients Suffering from Diarrhea Predominant-IBS: An Update
    Michele Linsalata, Giuseppe Riezzo, Caterina Clemente, Benedetta D’Attoma, Francesco Russo, Roberta Rizzo
    Disease Markers.2020; 2020: 1.     CrossRef
  • Docosahexaenoic acid alleviates cell injury and improves barrier function by suppressing necroptosis signalling in TNF-α-challenged porcine intestinal epithelial cells
    Kan Xiao, Qiao Xu, Congcong Liu, Pengwei He, Qin Qin, Huiling Zhu, Jing Zhang, Ashley Gin, Guolong Zhang, Yulan Liu
    Innate Immunity.2020; 26(8): 653.     CrossRef
  • In Vitro Antioxidant, Anti-inflammatory, and In Vivo Anticolitis Effects of Combretin A and Combretin B on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice
    Mbiantcha Marius, Dawe Amadou, Atsamo Albert Donatien, Ateufack Gilbert, Yousseu Nana William, Khalid Rauf, Mehreen Arif, Fanta Yadang Sabine Adeline, Njoku Isaac Saint, Hamza Dar, Naeem Ur Rehman, Izhar Ahmad, Paolo Gionchetti
    Gastroenterology Research and Practice.2020; 2020: 1.     CrossRef
  • Mucin-2 knockout is a model of intercellular junction defects, mitochondrial damage and ATP depletion in the intestinal epithelium
    Mariya A. Borisova, Kseniya M. Achasova, Ksenia N. Morozova, Evgeniya N. Andreyeva, Ekaterina A. Litvinova, Anna A. Ogienko, Maryana V. Morozova, Mariya B. Berkaeva, Elena Kiseleva, Elena N. Kozhevnikova
    Scientific Reports.2020;[Epub]     CrossRef
  • Severe acute respiratory syndrome coronavirus‐2 infection and the gut–liver axis
    Sundhar Mohandas, Balasubramaniyan Vairappan
    Journal of Digestive Diseases.2020; 21(12): 687.     CrossRef
  • Significance of vagus nerve function in terms of pathogenesis of psychosocial disorders
    Yoshihiko Kakinuma
    Neurochemistry International.2020; : 104934.     CrossRef
  • A method for rapid generation of model intestinal barriers in vitro
    SV Nikulin, AA Poloznikov, DA Sakharov
    Bulletin of Russian State Medical University.2020;[Epub]     CrossRef
  • A combined microphysiological-computational omics approach in dietary protein evaluation
    Paulus G. M. Jochems, Willem R. Keusters, Antoine H. P. America, Pascale C. S. Rietveld, Shanna Bastiaan-Net, Renata M. C. Ariëns, Monic M. M. Tomassen, Fraser Lewis, Yang Li, Koen G. C. Westphal, Johan Garssen, Harry J. Wichers, Jeroen van Bergenhenegouw
    npj Science of Food.2020;[Epub]     CrossRef
  • Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson’s Disease
    Tennekoon B. Karunaratne, Chijioke Okereke, Marissa Seamon, Sharad Purohit, Chandramohan Wakade, Amol Sharma
    Nutrients.2020; 13(1): 28.     CrossRef
  • Gut-Induced Inflammation during Development May Compromise the Blood-Brain Barrier and Predispose to Autism Spectrum Disorder
    Rebecca S. Eshraghi, Camron Davies, Rahul Iyengar, Linda Perez, Rahul Mittal, Adrien A. Eshraghi
    Journal of Clinical Medicine.2020; 10(1): 27.     CrossRef
  • Modulation of gastrointestinal barrier and nutrient transport function in farm animals by natural plant bioactive compounds – A comprehensive review
    Amlan Kumar Patra, Salah Amasheh, Jörg Rudolf Aschenbach
    Critical Reviews in Food Science and Nutrition.2019; 59(20): 3237.     CrossRef
  • Pharmacological Evaluation of TAK-828F, a Novel Orally Available RORγt Inverse Agonist, on Murine Colitis Model
    Keiko Igaki, Yoshiki Nakamura, Yusaku Komoike, Keiko Uga, Akira Shibata, Yoshimasa Ishimura, Masashi Yamasaki, Yasuhiro Tsukimi, Noboru Tsuchimori
    Inflammation.2019; 42(1): 91.     CrossRef
  • Osteopontin Protects Colonic Mucosa from Dextran Sodium Sulfate-Induced Acute Colitis in Mice by Regulating Junctional Distribution of Occludin
    Sang-Ho Woo, Su-Hyung Lee, Jun-Won Park, Du-Min Go, Dae-Yong Kim
    Digestive Diseases and Sciences.2019; 64(2): 421.     CrossRef
  • An insight into gut microbiota and its functionalities
    Atanu Adak, Mojibur R. Khan
    Cellular and Molecular Life Sciences.2019; 76(3): 473.     CrossRef
  • MicroRNAs and signaling networks involved in epithelial–mesenchymal transition
    Mohammad Hossein Musavi Shenas, Shadi Eghbal‐Fard, Vahid Mehrisofiani, Nima Abd Yazdani, Omid Rahbar Farzam, Faroogh Marofi, Mehdi Yousefi
    Journal of Cellular Physiology.2019; 234(5): 5775.     CrossRef
  • Purification and identification of intestinal mucosal cell proliferation-promoting peptides from Crassostrea hongkongensis
    Jianyu Pan, Peng Wan, Deke Chen, Hua Chen, Xin Chen, Huili Sun, Bingna Cai
    European Food Research and Technology.2019; 245(3): 631.     CrossRef
  • The possible role of bacteria, viruses, and parasites in initiation and exacerbation of irritable bowel syndrome
    Aref Shariati, Fateme Fallah, Ali Pormohammad, Ali Taghipour, Hossein Safari, Alireza salami chirani, Sahar Sabour, Mahmood Alizadeh‐Sani, Taher Azimi
    Journal of Cellular Physiology.2019; 234(6): 8550.     CrossRef
  • Acute effects of milk polar lipids on intestinal tight junction expression: towards an impact of sphingomyelin through the regulation of IL-8 secretion?
    Marine Milard, Armelle Penhoat, Annie Durand, Charline Buisson, Emmanuelle Loizon, Emmanuelle Meugnier, Karène Bertrand, Florent Joffre, David Cheillan, Lorna Garnier, Sébastien Viel, Fabienne Laugerette, Marie-Caroline Michalski
    The Journal of Nutritional Biochemistry.2019; 65: 128.     CrossRef
  • Resveratrol improves intestinal barrier function, alleviates mitochondrial dysfunction and induces mitophagy in diquat challenged piglets1
    Shuting Cao, Zhuojun Shen, Chunchun Wang, Qianhui Zhang, Qihua Hong, Yonghui He, Caihong Hu
    Food & Function.2019; 10(1): 344.     CrossRef
  • The In Vitro Protective Role of Bovine Lactoferrin on Intestinal Epithelial Barrier
    Xiao Zhao, Xiao-Xi Xu, Yang Liu, En-Ze Xi, Jing-Jing An, Dina Tabys, Ning Liu
    Molecules.2019; 24(1): 148.     CrossRef
  • Effect of caseinate glycation with oligochitosan and transglutaminase on the intestinal barrier function of the tryptic caseinate digest in IEC-6 cells
    Jia Shi, Xin-Huai Zhao
    Food & Function.2019; 10(2): 652.     CrossRef
  • A Role of Exopolysaccharide Produced by Streptococcus thermophilus in the Intestinal Inflammation and Mucosal Barrier in Caco-2 Monolayer and Dextran Sulphate Sodium-Induced Experimental Murine Colitis
    Yun Chen, Ming Zhang, Fazheng Ren
    Molecules.2019; 24(3): 513.     CrossRef
  • Red wine extract preserves tight junctions in intestinal epithelial cells under inflammatory conditions: implications for intestinal inflammation
    Carla Nunes, Víctor Freitas, Leonor Almeida, João Laranjinha
    Food & Function.2019; 10(3): 1364.     CrossRef
  • Long-term in vitro 3D hydrogel co-culture model of inflammatory bowel disease
    Rasha H. Dosh, Nicola Jordan-Mahy, Christopher Sammon, Christine L. Le Maitre
    Scientific Reports.2019;[Epub]     CrossRef
  • Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?
    Gerwyn Morris, Michael Maes, Michael Berk, Basant K. Puri
    Metabolic Brain Disease.2019; 34(2): 385.     CrossRef
  • Collagen peptides administration in early enteral nutrition intervention attenuates burn-induced intestinal barrier disruption: Effects on tight junction structure
    Qianru Chen, Xiang Gao, Hongwei Zhang, Bafang Li, Guangli Yu, Bo Li
    Journal of Functional Foods.2019; 55: 167.     CrossRef
  • Protein Phosphatase 2A: More Than a Passenger in the Regulation of Epithelial Cell–Cell Junctions
    Diana Schuhmacher, Jean-Marie Sontag, Estelle Sontag
    Frontiers in Cell and Developmental Biology.2019;[Epub]     CrossRef
  • The Influence of Heat-Killed Enterococcus faecium BGPAS1-3 on the Tight Junction Protein Expression and Immune Function in Differentiated Caco-2 Cells Infected With Listeria monocytogenes ATCC 19111
    Nikola Popović, Jelena Djokić, Emilija Brdarić, Miroslav Dinić, Amarela Terzić-Vidojević, Nataša Golić, Katarina Veljović
    Frontiers in Microbiology.2019;[Epub]     CrossRef
  • Inonotus obliquus polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance
    Yi-Fang Chen, Jin-Juan Zheng, Chao Qu, Yao Xiao, Fang-Fang Li, Quan-Xin Jin, Hong-Hua Li, Fan-Ping Meng, Gui-Hua Jin, Dan Jin
    Artificial Cells, Nanomedicine, and Biotechnology.2019; 47(1): 757.     CrossRef
  • N-(1-carbamoyl-2-phenylethyl) butyramide reduces antibiotic-induced intestinal injury, innate immune activation and modulates microbiota composition
    Adriano Lama, Chiara Annunziata, Lorena Coretti, Claudio Pirozzi, Francesca Di Guida, Allegra Nitrato Izzo, Claudia Cristiano, Maria Pina Mollica, Lorenzo Chiariotti, Alessandra Pelagalli, Francesca Lembo, Rosaria Meli, Giuseppina Mattace Raso
    Scientific Reports.2019;[Epub]     CrossRef
  • Influence of the Maillard-type caseinate glycation with lactose on the intestinal barrier activity of the caseinate digest in IEC-6 cells
    Jia Shi, Xin-Huai Zhao
    Food & Function.2019; 10(4): 2010.     CrossRef
  • Anti-inflammatory effect of Lycium barbarum on polarized human intestinal epithelial cells
    So-Rok Lee, Hye-Jeong Hwang, Ju-Gyeong Yoon, Eun Young Bae, Kyo-Suk Goo, Sang-Joon Cho, Jin Ah Cho
    Nutrition Research and Practice.2019; 13(2): 95.     CrossRef
  • Unexplained inflammation in end‐stage kidney disease: Is the combination of enhanced gastrointestinal permeability and reticuloendothelial dysfunction its cause?
    Oscar Swift, Enric Vilar, Ken Farrington
    Seminars in Dialysis.2019; 32(5): 417.     CrossRef
  • Lactoferrin in Aseptic and Septic Inflammation
    Maria Stefania Lepanto, Luigi Rosa, Rosalba Paesano, Piera Valenti, Antimo Cutone
    Molecules.2019; 24(7): 1323.     CrossRef
  • Mechanisms by Which the Gut Microbiota Influences Cytokine Production and Modulates Host Inflammatory Responses
    Viviani Mendes, Izabela Galvão, Angelica Thomaz Vieira
    Journal of Interferon & Cytokine Research.2019; 39(7): 393.     CrossRef
  • High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers
    Wajiha Gohir, Katherine M. Kennedy, Jessica G. Wallace, Michelle Saoi, Christian J. Bellissimo, Philip Britz‐McKibbin, Jim J. Petrik, Michael G. Surette, Deborah M. Sloboda
    The Journal of Physiology.2019; 597(12): 3029.     CrossRef
  • Dietary probiotic form modulates broiler gut microbiota indices and expression of gut barrier genes including essential components for gut homeostasis
    Konstantinos C. Mountzouris, Irida Palamidi, Vasileios Paraskeuas, Eirini Griela, Konstantinos Fegeros
    Journal of Animal Physiology and Animal Nutrition.2019; 103(4): 1143.     CrossRef
  • Bacillus licheniformis Zhengchangsheng® attenuates DSS-induced colitis and modulates the gut microbiota in mice
    Y. Li, M. Liu, J. Zhou, B. Hou, X. Su, Z. Liu, J. Yuan, M. Li
    Beneficial Microbes.2019; 10(5): 543.     CrossRef
  • A Fixed Combination of Probiotics and Herbal Extracts Attenuates Intestinal Barrier Dysfunction from Inflammatory Stress in an In vitro Model Using Caco-2 Cells
    Veronica Cocetta, Daniela Catanzaro, Vittoria Borgonetti, Eugenio Ragazzi, Maria C. Giron, Paolo Governa, Ilaria Carnevali, Marco Biagi, Monica Montopoli
    Recent Patents on Food, Nutrition & Agriculture.2019; 10(1): 62.     CrossRef
  • The administration of Escherichia coli Nissle 1917 ameliorates irinotecan–induced intestinal barrier dysfunction and gut microbial dysbiosis in mice
    Yurong Wang, Lie Sun, Shanwen Chen, Shihao Guo, Taohua Yue, Qisheng Hou, Mei Feng, Hao Xu, Yucun Liu, Pengyuan Wang, Yisheng Pan
    Life Sciences.2019; 231: 116529.     CrossRef
  • Surface-layer protein from Lactobacillus acidophilus NCFM attenuates tumor necrosis factor-α-induced intestinal barrier dysfunction and inflammation
    Huifang Wang, Qiuxiang Zhang, Yuhan Niu, Xin Zhang, Rongrong Lu
    International Journal of Biological Macromolecules.2019; 136: 27.     CrossRef
  • Extracellular vesicles and soluble factors secreted by Escherichia coli Nissle 1917 and ECOR63 protect against enteropathogenic E. coli-induced intestinal epithelial barrier dysfunction
    Carina-Shianya Alvarez, Rosa Giménez, María-Alexandra Cañas, Rodrigo Vera, Natalia Díaz-Garrido, Josefa Badia, Laura Baldomà
    BMC Microbiology.2019;[Epub]     CrossRef
  • Pretreatment with probiotic Enterococcus faecium NCIMB 11181 ameliorates necrotic enteritis-induced intestinal barrier injury in broiler chickens
    Yuanyuan Wu, Wenrui Zhen, Yanqiang Geng, Zhong Wang, Yuming Guo
    Scientific Reports.2019;[Epub]     CrossRef
  • β-Conglycinin-Induced Intestinal Porcine Epithelial Cell Damage via the Nuclear Factor κB/Mitogen-Activated Protein Kinase Signaling Pathway
    Chenglu Peng, Xuedong Ding, Lei Zhu, Mengchu He, Yingshuang Shu, Yu Zhang, Yu Li, Xichun Wang, Shibin Feng, Jinchun Li, Jinjie Wu
    Journal of Agricultural and Food Chemistry.2019; 67(32): 9009.     CrossRef
  • Occludin endocytosis is involved in the disruption of the intestinal epithelial barrier in a mouse model of alcoholic steatohepatitis
    Hong Yan Wang, Cheng Chi, You Qing Xu, Chen Wang, Tian Yi Wang, Dong Lv, Xin Li
    Journal of Digestive Diseases.2019; 20(9): 476.     CrossRef
  • Biomaterial–tight junction interaction and potential impacts
    Xiangfei Han, Ershuai Zhang, Yuanjie Shi, Boyi Song, Hong Du, Zhiqiang Cao
    Journal of Materials Chemistry B.2019; 7(41): 6310.     CrossRef
  • Original low birth weight deteriorates the hindgut epithelial barrier function in pigs at the growing stage
    Shiyu Tao, Yu Bai, Tiantian Li, Na Li, Junjun Wang
    The FASEB Journal.2019; 33(9): 9897.     CrossRef
  • Activation of epithelial cells by the major kiwifruit allergen Act d 1 in human and mouse-derived intestinal model
    Andrijana Nešić, Annemarie Stam, Milena Čavić, Jean Paul Ten Klooster, Raymond Pieters, Joost Smit, Marija Gavrović-Jankulović
    Journal of Functional Foods.2019; 62: 103556.     CrossRef
  • Myalgic encephalomyelitis/chronic fatigue syndrome: From pathophysiological insights to novel therapeutic opportunities
    Gerwyn Morris, Basant K. Puri, Adam J. Walker, Michael Maes, Andre F. Carvalho, Ken Walder, Catherine Mazza, Michael Berk
    Pharmacological Research.2019; 148: 104450.     CrossRef
  • Cinobufacini ameliorates experimental colitis via modulating the composition of gut microbiota
    Yongfeng Bai, Siwei Wang, Wenkai Xu, Yuanyuan Weng, Shengmei Zhu, Hao Sheng, Jin Zhu, Feng Zhang, François Blachier
    PLOS ONE.2019; 14(9): e0223231.     CrossRef
  • Chronic Stress, Inflammation, and Colon Cancer: A CRH System-Driven Molecular Crosstalk
    Stavroula Baritaki, Eelco de Bree, Ekaterini Chatzaki, Charalabos Pothoulakis
    Journal of Clinical Medicine.2019; 8(10): 1669.     CrossRef
  • Intestinal anti-inflammatory activity of xique–xique (Pilosocereus gounelleiA. Weber ex K. Schum. Bly. Ex Rowl) juice on acetic acid-induced colitis in rats
    Paloma Oliveira Antonino de Assis, Gerlane Coelho Bernardo Guerra, Daline Fernandes de Souza Araújo, Leylliane de Fátima Leal Interaminense de Andrade, Aurigena Antunes de Araújo, Raimundo Fernandes de Araújo, Thaís Gomes de Carvalho, Maria de Fátima Vand
    Food & Function.2019; 10(11): 7275.     CrossRef
  • AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells
    Séverine Olivier, Jocelyne Leclerc, Adrien Grenier, Marc Foretz, Jérôme Tamburini, Benoit Viollet
    International Journal of Molecular Sciences.2019; 20(20): 5171.     CrossRef
  • Risk factors for peritonitis in patients on continuous ambulatory peritoneal dialysis who undergo colonoscopy: a retrospective multicentre study
    Tae-Geun Gweon, Sung Hoon Jung, Sang Woo Kim, Kang-Moon Lee, Dae Young Cheung, Bo-In Lee, Hwang Choi
    BMC Gastroenterology.2019;[Epub]     CrossRef
  • Effects of dietary fiber sources during late gestation and lactation on sow performance, milk quality, and intestinal health in piglets1
    Qinghui Shang, Hansuo Liu, Sujie Liu, Tengfei He, Xiangshu Piao
    Journal of Animal Science.2019; 97(12): 4922.     CrossRef
  • Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function
    Ziwen Yuan, Lihong Yang, Xiaosong Zhang, Peng Ji, Yongli Hua, Yanming Wei
    Frontiers in Pharmacology.2019;[Epub]     CrossRef
  • Endotoxemia And Intestinal Barrier Disorders Associated With Overweight And Obesity
    Agata Janczy, Zdzisław Kochan, Sylwia Małgorzewicz
    Postępy Mikrobiologii - Advancements of Microbiology.2019; 58(4): 427.     CrossRef
  • Tight joints and zonulin in the formation of oral tolerance and food allergy
    N. G. Prikhodchenko, T. A. Shumatova, L. A. Grigoryan, A. V. Gordeets
    Pacific Medical Journal.2019; (4): 5.     CrossRef
  • Anthocyanins and intestinal barrier function: a review
    Jonathan C. Valdez, Bradley W. Bolling
    Journal of Food Bioactives.2019; : 18.     CrossRef
  • The role of polymorphonuclear neutrophils during HIV-1 infection
    Mahmoud Mohammad Yaseen, Nizar Mohammad Abuharfeil, Mohammad Mahmoud Yaseen, Barakat Mohammad Shabsoug
    Archives of Virology.2018; 163(1): 1.     CrossRef
  • Allyl Isothiocyanate Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mouse by Enhancing Tight Junction and Mucin Expression
    Min Woo Kim, Seungho Choi, Sun Yeou Kim, Yeo Sung Yoon, Ju-Hee Kang, Seung Hyun Oh
    International Journal of Molecular Sciences.2018; 19(7): 2025.     CrossRef
  • Retinoic Acid, Leaky Gut, and Autoimmune Diseases
    Leila Abdelhamid, Xin Luo
    Nutrients.2018; 10(8): 1016.     CrossRef
  • The multiple faces of inflammatory enteric glial cells: is Crohn’s disease a gliopathy?
    Camille Pochard, Sabrina Coquenlorge, Marie Freyssinet, Philippe Naveilhan, Arnaud Bourreille, Michel Neunlist, Malvyne Rolli-Derkinderen
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2018; 315(1): G1.     CrossRef
  • Lignosulfonic acid attenuates NF-κB activation and intestinal epithelial barrier dysfunction induced by TNF-α/IFN-γ in Caco-2 cells
    Koji Matsuhisa, Akihiro Watari, Kazuki Iwamoto, Masuo Kondoh, Kiyohito Yagi
    Journal of Natural Medicines.2018; 72(2): 448.     CrossRef
  • Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function
    Zhiqiang Li, Inamul Kabir, Gladys Tietelman, Chongmin Huan, Jianglin Fan, Tilla Worgall, Xian-Cheng Jiang
    Cell Death & Disease.2018;[Epub]     CrossRef
  • The role of the gut microbiota in the pathology and prevention of liver disease
    Alejandra Altamirano-Barrera, Misael Uribe, Norberto C. Chávez-Tapia, Natalia Nuño-Lámbarri
    The Journal of Nutritional Biochemistry.2018; 60: 1.     CrossRef
  • Rhamnogalacturonan, a chemically-defined polysaccharide, improves intestinal barrier function in DSS-induced colitis in mice and human Caco-2 cells
    Daniele Maria-Ferreira, Adamara Machado Nascimento, Thales Ricardo Cipriani, Arquimedes Paixão Santana-Filho, Paulo da Silva Watanabe, Debora de Mello Gonçales Sant´Ana, Fernando Bittencourt Luciano, Karla Carolina Paiva Bocate, René M. van den Wijngaard,
    Scientific Reports.2018;[Epub]     CrossRef
  • Effect of Oxidized Soybean Oils on Oxidative Status and Intestinal Barrier Function in Broiler Chickens
    L Tan, D Rong, Y Yang, B Zhang
    Brazilian Journal of Poultry Science.2018; 20(2): 333.     CrossRef
  • Lactobacillus reuteristrains protect epithelial barrier integrity of IPEC-J2 monolayers from the detrimental effect of enterotoxigenicEscherichia coli
    Shokoufeh Karimi, Hans Jonsson, Torbjörn Lundh, Stefan Roos
    Physiological Reports.2018; 6(2): e13514.     CrossRef
  • Direct peritoneal resuscitation reduces intestinal permeability after brain death
    Jessica L. Weaver, Paul J. Matheson, Amy Matheson, Victoria Graham, Brian G. Harbrecht, Cynthia D. Downard, R. Neal Garrison, Jason W. Smith
    Journal of Trauma and Acute Care Surgery.2018; 84(2): 265.     CrossRef
  • Effects of lactobacilli with different regulatory behaviours on tight junctions in mice with dextran sodium sulphate-induced colitis
    Gang Wang, Qi Xu, Xing Jin, Feng Hang, Zhenmin Liu, Jianxin Zhao, Hao Zhang, Wei Chen
    Journal of Functional Foods.2018; 47: 107.     CrossRef
  • ERK1/2-mediated autophagy is essential for cell survival under Ochratoxin A exposure in IPEC-J2 cells
    Hong Wang, Hu Li, Xingxiang Chen, Kehe Huang
    Toxicology and Applied Pharmacology.2018; 360: 38.     CrossRef
  • Temperature-treated gluten proteins in Gluten-Friendly™ bread increase mucus production and gut-barrier function in human intestinal goblet cells
    Carmela Lamacchia, Daniela Musaico, Mary E. Henderson, Triana Bergillos-Meca, Morgane Roul, Loretta Landriscina, Ivana Decina, Giulia Corona, Adele Costabile
    Journal of Functional Foods.2018; 48: 507.     CrossRef
  • Oregonin inhibits inflammation and protects against barrier disruption in intestinal epithelial cells
    Jin-Hua Chi, Geom Seog Seo, Sung Hee Lee
    International Immunopharmacology.2018; 59: 134.     CrossRef
  • The biological challenges and pharmacological opportunities of orally administered nanomedicine delivery
    Darren Michael Moss, Paul Curley, Hannah Kinvig, Clare Hoskins, Andrew Owen
    Expert Review of Gastroenterology & Hepatology.2018; 12(3): 223.     CrossRef
  • AhR activation protects intestinal epithelial barrier function through regulation of Par-6
    Kun Yu, Yuanhang Ma, Zhicao Zhang, Xin Fan, Teming Li, Liangzi Li, Weidong Xiao, Yujiao Cai, Lihua Sun, Pengyuan Xu, Min Yu, Hua Yang
    Journal of Molecular Histology.2018; 49(5): 449.     CrossRef
  • The Role of Macrophage Migration Inhibitory Factor in the Function of Intestinal Barrier
    Milica Vujicic, Tamara Saksida, Sanja Despotovic, Svetlana Sokovic Bajic, Ivana Lalić, Ivan Koprivica, Dragica Gajic, Natasa Golic, Maja Tolinacki, Ivana Stojanovic
    Scientific Reports.2018;[Epub]     CrossRef
  • Predictors and clinical outcomes of follow‐up loss in patients with inflammatory bowel disease
    Dae Hyung Woo, Kyeong Ok Kim, Min Kyu Kang, Si Hyung Lee, Byung Ik Jang, Tae Nyeun Kim
    Journal of Gastroenterology and Hepatology.2018; 33(11): 1834.     CrossRef
  • Protective Effects of Salvianolic Acid A against Dextran Sodium Sulfate-Induced Acute Colitis in Rats
    Kai Wang, Qinqin Yang, Quanxin Ma, Bei Wang, Zhengrui Wan, Minli Chen, Liming Wu
    Nutrients.2018; 10(6): 791.     CrossRef
  • Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases
    Xiong Chen, Rui Liu, Xiaoming Liu, Canxia Xu, Xiaoyan Wang
    BioMed Research International.2018; 2018: 1.     CrossRef
  • Gut Barrier Dysfunction—A Primary Defect in Twins with Crohn’s Disease Predominantly Caused by Genetic Predisposition
    Åsa V Keita, Carl Mårten Lindqvist, Åke Öst, Carlos D L Magana, Ida Schoultz, Jonas Halfvarson
    Journal of Crohn's and Colitis.2018; 12(10): 1200.     CrossRef
  • The role of gastrointestinal permeability in food allergy
    Nazanin Samadi, Martina Klems, Eva Untersmayr
    Annals of Allergy, Asthma & Immunology.2018; 121(2): 168.     CrossRef
  • MicroRNA in gastrointestinal cell signalling
    Priyanka Mishra, Divya Singh, Lilly Ganju, Bhuvnesh Kumar
    Inflammopharmacology.2018; 26(1): 1.     CrossRef
  • Functional sequencing read annotation for high precision microbiome analysis
    Chengsheng Zhu, Maximilian Miller, Srinayani Marpaka, Pavel Vaysberg, Malte C Rühlemann, Guojun Wu, Femke-Anouska Heinsen, Marie Tempel, Liping Zhao, Wolfgang Lieb, Andre Franke, Yana Bromberg
    Nucleic Acids Research.2018; 46(4): e23.     CrossRef
  • Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway
    Dacheng Wu, Keyan Wu, Qingtian Zhu, Weiming Xiao, Qing Shan, Zhigang Yan, Jian Wu, Bin Deng, Yan Xue, Weijuan Gong, Guotao Lu, Yanbing Ding
    Mediators of Inflammation.2018; 2018: 1.     CrossRef
  • The Effect of Prim-O-Glucosylcimifugin on Tryptase-Induced Intestinal Barrier Dysfunction in Caco-2 Cells
    Lu Xu, Jieyi Cai, Aofei Tian, Kai Qian, Renan Qin, Shaoyun Qi, Xupeng Tan, Yuqin Qiu, Mengjuan Gong, Bin Han, Xuguang Hu
    Biological and Pharmaceutical Bulletin.2018; 41(9): 1355.     CrossRef
  • Alopecia areata and the gut—the link opens up for novel therapeutic interventions
    Annika Borde, Annika Åstrand
    Expert Opinion on Therapeutic Targets.2018; 22(6): 503.     CrossRef
  • Effects of Alpinetin on Intestinal Barrier Function, Inflammation and Oxidative Stress in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice
    Yue Tan, Changqing Zheng
    The American Journal of the Medical Sciences.2018; 355(4): 377.     CrossRef
  • IL‐1β induces increased tight junction permeability in bovine mammary epithelial cells via the IL‐1β‐ERK1/2‐MLCK axis upon blood‐milk barrier damage
    Tong Xu, Zhijian Dong, Xixi Wang, Shaopei Qi, Xueru Li, Rui Cheng, Xu Liu, Yong Zhang, Ming‐Qing Gao
    Journal of Cellular Biochemistry.2018; 119(11): 9028.     CrossRef
  • Leaky brain in neurological and psychiatric disorders: Drivers and consequences
    Gerwyn Morris, Brisa S Fernandes, Basant K Puri, Adam J Walker, Andre F Carvalho, Michael Berk
    Australian & New Zealand Journal of Psychiatry.2018; 52(10): 924.     CrossRef
  • Inflammation, Impaired Motility, and Permeability in a Guinea Pig Model of Postoperative Ileus
    Yoo Jin Lee, Zahid Hussain, Cheal Wung Huh, Young Ju Lee, Hyojin Park
    Journal of Neurogastroenterology and Motility.2018; 24(1): 147.     CrossRef
  • Ferulic acid protects against heat stress-induced intestinal epithelial barrier dysfunction in IEC-6 cells via the PI3K/Akt-mediated Nrf2/HO-1 signaling pathway
    Shasha He, Yuhong Guo, Jingxia Zhao, Xiaolong Xu, Jin Song, Ning Wang, Qingquan Liu
    International Journal of Hyperthermia.2018; 35(1): 112.     CrossRef
  • Probiotics and the Gut Immune System: Indirect Regulation
    Giorgio La Fata, Peter Weber, M. Hasan Mohajeri
    Probiotics and Antimicrobial Proteins.2018; 10(1): 11.     CrossRef
  • Pathophysiology of IBD associated diarrhea
    Arivarasu N. Anbazhagan, Shubha Priyamvada, Waddah A. Alrefai, Pradeep K. Dudeja
    Tissue Barriers.2018; 6(2): e1463897.     CrossRef
  • Acid‐Hydrolyzed Gliadins Worsen Food Allergies through Early Sensitization
    Laure Castan, Clélia Villemin, Mathilde Claude, Philippe Aubert, Tony Durand, Michel Neunlist, Chantal Brossard, Antoine Magnan, Marie Bodinier, Grégory Bouchaud
    Molecular Nutrition & Food Research.2018;[Epub]     CrossRef
  • Resveratrol and inflammatory bowel disease: the evidence so far
    Sandra Nunes, Francesca Danesi, Daniele Del Rio, Paula Silva
    Nutrition Research Reviews.2018; 31(1): 85.     CrossRef
  • Molecular mechanisms of somatostatin-mediated intestinal epithelial barrier function restoration by upregulating claudin-4 in mice with DSS-induced colitis
    Lin Cai, Xiao Li, Chong Geng, Xuelian Lei, Chunhui Wang
    American Journal of Physiology-Cell Physiology.2018; 315(4): C527.     CrossRef
  • Micro-patterned endogenous stroma equivalent induces polarized crypt-villus architecture of human small intestinal epithelium
    Vincenza De Gregorio, Giorgia Imparato, Francesco Urciuolo, Paolo A. Netti
    Acta Biomaterialia.2018; 81: 43.     CrossRef
  • Ameliorative effect of Alnus japonica ethanol extract on colitis through the inhibition of inflammatory responses and attenuation of intestinal barrier disruption in vivo and in vitro
    Jin Hua Chi, Young Ho Kim, Dong Hwan Sohn, Geom Seog Seo, Sung Hee Lee
    Biomedicine & Pharmacotherapy.2018; 108: 1767.     CrossRef
  • Microbial Biomarkers of Intestinal Barrier Maturation in Preterm Infants
    Bing Ma, Elias McComb, Pawel Gajer, Hongqiu Yang, Mike Humphrys, Adora C. Okogbule-Wonodi, Alessio Fasano, Jacques Ravel, Rose M Viscardi
    Frontiers in Microbiology.2018;[Epub]     CrossRef
  • Effects of Boswellia Serrata Roxb. and Curcuma longa L. in an In Vitro Intestinal Inflammation Model Using Immune Cells and Caco-2
    Paolo Governa, Maddalena Marchi, Veronica Cocetta, Bianca De Leo, Philippa T. K. Saunders, Daniela Catanzaro, Elisabetta Miraldi, Monica Montopoli, Marco Biagi
    Pharmaceuticals.2018; 11(4): 126.     CrossRef
  • Schistosome Egg Migration: Mechanisms, Pathogenesis and Host Immune Responses
    Alice H. Costain, Andrew S. MacDonald, Hermelijn H. Smits
    Frontiers in Immunology.2018;[Epub]     CrossRef
  • Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals
    Bonggi Lee, Kyoung Mi Moon, Choon Young Kim
    Journal of Immunology Research.2018; 2018: 1.     CrossRef
  • Effects of 17beta;-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model
    Chin-Hee Song, Nayoung Kim, Sung Hwa Sohn, Sun Min Lee, Ryoung Hee Nam, Hee Young Na, Dong Ho Lee, Young-Joon Surh
    Gut and Liver.2018; 12(6): 682.     CrossRef
  • A Rodent Model of Anxiety: The Effect of Perinatal Immune Challenges on Gastrointestinal Inflammation and Integrity
    Sharon L. Hollins, Luke Brock, Rafael Barreto, Lauren Harms, Ariel Dunn, Pedro Garcia-Sobrinho, Jessica Bruce, Phillip W. Dickson, Marjorie M. Walker, Simon Keely, Deborah M. Hodgson
    Neuroimmunomodulation.2018; 25(3): 163.     CrossRef
  • Critical role of Keratin 1 in maintaining epithelial barrier and correlation of its down-regulation with the progression of inflammatory bowel disease
    Xiangqian Dong, Zichao Liu, Danfeng Lan, Junkun Niu, Jiarong Miao, Gang Yang, Fengrui Zhang, Yang Sun, Kunhua Wang, Yinglei Miao
    Gene.2017; 608: 13.     CrossRef
  • Olive oil bioactives protect pigs against experimentally-induced chronic inflammation independently of alterations in gut microbiota
    Martin Liehr, Alessandro Mereu, Jose Javier Pastor, Jose Carlos Quintela, Stefanie Staats, Gerald Rimbach, Ignacio Rodolfo Ipharraguerre, Hauke Smidt
    PLOS ONE.2017; 12(3): e0174239.     CrossRef
  • Intestinal epithelium, intraepithelial lymphocytes and the gut microbiota - Key players in the pathogenesis of celiac disease
    Bożena Cukrowska, Agnieszka Sowińska, Joanna Beata Bierła, Elżbieta Czarnowska, Anna Rybak, Urszula Grzybowska-Chlebowczyk
    World Journal of Gastroenterology.2017; 23(42): 7505.     CrossRef
  • Saccharomyces boulardii CNCM I-745 Restores intestinal Barrier Integrity by Regulation of E-cadherin Recycling
    Chloé Terciolo, Aurélie Dobric, Mehdi Ouaissi, Carole Siret, Gilles Breuzard, Françoise Silvy, Bastien Marchiori, Sébastien Germain, Renaté Bonier, Adel Hama, Roisin Owens, Dominique Lombardo, Véronique Rigot, Frédéric André
    Journal of Crohn's and Colitis.2017; 11(8): 999.     CrossRef
  • Intestinal Barrier Disturbances in Haemodialysis Patients: Mechanisms, Consequences, and Therapeutic Options
    D. S. March, M. P. M. Graham-Brown, C. M. Stover, N. C. Bishop, J. O. Burton
    BioMed Research International.2017; 2017: 1.     CrossRef
  • Protective effects of polyphenol-rich infusions from carob (Ceratonia siliqua) leaves and cladodes of Opuntia ficus-indica against inflammation associated with diet-induced obesity and DSS-induced colitis in Swiss mice
    Ikram Aboura, Abdelhafid Nani, Meriem Belarbi, Babar Murtaza, Aurélie Fluckiger, Adélie Dumont, Chahid Benammar, Moufida Saidani Tounsi, François Ghiringhelli, Mickaël Rialland, Naim Akhtar Khan, Aziz Hichami
    Biomedicine & Pharmacotherapy.2017; 96: 1022.     CrossRef
  • Arsenic downregulates tight junction claudin proteins through p38 and NF-κB in intestinal epithelial cell line, HT-29
    Chang Hee Jeong, Jin Sil Seok, Michael C. Petriello, Sung Gu Han
    Toxicology.2017; 379: 31.     CrossRef
  • Probiotics reduce repeated water avoidance stress-induced colonic microinflammation in Wistar rats in a sex-specific manner
    Ju Yup Lee, Nayoung Kim, Ryoung Hee Nam, Sung Hwa Sohn, Sun Min Lee, Daeun Choi, Hyuk Yoon, Yong Sung Kim, Hye Seung Lee, Dong Ho Lee, Seungil Ro
    PLOS ONE.2017; 12(12): e0188992.     CrossRef
  • The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis
    Dana Elshaer, Jakob Begun
    Seminars in Cell & Developmental Biology.2017; 61: 51.     CrossRef
  • ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
    Yanlei Ma, Jiping Yue, Yao Zhang, Chenzhang Shi, Matt Odenwald, Wenguang G. Liang, Qing Wei, Ajay Goel, Xuewen Gou, Jamie Zhang, Shao-Yu Chen, Wei-Jen Tang, Jerrold R. Turner, Feng Yang, Hong Liang, Huanlong Qin, Xiaoyang Wu
    Nature Communications.2017;[Epub]     CrossRef
  • Role of pregnane X-receptor in regulating bacterial translocation in chronic liver diseases
    Sundhar Mohandas, Balasubramaniyan Vairappan
    World Journal of Hepatology.2017; 9(32): 1210.     CrossRef
  • The effect of age on the intestinal mucus thickness, microbiota composition and immunity in relation to sex in mice
    Marlies Elderman, Bruno Sovran, Floor Hugenholtz, Katrine Graversen, Myrte Huijskes, Eva Houtsma, Clara Belzer, Mark Boekschoten, Paul de Vos, Jan Dekker, Jerry Wells, Marijke Faas, Veena Taneja
    PLOS ONE.2017; 12(9): e0184274.     CrossRef
  • The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases
    Min-Hyun Kim, Hyeyoung Kim
    International Journal of Molecular Sciences.2017; 18(5): 1051.     CrossRef
  • Rebamipide ameliorates radiation-induced intestinal injury in a mouse model
    Sehwan Shim, Hyo-Sun Jang, Hyun-Wook Myung, Jae Kyung Myung, Jin-Kyu Kang, Min-Jung Kim, Seung Bum Lee, Won-Suk Jang, Sun-Joo Lee, Young-Woo Jin, Seung-Sook Lee, Sunhoo Park
    Toxicology and Applied Pharmacology.2017; 329: 40.     CrossRef
  • Acrolein Disrupts Tight Junction Proteins and Causes Endoplasmic Reticulum Stress-Mediated Epithelial Cell Death Leading to Intestinal Barrier Dysfunction and Permeability
    Wei-Yang Chen, Min Wang, Jingwen Zhang, Shirish S. Barve, Craig J. McClain, Swati Joshi-Barve
    The American Journal of Pathology.2017; 187(12): 2686.     CrossRef
  • Mitochondrial ATP Depletion Disrupts Caco-2 Monolayer Integrity and Internalizes Claudin 7
    Lonneke M. JanssenDuijghuijsen, Sander Grefte, Vincent C. J. de Boer, Lara Zeper, Dorien A. M. van Dartel, Inge van der Stelt, Melissa Bekkenkamp-Grovenstein, Klaske van Norren, Harry J. Wichers, Jaap Keijer
    Frontiers in Physiology.2017;[Epub]     CrossRef
  • Oxyresveratrol improves tight junction integrity through the PKC and MAPK signaling pathways in Caco-2 cells
    HyunA Jo, Dahyun Hwang, Jeong-Keun Kim, Young-Hee Lim
    Food and Chemical Toxicology.2017; 108: 203.     CrossRef
  • From clinical uncertainties to precision medicine: the emerging role of the gut barrier and microbiome in small bowel functional diseases
    Wojciech Marlicz, Diana E Yung, Karolina Skonieczna-Żydecka, Igor Loniewski, Saskia van Hemert, Beata Loniewska, Anastasios Koulaouzidis
    Expert Review of Gastroenterology & Hepatology.2017; 11(10): 961.     CrossRef
  • Dietary fibre-based SCFA mixtures promote both protection and repair of intestinal epithelial barrier function in a Caco-2 cell model
    Tingting Chen, Choon Young Kim, Amandeep Kaur, Lisa Lamothe, Maliha Shaikh, Ali Keshavarzian, Bruce R. Hamaker
    Food & Function.2017; 8(3): 1166.     CrossRef
  • Berberine alleviates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress
    Li-Chao Zhang, Yue Wang, Ling-Chang Tong, Sheng Sun, Wei-Ye Liu, Su Zhang, Rong-Mei Wang, Zhi-Bin Wang, Ling Li
    Experimental and Therapeutic Medicine.2017; 13(6): 3374.     CrossRef
  • Dietary Supplementation of Fermented Rice Bran Effectively Alleviates Dextran Sodium Sulfate-Induced Colitis in Mice
    Jahidul Islam, Takuya Koseki, Kouichi Watanabe, Ardiansyah, Slamet Budijanto, Akira Oikawa, Md Alauddin, Tomoko Goto, Hisahi Aso, Michio Komai, Hitoshi Shirakawa
    Nutrients.2017; 9(7): 747.     CrossRef
  • Petri Net-Based Model of Helicobacter pylori Mediated Disruption of Tight Junction Proteins in Stomach Lining during Gastric Carcinoma
    Anam Naz, Ayesha Obaid, Faryal M. Awan, Aqsa Ikram, Jamil Ahmad, Amjad Ali
    Frontiers in Microbiology.2017;[Epub]     CrossRef
  • The Effects of Direct-fed Microbial Supplementation, as an Alternative to Antibiotics, on Growth Performance, Intestinal Immune Status, and Epithelial Barrier Gene Expression in Broiler Chickens
    U. Gadde, S. T. Oh, Y. S. Lee, E. Davis, N. Zimmerman, T. Rehberger, Hyun S. Lillehoj
    Probiotics and Antimicrobial Proteins.2017; 9(4): 397.     CrossRef
  • Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers
    Judit Váradi, András Harazin, Ferenc Fenyvesi, Katalin Réti-Nagy, Péter Gogolák, György Vámosi, Ildikó Bácskay, Pálma Fehér, Zoltán Ujhelyi, Gábor Vasvári, Eszter Róka, David Haines, Mária A. Deli, Miklós Vecsernyés, Zoltán Rakonczay
    PLOS ONE.2017; 12(1): e0170537.     CrossRef
  • Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model
    Jie Han, Ji-Hong Li, Guang Bai, Guo-Shun Shen, Jing Chen, Jia-Nan Liu, Shuo Wang, Xian-Jun Liu
    World Journal of Gastroenterology.2017; 23(12): 2175.     CrossRef
  • Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development
    Obinna C. Ubah, John Steven, Marina Kovaleva, Laura Ferguson, Charlotte Barelle, Andrew J. R. Porter, Caroline J. Barelle
    Frontiers in Immunology.2017;[Epub]     CrossRef
  • Genetic variation and expression levels of tight junction genes identifies association between MAGI3 and inflammatory bowel disease
    Elisabeth Norén, Sven Almer, Jan Söderman
    BMC Gastroenterology.2017;[Epub]     CrossRef
  • Protective effect of sugar cane extract against dextran sulfate sodium-induced colonic inflammation in mice
    Bin Wang, Yansen Li, Masami Mizu, Toma Furuta, ChunMei Li
    Tissue and Cell.2017; 49(1): 8.     CrossRef
  • Wasabia japonica is a potential functional food to prevent colitis via inhibiting the NF-κB signaling pathway
    Ju-Hee Kang, Seungho Choi, Jeong-Eun Jang, Prakash Ramalingam, Young Tag Ko, Sun Yeou Kim, Seung Hyun Oh
    Food & Function.2017; 8(8): 2865.     CrossRef
  • Temporal and regional intestinal changes in permeability, tight junction, and cytokine gene expression following ovariectomy-induced estrogen deficiency
    Fraser L. Collins, Naiomy D. Rios-Arce, Shelby Atkinson, Hayley Bierhalter, Daniel Schoenherr, Jason N. Bazil, Laura R. McCabe, Narayanan Parameswaran
    Physiological Reports.2017; 5(9): e13263.     CrossRef
  • IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression
    Yaya Wang, John Brian Mumm, Ronald Herbst, Roland Kolbeck, Yue Wang
    The Journal of Immunology.2017; 199(9): 3316.     CrossRef
  • Chlorogenic acid suppresses lipopolysaccharide-induced nitric oxide and interleukin-1β expression by inhibiting JAK2/STAT3 activation in RAW264.7 cells
    Sang-Hun Kim, Sun-Young Park, Young-Lan Park, Dae-Seong Myung, Jong-Sun Rew, Young-Eun Joo
    Molecular Medicine Reports.2017; 16(6): 9224.     CrossRef
  • Western diet enhances intestinal tumorigenesis in Min/+ mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity
    Mikael Niku, Anne-Maria Pajari, Laura Sarantaus, Essi Päivärinta, Markus Storvik, Anu Heiman-Lindh, Santeri Suokas, Minna Nyström, Marja Mutanen
    The Journal of Nutritional Biochemistry.2017; 39: 126.     CrossRef
  • Effect of Conjugated Linoleic Acid-enriched Butter After 24 hours of Intestinal Mucositis Induction
    Patrícia Aparecida Vieira de Barros, Simone de Vasconcelos Generoso, Maria Emília Rabelo Andrade, Marco Antonio Sundfeld da Gama, Fernando Cesar Ferraz Lopes, Éricka Lorenna de Sales e Souza, Flaviano dos Santos Martins, Sued Eustáquio Mendes Miranda, Sim
    Nutrition and Cancer.2017; 69(1): 168.     CrossRef
  • Regulation of intestinal permeability: The role of proteases
    Hanne Van Spaendonk, Hannah Ceuleers, Leonie Witters, Eveline Patteet, Jurgen Joossens, Koen Augustyns, Anne-Marie Lambeir, Ingrid De Meester, Joris G De Man, Benedicte Y De Winter
    World Journal of Gastroenterology.2017; 23(12): 2106.     CrossRef
  • Animal models for studying epithelial barriers in neonatal necrotizing enterocolitis, inflammatory bowel disease and colorectal cancer
    Tiaosi Xing, Rolando Camacho Salazar, Yan-Hua Chen
    Tissue Barriers.2017; 5(4): e1356901.     CrossRef
  • Variants of β-casofensin, a bioactive milk peptide, differently modulate the intestinal barrier: In vivo and ex vivo studies in rats
    Jérémie Bruno, Aurélie Nicolas, Sandra Pesenti, Jessica Schwarz, Jean-Luc Simon, Joëlle Léonil, Pascale Plaisancié
    Journal of Dairy Science.2017; 100(5): 3360.     CrossRef
  • The Yin and Yang of bile acid action on tight junctions in a model colonic epithelium
    Jayashree Sarathy, Sally Jo Detloff, Mei Ao, Nabihah Khan, Sydney French, Hafsa Sirajuddin, Tanushree Nair, Mrinalini C. Rao
    Physiological Reports.2017;[Epub]     CrossRef
  • Dietary Propolis Ameliorates Dextran Sulfate Sodium-Induced Colitis and Modulates the Gut Microbiota in Rats Fed a Western Diet
    Kai Wang, Xiaolu Jin, Mengmeng You, Wenli Tian, Richard Leu, David Topping, Michael Conlon, Liming Wu, Fuliang Hu
    Nutrients.2017; 9(8): 875.     CrossRef
  • Helicobacter suis induces changes in gastric inflammation and acid secretion markers in pigs of different ages
    C. De Witte, B. Devriendt, B. Flahou, I. Bosschem, R. Ducatelle, A. Smet, F. Haesebrouck
    Veterinary Research.2017;[Epub]     CrossRef
  • Vitamin D3 induces vitamin D receptor and HDAC11 binding to relieve the promoter of the tight junction proteins
    Feng-Hua Liu, Shan-Shan Li, Xiao-Xi Li , Shuai Wang , Mao-Gang Li , Li Guan, Tian-Gang Luan, Zhi-Gang Liu, Zhan-Ju Liu, Ping-Chang Yang
    Oncotarget.2017; 8(35): 58781.     CrossRef
  • Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway
    Zhongze Liu, Liangzi Li, Weigang Chen, Qimeng Wang, Weidong Xiao, Yuanhang Ma, Baifa Sheng, Xiang Li, Lihua Sun, Min Yu, Hua Yang
    International Journal of Molecular Medicine.2017;[Epub]     CrossRef
  • The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists
    Sunil Thomas, Jacques Izard, Emily Walsh, Kristen Batich, Pakawat Chongsathidkiet, Gerard Clarke, David A. Sela, Alexander J. Muller, James M. Mullin, Korin Albert, John P. Gilligan, Katherine DiGuilio, Rima Dilbarova, Walker Alexander, George C. Prenderg
    Cancer Research.2017; 77(8): 1783.     CrossRef
  • The prevalence of bacterial overgrowth syndrome and its associated factors in patients with inflammatory bowel diseases (according to the data of the Novosibirsk registry)
    Yu A Kulygina, M F Osipenko, M I Skalinskaya, K D Palchunova
    Terapevticheskii arkhiv.2017; 89(2): 15.     CrossRef
  • The Effect of DA-6034 on Intestinal Permeability in an Indomethacin-Induced Small Intestinal Injury Model
    Dong Shin Kwak, Oh Young Lee, Kang Nyeong Lee, Dae Won Jun, Hang Lak Lee, Byung Chul Yoon, Ho Soon Choi
    Gut and Liver.2016;[Epub]     CrossRef
  • Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces
    Loubna Abdel Hadi, Clara Di Vito, Laura Riboni
    Mediators of Inflammation.2016; 2016: 1.     CrossRef
  • Size-dependent nanoparticulate drug delivery in inflammatory bowel diseases
    John Youshia, Alf Lamprecht
    Expert Opinion on Drug Delivery.2016; 13(2): 281.     CrossRef
  • Lactobacillus acidophilusstimulates intestinal P-glycoprotein expression via a c-Fos/c-Jun-dependent mechanism in intestinal epithelial cells
    Shubha Priyamvada, Arivarasu N. Anbazhagan, Anoop Kumar, Vikas Soni, Waddah A. Alrefai, Ravinder K. Gill, Pradeep K. Dudeja, Seema Saksena
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2016; 310(8): G599.     CrossRef
  • Hydrogen sulfide improves colonic barrier integrity in DSS-induced inflammation in Caco-2 cells and mice
    Hongyu Zhao, Rui Yan, Xiaogang Zhou, Fang Ji, Bing Zhang
    International Immunopharmacology.2016; 39: 121.     CrossRef
  • Advances in nutritional therapy in inflammatory bowel diseases: Review
    Andrzej Wędrychowicz
    World Journal of Gastroenterology.2016; 22(3): 1045.     CrossRef
  • WISP1 Is Increased in Intestinal Mucosa and Contributes to Inflammatory Cascades in Inflammatory Bowel Disease
    Qi Zhang, Cuiping Zhang, Xiaoyu Li, Yanan Yu, Kun Liang, Xinzhi Shan, Kun Zhao, Qinghui Niu, Zibin Tian
    Disease Markers.2016; 2016: 1.     CrossRef
  • Tight Junction Disruption Induced by Type 3 Secretion System Effectors Injected by Enteropathogenic and Enterohemorrhagic Escherichia coli
    Paul Ugalde-Silva, Octavio Gonzalez-Lugo, Fernando Navarro-Garcia
    Frontiers in Cellular and Infection Microbiology.2016;[Epub]     CrossRef
  • Effects of Supplementation of the Synbiotic Ecologic® 825/FOS P6 on Intestinal Barrier Function in Healthy Humans: A Randomized Controlled Trial
    E. Wilms, J. Gerritsen, H. Smidt, I. Besseling-van der Vaart, G. T. Rijkers, A. R. Garcia Fuentes, A. A. M. Masclee, F. J. Troost, John Green
    PLOS ONE.2016; 11(12): e0167775.     CrossRef
  • Adherens Junctions Modulate Diffusion between Epithelial Cells inTrichoplax adhaerens
    Carolyn L. Smith, Thomas S. Reese
    The Biological Bulletin.2016; 231(3): 216.     CrossRef
  • The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity
    Romina Fiorotto, Ambra Villani, Antonis Kourtidis, Roberto Scirpo, Mariangela Amenduni, Peter J. Geibel, Massimiliano Cadamuro, Carlo Spirli, Panos Z. Anastasiadis, Mario Strazzabosco
    Hepatology.2016; 64(6): 2118.     CrossRef
  • Curcumin as a therapeutic agent in the chemoprevention of inflammatory bowel disease
    Remya Sreedhar, Somasundaram Arumugam, Rajarajan A. Thandavarayan, Vengadeshprabhu Karuppagounder, Kenichi Watanabe
    Drug Discovery Today.2016; 21(5): 843.     CrossRef
  • Proteinaceous Molecules Mediating Bifidobacterium-Host Interactions
    Lorena Ruiz, Susana Delgado, Patricia Ruas-Madiedo, Abelardo Margolles, Borja Sánchez
    Frontiers in Microbiology.2016;[Epub]     CrossRef
  • Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome
    Bárbara S. Rocha, Carla Nunes, João Laranjinha
    The International Journal of Biochemistry & Cell Biology.2016; 81: 393.     CrossRef
  • Oral immune therapy: targeting the systemic immune system via the gut immune system for the treatment of inflammatory bowel disease
    Yaron Ilan
    Clinical & Translational Immunology.2016;[Epub]     CrossRef
  • Matricellular Protein Periostin Mediates Intestinal Inflammation through the Activation of Nuclear Factor κB Signaling
    Seong-Joon Koh, Younjeong Choi, Byeong Gwan Kim, Kook Lae Lee, Dae Woo Kim, Jung Ho Kim, Ji Won Kim, Joo Sung Kim, Emiko Mizoguchi
    PLOS ONE.2016; 11(2): e0149652.     CrossRef
  • Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice
    Jing Xiong, Ming-feng Zhou, Ya-dong Wang, Li-ping Chen, Wan-fu Xu, Yao-dong Wang, Fan Deng, Si-de Liu
    Scientific Reports.2016;[Epub]     CrossRef
  • Effect of Long Noncoding RNA H19 Overexpression on Intestinal Barrier Function and Its Potential Role in the Pathogenesis of Ulcerative Colitis
    Shan-wen Chen, Peng-yuan Wang, Yu-cun Liu, Lie Sun, Jing Zhu, Shuai Zuo, Ju Ma, Teng-yu Li, Jun-ling Zhang, Guo-wei Chen, Xin Wang, Qiu-ru Zhu, You-wen Zheng, Ze-yang Chen, Zi-hao Yao, Yi-sheng Pan
    Inflammatory Bowel Diseases.2016; 22(11): 2582.     CrossRef
  • Propionate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress
    Ling-chang Tong, Yue Wang, Zhi-bin Wang, Wei-ye Liu, Sheng Sun, Ling Li, Ding-feng Su, Li-chao Zhang
    Frontiers in Pharmacology.2016;[Epub]     CrossRef
  • Arctigenin fromFructus Arctii(Seed of Burdock) Reinforces Intestinal Barrier Function in Caco-2 Cell Monolayers
    Hee Soon Shin, Sun Young Jung, Su Yeon Back, Jeong-Ryong Do, Dong-Hwa Shon
    Evidence-Based Complementary and Alternative Medicine.2015; 2015: 1.     CrossRef
  • Polymorphisms inPRKCDBP, a Transcriptional Target of TNF-α, Are Associated With Inflammatory Bowel Disease in Korean
    Jung-Wook Kim, Chang Kyun Lee, Hyo Jong Kim, Jae-Jun Shim, Jae Young Jang, Seok Ho Dong, Byung-Ho Kim, Young Woon Chang, Sung-Gil Chi
    Intestinal Research.2015; 13(3): 242.     CrossRef
  • Soluble Syndecan-1: Does This Biomarker Address a Seemingly Insoluble Problem in Inflammatory Bowel Disease?
    Angela M. Patterson
    Digestive Diseases and Sciences.2015; 60(8): 2222.     CrossRef
  • Tight junction disruption:Helicobacter pyloriand dysregulation of the gastric mucosal barrier
    Tyler J Caron
    World Journal of Gastroenterology.2015; 21(40): 11411.     CrossRef
  • Nutritional Keys for Intestinal Barrier Modulation
    Stefania De Santis, Elisabetta Cavalcanti, Mauro Mastronardi, Emilio Jirillo, Marcello Chieppa
    Frontiers in Immunology.2015;[Epub]     CrossRef
  • Pathogen Resistance Mediated by IL-22 Signaling at the Epithelial–Microbiota Interface
    Fernanda Schreiber, Julia Maryam Arasteh, Trevor D. Lawley
    Journal of Molecular Biology.2015; 427(23): 3676.     CrossRef
  • Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut
    Andrea Michielan, Renata D’Incà, Hannes Neuwirt
    Mediators of Inflammation.2015;[Epub]     CrossRef
  • Therapies from Fucoidan: An Update
    Janet Fitton, Damien Stringer, Samuel Karpiniec
    Marine Drugs.2015; 13(9): 5920.     CrossRef
  • Drug Release and Targeting: the Versatility of Polymethacrylate Nanoparticles for Peroral Administration Revealed by Using an Optimized In Vitro-Toolbox
    Susanne Beyer, Aline Moosmann, Astrid S. Kahnt, Thomas Ulshöfer, Michael J. Parnham, Nerea Ferreirós, Sylvia Wagner, Matthias G. Wacker
    Pharmaceutical Research.2015; 32(12): 3986.     CrossRef
  • Arginyl-glutamine dipeptide attenuates experimental colitis by enhancing antioxidant function and inhibiting nuclear factor-kappaB
    Hua Yu, Mingjun Dong, Yidong Xu, Ning He, Xiaoyu Dai, Keqiang Li
    RSC Advances.2015; 5(112): 92008.     CrossRef
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Intestinal Stricture in Crohn's Disease
Chen-Wang Chang, Jau-Min Wong, Chien-Chih Tung, I-Lun Shih, Horng-Yuan Wang, Shu-Chen Wei
Intest Res 2015;13(1):19-26.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.19
AbstractAbstract PDFPubReader

Crohn's disease (CD) is a disease with chronic inflammation of unknown etiology involving any part of the gastrointestinal tract. The incidence and prevalence of CD are increasing recently in Asia. Half of the CD patients will have intestinal complications, such as strictures or fistulas, within 20 years after diagnosis. Twenty-five percentage of CD patients have had at least one small bowel stricture and 10% have had at least one colonic stricture and lead to significant complications. Most of these patients will require at least one surgery during their lifetime. Early diagnosis and evaluation with adequate managements for the patients can prevent disability and mortality of these patient. Here, we reviewed the current incidence of CD with stricture, the etiology of stricture, and how to diagnose and manage the stricture.

Citations

Citations to this article as recorded by  
  • Duodenal Crohn’s disease: Case report and systematic review
    Muniratu Amadu, Jonathan Soldera
    World Journal of Methodology.2024;[Epub]     CrossRef
  • Infective Endocarditis After Endoscopic Stricture Dilation in Crohn's Disease
    André Gonçalves, Sandra Barbeiro, Carina Leal, Antonieta Santos, Helena Vasconcelos
    ACG Case Reports Journal.2024; 11(6): e01377.     CrossRef
  • Association between nutritional status assessed by body mass index and Crohn's disease phenotype: A Nation-wide analysis
    Judwin Ndzo, Sudheer K. Vuyyuru, Thomas Trimble, Kaung Yan, Grazziela Figueredo, Gordon W. Moran
    Clinical Nutrition ESPEN.2024; 64: 290.     CrossRef
  • Perioperative optimization of Crohn's disease
    Chun‐Chi Lin, Hung‐Hsin Lin, Hui‐Chuen Chen, Nai‐Chia Chen, I‐Lun Shih, Ji‐Shiang Hung, Te‐Cheng Yueh, Feng‐Fan Chiang, Ping‐Wei Lin, Yuan‐Yao Tsai, Shu‐Chen Wei
    Annals of Gastroenterological Surgery.2023; 7(1): 10.     CrossRef
  • Treatment escalation and de-escalation decisions in Crohn’s disease: Delphi consensus recommendations from Japan, 2021
    Hiroshi Nakase, Motohiro Esaki, Fumihito Hirai, Taku Kobayashi, Katsuyoshi Matsuoka, Minoru Matsuura, Makoto Naganuma, Masayuki Saruta, Kiichiro Tsuchiya, Motoi Uchino, Kenji Watanabe, Tadakazu Hisamatsu, Akira Andoh, Shigeki Bamba, Motohiro Esaki, Mikihi
    Journal of Gastroenterology.2023; 58(4): 313.     CrossRef
  • Ileocecal valve that cannot be intubated in Crohn’s disease: is this a sign of poor prognosis?
    Muhammed Bahaddin Durak, Cem Simsek, Bayram İnan, Ilhami Yuksel
    International Journal of Colorectal Disease.2023;[Epub]     CrossRef
  • Effects of Mimosa caesalpiniifolia pre-formulation on the intestinal barrier during sodium dextran sulfate-induced colitis in Wistar rats
    Aline Garnevi-Fávero , Karina Nascimento-da Silva , Willian Rodrigues-Ribeiro , Caroline Marcantonio-Ferreira , Patrícia Sartorelli, Leonardo Cardili, Rita De Cássia-Sinigaglia , Joice Naiara Bertaglia-Pereira, Marcelo Aparecido-da Silva , Wagner Vilega
    Biomédica.2023; 43(2): 282.     CrossRef
  • Small Bowel Imaging from Stepchild of Roentgenology to MR Enterography: Part I: Guidance in Performing and Observing Normal and Abnormal Imaging Findings
    Antonio Pierro, Laura Maria Minordi, Luigi Larosa, Giulia Guerri, Alessandro Grimaldi, Fabio Quinto, Fabio Rotondi, Annalisa Marcellino, Teresa Bevere, Raffaella Basilico, Roberto Iezzi, Savino Cilla
    Life.2023; 13(8): 1691.     CrossRef
  • Small Bowel Imaging from Stepchild of Roentgenology to MR Enterography, Part II: The Reliable Disclosure of Crohn’s Disease and Non-Inflammatory Small Bowel Disorder Plot through MRI Findings
    Antonio Pierro, Laura Maria Minordi, Luigi Larosa, Carla Cipri, Giulia Guerri, Fabio Quinto, Fabio Rotondi, Annalisa Marcellino, Raffaella Basilico, Roberto Iezzi, Savino Cilla
    Life.2023; 13(9): 1836.     CrossRef
  • Use of oral diet and nutrition support in management of stricturing and fistulizing Crohn's disease
    Kush Fansiwala, Neha D. Shah, Kelly A. McNulty, Mary R. Kwaan, Berkeley N. Limketkai
    Nutrition in Clinical Practice.2023; 38(6): 1282.     CrossRef
  • Congenital Partial Colonic Agenesis in Dogs and Cats: Clinical, Biological, Diagnostic Imaging, Endoscopic and Histopathologic Characterization, a Retrospective Study
    Paul Remmel, Lucile Gros, Jérémy Mortier, Valérie Freiche
    Veterinary Sciences.2023; 10(9): 577.     CrossRef
  • Revisiting fibrosis in inflammatory bowel disease: the gut thickens
    Silvia D’Alessio, Federica Ungaro, Daniele Noviello, Sara Lovisa, Laurent Peyrin-Biroulet, Silvio Danese
    Nature Reviews Gastroenterology & Hepatology.2022; 19(3): 169.     CrossRef
  • Medical treatment of intestinal Crohn's disease
    Eula Plana Tetangco, Adam C. Stein
    Seminars in Colon and Rectal Surgery.2022; 33(1): 100862.     CrossRef
  • Choosing the right biologic for complications of inflammatory bowel disease
    Shana Rakowsky, Konstantinos Papamichael, Adam S. Cheifetz
    Expert Review of Gastroenterology & Hepatology.2022; 16(3): 235.     CrossRef
  • The Possible Pathogenic Role of IgG4-Producing Plasmablasts in Stricturing Crohn’s Disease
    Omar Bushara, David Joseph Escobar, Samuel Edward Weinberg, Leyu Sun, Jie Liao, Guang-Yu Yang
    Pathobiology.2022; 89(4): 187.     CrossRef
  • Safety and efficacy of non-fluoroscopic endoscopic dilatation of gastrointestinal tuberculosis related strictures
    Pankaj Kumar, Anuraag Jena, Chhagan Lal Birda, Harjeet Singh, Pankaj Gupta, Kaushal Kishor Prasad, Usha Dutta, Vishal Sharma
    BMC Gastroenterology.2022;[Epub]     CrossRef
  • Endoscopic balloon dilations for strictures of rectum, ileocecal valve and duodenum in a patient with X-linked inhibitor of apoptosis deficiency: a case report
    Shinsuke Otagiri, Takehiko Katsurada, Kensuke Sakurai, Junichi Sugita, Naoya Sakamoto
    Intestinal Research.2022; 20(2): 274.     CrossRef
  • State-of-the-art surgery for Crohn’s disease: Part II—colonic Crohn’s disease and associated neoplasms
    Anne Macleod, Sandra L. Kavalukas, Katharina M. Scheurlen, Susan Galandiuk
    Langenbeck's Archives of Surgery.2022; 407(7): 2595.     CrossRef
  • The role of interleukin-33 in organ fibrosis
    Samuele Di Carmine, Molly M Scott, Mairi H McLean, Henry J McSorley
    Discovery Immunology.2022;[Epub]     CrossRef
  • Late onset crohns ileitis—A diagnostic dilemma
    Ashok Sunder, Manish Kumar, Sudip Saha, Bhagyalakshmi Satyanarayan
    Journal of Family Medicine and Primary Care.2022; 11(12): 7968.     CrossRef
  • Inhibition of APE1/Ref-1 Redox Signaling Alleviates Intestinal Dysfunction and Damage to Myenteric Neurons in a Mouse Model of Spontaneous Chronic Colitis
    Lauren Sahakian, Rhiannon T Filippone, Rhian Stavely, Ainsley M Robinson, Xu Sean Yan, Raquel Abalo, Rajaraman Eri, Joel C Bornstein, Mark R Kelley, Kulmira Nurgali
    Inflammatory Bowel Diseases.2021; 27(3): 388.     CrossRef
  • A postdischarge venous thromboembolism risk calculator for inflammatory bowel disease surgery
    Cary Jo R. Schlick, Tarik K. Yuce, Anthony D. Yang, Michael F. McGee, David J. Bentrem, Karl Y. Bilimoria, Ryan P. Merkow
    Surgery.2021; 169(2): 240.     CrossRef
  • Presence of Obstructive Symptoms and Absence of Perianal Crohn Disease Is Predictive of Surgery After Endoscopic Balloon Dilation
    Barathi Sivasailam, Scott Manski, Alicia Wentz, Raymond K Cross
    Inflammatory Bowel Diseases.2021; 27(8): 1230.     CrossRef
  • Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease
    Allison D Ta, Nicholas J Ollberding, Rebekah Karns, Yael Haberman, Adina L Alazraki, David Hercules, Robert Baldassano, James Markowitz, Melvin B Heyman, Sandra Kim, Barbara Kirschner, Jason M Shapiro, Joshua Noe, Maria Oliva-Hemker, Anthony Otley, Marian
    Inflammatory Bowel Diseases.2021; 27(11): 1707.     CrossRef
  • Infliximab therapy intensification based on endoscopic activity is related to suppress treatment discontinuation in patients with Crohn disease
    Yuga Komaki, Shuji Kanmura, Kazuki Yutsudo, Kosuke Kuwazuru, Fukiko Komaki, Akihito Tanaka, Nobuaki Nishimata, Yoichi Sameshima, Fumisato Sasaki, Hidehisa Ohi, Yuichi Nakamura, Koichi Tokushige, Yukinori Sameshima, Akio Ido
    Medicine.2021; 100(6): e24731.     CrossRef
  • Duodenal Obstruction in a Patient Previously Treated With EndoVascular Aneurysm Sealing System Repair
    Carlo Biddau, Carlo Nagliati, Michele Graziano, Lorenzo Cereser, Giovanni Terrosu, Alessandro Balani
    Vascular and Endovascular Surgery.2021; 55(8): 859.     CrossRef
  • Crohn's Disease Obstructions
    Molly M. Ford
    Clinics in Colon and Rectal Surgery.2021; 34(04): 227.     CrossRef
  • Transplantation of fecal microbiota from patients with inflammatory bowel disease and depression alters immune response and behavior in recipient mice
    Hyo-Min Jang, Jeon-Kyung Kim, Min-Kyung Joo, Yoon-Jung Shin, Chang Kyun Lee, Hyo-Jong Kim, Dong-Hyun Kim
    Scientific Reports.2021;[Epub]     CrossRef
  • Crohn’s disease at radiological imaging: focus on techniques and intestinal tract
    Giuseppe Cicero, Silvio Mazziotti
    Intestinal Research.2021; 19(4): 365.     CrossRef
  • Current Topics of the Mechanism of Intestinal Fibrosis in Crohn’s Disease
    Yusuke Honzawa, Shuji Yamamoto, Makoto Okabe, Hiroshi Seno, Hiroshi Nakase
    Immuno.2021; 1(4): 574.     CrossRef
  • Worse outcomes and higher costs of care in fibrostenotic Crohn’s disease: a real-world propensity-matched analysis in the USA
    Melody Dehghan, Gabriel Wong, Edward Neuberger, Cindy Kin, Florian Rieder, K T Park
    BMJ Open Gastroenterology.2021; 8(1): e000781.     CrossRef
  • Epidemiology of fibrostenosing inflammatory bowel disease
    Joyce Wing Yan Mak, Siew Chien Ng
    Journal of Digestive Diseases.2020; 21(6): 332.     CrossRef
  • The Efficacy of Anti-Tumor Necrosis Factor Alpha for Symptomatic Stricturing Small Bowel Crohn’s Disease
    Mansour Alourfi, Mahmoud Mosli, Omar I Saadah
    Cureus.2020;[Epub]     CrossRef
  • Roles of protein ubiquitination in inflammatory bowel disease
    Yue Xiao, Qi Huang, Zherui Wu, Weilin Chen
    Immunobiology.2020; 225(6): 152026.     CrossRef
  • Chirurgie des maladies inflammatoires chroniques de l’intestin
    M. Aubert, D. Mege, L. Maggiori, Y. Panis
    EMC - Gastro-entérologie.2020; 37(3): 1.     CrossRef
  • Development, validation, and application of a novel tool to measure disease-related knowledge in patients with inflammatory bowel disease
    Hyuk Yoon, Suk-Kyun Yang, Hoonsub So, Ko Eun Lee, Sang Hyoung Park, Sung-Ae Jung, Joong Haeng Choh, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee
    The Korean Journal of Internal Medicine.2019; 34(1): 81.     CrossRef
  • Unusual causes of large bowel obstruction
    Nicholas G. Farkas, Ted Joseph P. Welman, Talisa Ross, Sarah Brown, Jason J. Smith, Nikhil Pawa
    Current Problems in Surgery.2019; 56(2): 49.     CrossRef
  • TTC7A: Steward of Intestinal Health
    Sasha Jardine, Neel Dhingani, Aleixo M. Muise
    Cellular and Molecular Gastroenterology and Hepatology.2019; 7(3): 555.     CrossRef
  • Segmental dilatation following side‐to‐side isoperistaltic strictureplasty in Crohn’s disease: a note of caution
    Brendan Desmond, Ashok Gunawardene, Ben Griffiths, John Keating
    ANZ Journal of Surgery.2019;[Epub]     CrossRef
  • Small bowel strictures
    Deniz Durmush, Arthur J. Kaffes
    Current Opinion in Gastroenterology.2019; 35(3): 235.     CrossRef
  • Early Initiation of Anti-TNF is Associated with Favourable Long-term Outcome in Crohn’s Disease: 10-Year-Follow-up Data from the Swiss IBD Cohort Study
    Roy Frei, Nicolas Fournier, Jonas Zeitz, Michael Scharl, Bernhard Morell, Thomas Greuter, Philipp Schreiner, Benjamin Misselwitz, Ekaterina Safroneeva, Alain M Schoepfer, Stephan R Vavricka, Gerhard Rogler, Luc Biedermann
    Journal of Crohn's and Colitis.2019; 13(10): 1292.     CrossRef
  • Clinical Features and Prognosis of Crohn’s Disease with Upper Gastrointestinal Tract Phenotype in Chinese Patients
    Xiao-Wei Sun, Juan Wei, Zhao Yang, Xin-Xin Jin, Hai-Jun Wan, Bo-Si Yuan, Miao-Fang Yang, Jiong Liu, Fang-Yu Wang
    Digestive Diseases and Sciences.2019; 64(11): 3291.     CrossRef
  • Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency
    Young Lo, Jean Philippe Sauve, Susan C. Menzies, Theodore S. Steiner, Laura M. Sly
    Mucosal Immunology.2019; 12(5): 1187.     CrossRef
  • Occult Adenocarcinoma Arising in Crohn’s-Related Strictures: A Case Series
    Kevin Singh, Amandeep Singh, Jessica Philpott, David Liska, Keith Lai
    Crohn's & Colitis 360.2019;[Epub]     CrossRef
  • Agentes anti-factor de necrosis tumoral en enfermedad de Crohn y colitis ulcerosa: más allá de la enfermedad luminal
    Laura Núñez-Gómez, Francisco Mesonero-Gismero, Agustín Albillos-Martínez, Antonio López-Sanromán
    Gastroenterología y Hepatología.2018; 41(9): 576.     CrossRef
  • Parathyroid Hormone–Like Hormone Induces Epithelial-to-Mesenchymal Transition of Intestinal Epithelial Cells by Activating the Runt-Related Transcription Factor 2
    Shuying He, Minmin Xue, Cuiping Liu, Fang Xie, Lan Bai
    The American Journal of Pathology.2018; 188(6): 1374.     CrossRef
  • Anti-tumour necrosis factor agents in Crohn's disease and ulcerative colitis: Beyond luminal disease
    Laura Núñez-Gómez, Francisco Mesonero-Gismero, Agustín Albillos-Martínez, Antonio López-Sanromán
    Gastroenterología y Hepatología (English Edition).2018; 41(9): 576.     CrossRef
  • Long-Term Outcomes of Endoscopic Balloon Dilation for Benign Strictures in Patients with Inflammatory Bowel Disease
    Hye Won Lee, Soo Jung Park, Seong Ran Jeon, Byong Duk Ye, Jae Jun Park, Jae Hee Cheon, Tae Il Kim, Won Ho Kim
    Gut and Liver.2018; 12(5): 530.     CrossRef
  • Association of Perianal Fistulas with Clinical Features and Prognosis of Crohn's Disease in Korea: Results from the CONNECT Study
    Jaeyoung Chun, Jong Pil Im, Ji Won Kim, Kook Lae Lee, Chang Hwan Choi, Hyunsoo Kim, Jae Hee Cheon, Byong Duk Ye, Young-Ho Kim, You Sun Kim, Yoon Tae Jeen, Dong Soo Han, Won Ho Kim, Joo Sung Kim
    Gut and Liver.2018; 12(5): 544.     CrossRef
  • Computed tomography and magnetic resonance imaging in the diagnosis of the small and large intestine strictures in Crohn’s disease. Radiological semiotics and assessment of the inflammation activity
    S. E. Dubrova, G. A. Stashuk, N. V. Nikitina, Yu. K. Bogomazov
    Almanac of Clinical Medicine.2018; 46(7): 725.     CrossRef
  • A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn’s disease patients
    Andrew Y. F. Li Yim, Jessica R. de Bruyn, Nicolette W. Duijvis, Catriona Sharp, Enrico Ferrero, Wouter J. de Jonge, Manon E. Wildenberg, Marcel M. A. M. Mannens, Christianne J. Buskens, Geert R. D’Haens, Peter Henneman, Anje A. te Velde, Osman El-Maarri
    PLOS ONE.2018; 13(12): e0209656.     CrossRef
  • Management of Crohn's disease in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease
    Shu-Chen Wei, Ting-An Chang, Te-Hsin Chao, Jinn-Shiun Chen, Jen-Wei Chou, Yenn-Hwei Chou, Chiao-Hsiung Chuang, Wen-Hung Hsu, Tien-Yu Huang, Tzu-Chi Hsu, Chun-Chi Lin, Hung-Hsin Lin, Jen-Kou Lin, Wei-Chen Lin, Yen-Hsuan Ni, Ming-Jium Shieh, I-Lun Shih, Chi
    Intestinal Research.2017; 15(3): 285.     CrossRef
  • Biodegradable Stents
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  • Quality Indicators for Small Bowel Capsule Endoscopy
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    Clinical Endoscopy.2017; 50(2): 148.     CrossRef
  • Editorial: Factors Promoting Development of Fibrosis in Crohn’s Disease
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    Frontiers in Medicine.2017;[Epub]     CrossRef
  • Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease
    Diana Hoang-Ngoc Tran, Jiani Wang, Christina Ha, Wendy Ho, S. Anjani Mattai, Angelos Oikonomopoulos, Guy Weiss, Precious Lacey, Michelle Cheng, Christine Shieh, Caroline C. Mussatto, Samantha Ho, Daniel Hommes, Hon Wai Koon
    BMC Gastroenterology.2017;[Epub]     CrossRef
  • Advanced Oxidation Protein Products Induce Epithelial–Mesenchymal Transition of Intestinal Epithelial Cellsviaa PKC δ-Mediated, Redox-Dependent Signaling Pathway
    Xiaoping Xu, Shibo Sun, Fang Xie, Juanjuan Ma, Jing Tang, Shuying He, Lan Bai
    Antioxidants & Redox Signaling.2017; 27(1): 37.     CrossRef
  • Incidence of and Risk Factors for Free Bowel Perforation in Patients with Crohn’s Disease
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    Digestive Diseases and Sciences.2017; 62(6): 1607.     CrossRef
  • Crohn’s disease presenting as gastric outlet obstruction: a therapeutic challenge?
    Faisal Inayat, Waqas Ullah, Qulsoom Hussain, Khurram Shafique
    BMJ Case Reports.2017; : bcr-2016-218181.     CrossRef
  • Genetic Influences on the Development of Fibrosis in Crohn’s Disease
    Bram Verstockt, Isabelle Cleynen
    Frontiers in Medicine.2016;[Epub]     CrossRef
  • Crohn's Disease: Specific Concerns in the Elderly
    Wei-Chen Lin, Ming-Jen Chen, Cheng-Hsin Chu, Tsang-En Wang, Horng-Yuan Wang, Shou-Chuan Shih, Chen-Wang Chang
    International Journal of Gerontology.2016; 10(3): 126.     CrossRef
  • Structural and molecular features of intestinal strictures in rats with Crohn's-like disease
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    World Journal of Gastroenterology.2016; 22(22): 5154.     CrossRef
  • Disease Phenotype, Activity and Clinical Course Prediction Based on C-Reactive Protein Levels at Diagnosis in Patients with Crohn’s Disease: Results from the CONNECT Study
    Jee Hye Kwon, Jong Pil Im, Byong Duk Ye, Jae Hee Cheon, Hyun Joo Jang, Kang Moon Lee, You Sun Kim, Sang Wook Kim, Young Ho Kim, Geun Am Song, Dong Soo Han, Won Ho Kim, Joo Sung Kim
    Gut and Liver.2016; 10(4): 595.     CrossRef
  • Small Bowel Stricture Mimicking Megacolon in a Patient with Crohn's Disease
    Samuel Raimundo Fernandes, Luís Araújo Correia, José Velosa
    GE Portuguese Journal of Gastroenterology.2016; 23(6): 319.     CrossRef
  • Factors Associated with Anxiety and Depression in Korean Patients with Inactive Inflammatory Bowel Disease
    Min Chul Kim, Yoon Suk Jung, Young Seok Song, Jung In Lee, Jung Ho Park, Chong Il Sohn, Kyu Yong Choi, Dong Il Park
    Gut and Liver.2016;[Epub]     CrossRef
  • Disease monitoring in inflammatory bowel disease
    Shannon Chang
    World Journal of Gastroenterology.2015; 21(40): 11246.     CrossRef
  • Endoskopie in Diagnose, Therapie und Nachsorge
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    MMW - Fortschritte der Medizin.2015; 157(12): 63.     CrossRef
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    Visceral Medicine.2015; 31(4): 280.     CrossRef
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Computed Tomography Enterography and Magnetic Resonance Enterography in the Diagnosis of Crohn's Disease
Se Hyung Kim
Intest Res 2015;13(1):27-38.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.27
AbstractAbstract PDFPubReader

Imaging of the small bowel is complicated by its length and its overlapping loops. Recently, however, the development of crosssectional imaging techniques, such as computed tomography enterography (CTE) and magnetic resonance enterography (MRE) has shifted fundamental paradigms in the diagnosis and management of patients with suspected or known Crohn's disease (CD). CTE and MRE are noninvasive imaging tests that involve the use of intraluminal oral and intravenous contrast agents to evaluate the small bowel. Here, we review recent advances in each cross-sectional imaging modality, their advantages and disadvantages, and their diagnostic performances in the evaluation of small bowel lesions in CD.

Citations

Citations to this article as recorded by  
  • Analysis of the Accuracy of Magnetic Resonance Enterography for the Detection of Active Inflammation and Disease Activity in Patients With Crohn’s Disease: A Single-Center Experience in Najran, Saudi Arabia
    Qaed S Alhammami
    Cureus.2024;[Epub]     CrossRef
  • The Utility of Patency Capsule in Patients With Crohn’s Disease
    Tarek Odah, Christian Karime, Jana G. Hashash, Jami A. Kinnucan, Michael F. Picco, Francis A. Farraye
    Journal of Clinical Gastroenterology.2024;[Epub]     CrossRef
  • Improved comprehensive evaluation of Crohn’s disease activity by intestinal computed tomography enterography combined with endoscopy and biochemical indicators
    Yajun Liu, Feiyan Tian, Shuijiao Chen, jiuye Hu
    Arab Journal of Gastroenterology.2023; 24(1): 16.     CrossRef
  • Test Characteristics of Cross-sectional Imaging and Concordance With Endoscopy in Postoperative Crohn’s Disease
    Salam P. Bachour, Ravi S. Shah, Ruishen Lyu, Takahiro Nakamura, Michael Shen, Terry Li, Bari Dane, Edward L. Barnes, Florian Rieder, Benjamin Cohen, Taha Qazi, Bret Lashner, Jean Paul Achkar, Jessica Philpott, Stefan D. Holubar, Amy L. Lightner, Miguel Re
    Clinical Gastroenterology and Hepatology.2022; 20(10): 2327.     CrossRef
  • Clinical implication of radiologic complete remission on Crohn’s Disease: Compared with endoscopic remission
    Min Cheol Kim, Se Hyung Kim, Seong‑Joon Koh, Ji Hoon Park, Hyuk Yoon
    European Journal of Radiology.2022; 155: 110469.     CrossRef
  • Correlation between magnetic resonance enterography and ileo-colonoscopy for assessment of disease activity in terminal ileal Crohn’s disease
    Chandan Kakkar, Arshdeep Singh, Ramit Mahajan, Vandana Midha, Shriya Goyal, Vikram Narang, Kamini Gupta, Dharmatma Singh, Namita Bansal, Kavita Saggar, Ajit Sood
    Indian Journal of Gastroenterology.2022; 41(5): 465.     CrossRef
  • Prevalence and clinical significance of incidental extra-intestinal findings in MR enterography: experience of a single University Centre
    Filomenamila Lorusso, Mariabeatrice Principi, Pasquale Pedote, Pasquale Pignataro, Mariantonietta Francavilla, Angela Sardaro, Arnaldo Scardapane
    La radiologia medica.2021; 126(2): 181.     CrossRef
  • Crohn’s disease at radiological imaging: focus on techniques and intestinal tract
    Giuseppe Cicero, Silvio Mazziotti
    Intestinal Research.2021; 19(4): 365.     CrossRef
  • Computed Tomography Enterography Demonstrates Association to Histopathological Grading of Small Bowel Crohn’s Activity
    Husam H Mansour, Yasser S Alajerami, Ahmed A Najim, Khaled M Abushab
    Electronic Journal of General Medicine.2021; 18(6): em330.     CrossRef
  • Evaluating inflammatory activity in Crohn’s disease by cross-sectional imaging techniques
    Bruno Cunha Fialho Cantarelli, Rafael Santiago de Oliveira, Aldo Maurici Araújo Alves, Bruno Jucá Ribeiro, Fernanda Velloni, Giuseppe D’Ippolito
    Radiologia Brasileira.2020; 53(1): 38.     CrossRef
  • Association of Faecal Calprotectin Level and Combined Endoscopic and Radiological Healing in Patients With Crohn’s Disease Receiving Anti-tumour Necrosis Factor Therapy
    Soo Min Noh, Eun Hye Oh, Seong Ho Park, Jung Bok Lee, Jin Yong Kim, Jae Cheol Park, Jeongseok Kim, Nam Seok Ham, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Beyong Duk Ye
    Journal of Crohn's and Colitis.2020; 14(9): 1231.     CrossRef
  • Crohn's disease: A retrospective analysis between computed tomography enterography, colonoscopy, and histopathology
    C. Saade, L. Nasr, A. Sharara, K. Barada, A. Soweid, F. Murad, A. Tawil, D. Ghieh, K. Asmar, H. Tamim, N.J. Khoury
    Radiography.2019; 25(4): 349.     CrossRef
  • Value of dual-energy CT enterography in the analysis of pathological bowel segments in patients with Crohn's disease
    A.M. Villanueva Campos, G. Tardáguila de la Fuente, E. Utrera Pérez, C. Jurado Basildo, D. Mera Fernández, C. Martínez Rodríguez
    Radiología (English Edition).2018; 60(3): 223.     CrossRef
  • Valor de la enterografía por tomografía computarizada con doble energía en el análisis de segmentos intestinales patológicos en pacientes con enfermedad de Crohn
    A.M. Villanueva Campos, G. Tardáguila de la Fuente, E. Utrera Pérez, C. Jurado Basildo, D. Mera Fernández, C. Martínez Rodríguez
    Radiología.2018; 60(3): 223.     CrossRef
  • The effect of without using anisodamine during CT enterography on image quality, diagnostic performance and latent side effects
    Didi Wen, Jian Xu, Ying Liu, Rui An, Jian Li, Hongliang Zhao, Minwen Zheng
    Clinical Imaging.2018; 48: 106.     CrossRef
  • Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity
    Jingyun Cheng, Hui Xie, Hao Yang, Ke Wang, Guobin Xu, Guangyao Wu
    Gastroenterology Research and Practice.2018; 2018: 1.     CrossRef
  • Low-Dose Computed Tomography for the Optimization of Radiation Dose Exposure in Patients with Crohn’s Disease
    Richard G. Kavanagh, John O’Grady, Brian W. Carey, Patrick D. McLaughlin, Siobhan B. O’Neill, Michael M. Maher, Owen J. O’Connor
    Gastroenterology Research and Practice.2018; 2018: 1.     CrossRef
  • The Diagnostic Role of Magnetic Resonance Enterography as a Complementary Test to Colonoscopy in Active Crohn’s Disease
    Arvin Aryan, Zahra Azizi, Azam Teimouri, Nasser Ebrahimi Daryani, Najme Aletaha, Ali Jahanbakhsh, Mohammad Kazem Nouritaromlou, Forough Alborzi, Masoud Mami, Vahid Basirat, Sanam Javid Anbardan
    Middle East Journal of Digestive Diseases.2016; 8(2): 93.     CrossRef
  • Magnetic resonance enterography for the evaluation of the deep small intestine in Crohn's disease
    Kazuo Ohtsuka, Kento Takenaka, Yoshio Kitazume, Toshimitsu Fujii, Katsuyoshi Matsuoka, Maiko Kimura, Takashi Nagaishi, Mamoru Watanabe
    Intestinal Research.2016; 14(2): 120.     CrossRef
  • Assessment of Disease Activity in Small Bowel Crohn’s Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score
    Arnaldo Scardapane, Annalisa Ambrosi, Emanuela Salinaro, Maria Elisabetta Mancini, Mariabeatrice Principi, Alfredo Di Leo, Filomenamila Lorusso, Amato Antonio Stabile Ianora, Giuseppe Angelelli
    Gastroenterology Research and Practice.2015; 2015: 1.     CrossRef
  • Advances in imaging to allow personalized medicine in Crohn's disease
    Markus F Neurath
    Current Opinion in Pharmacology.2015; 23: 6.     CrossRef
  • 10,195 View
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  • 18 Web of Science
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Original Articles
Comparative Analysis of Gastrointestinal Microbiota Between Normal and Caudal-Related Homeobox 2 (Cdx2) Transgenic Mice
Hirotsugu Sakamoto, Takashi Asahara, Osamu Chonan, Norikatsu Yuki, Hiroyuki Mutoh, Shunji Hayashi, Hironori Yamamoto, Kentaro Sugano
Intest Res 2015;13(1):39-49.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.39
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

Caudal-related homeobox 2 (Cdx2) is expressed in the human intestinal metaplastic mucosa and induces intestinal metaplastic mucosa in the Cdx2 transgenic mouse stomach. Atrophic gastritis and intestinal metaplasia commonly lead to gastric achlorhydria, which predisposes the stomach to bacterial overgrowth. In the present study, we determined the differences in gut microbiota between normal and Cdx2 transgenic mice, using quantitative reverse transcription-polymerase chain reaction (qRT-PCR).

Methods

Twelve normal (control) and 12 Cdx2 transgenic mice were sacrificed, and the gastric, jejunal, ileac, cecal and colonic mucosa, and feces were collected. To quantitate bacterial microbiota, we used real-time qRTPCR with 16S rRNA gene-targeted, species-specific primers.

Results

The total numbers of bacteria in the gastric, jejunal, ileac, cecal, and colonic mucosa of the Cdx2 transgenic mice were significantly higher than those of the normal mice. The Bacteroides fragilis group and also Prevotella were not detected in the stomach of the normal mice, although they were detected in the Cdx2 transgenic mice. Moreover, the Clostridium coccoides group, Clostridium leptum subgroup, Bacteroides fragilis group, and Prevotella were not detected in the jejunum or ileum of the normal mice, although they were detected in the Cdx2 transgenic mice. The fecal microbiota of the normal mice was similar to that of the Cdx2 transgenic mice.

Conclusions

Our results showed the differences in composition of gut microbiota between normal and Cdx2 transgenic mice, which may be caused by the development of gastric achlorhydria and intestinal metaplasia in Cdx2 transgenic mice.

Citations

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  • Long non-coding RNAs as the pivotal regulators of epithelial mesenchymal transition through WNT/β-catenin signaling pathway in tumor cells
    Faezeh Tolue Ghasaban, Meysam Moghbeli
    Pathology - Research and Practice.2024; 263: 155683.     CrossRef
  • In vitro and in vivo evaluation of Lactobacillus strains and comparative genomic analysis of Lactobacillus plantarum CGMCC12436 reveal candidates of colonise-related genes
    Ying Shi, Jianxin Zhao, Lee Kellingray, Hao Zhang, Arjan Narbad, Qixiao Zhai, Wei Chen
    Food Research International.2019; 119: 813.     CrossRef
  • Down-regulated expression of LINC00518 prevents epithelial cell growth and metastasis in breast cancer through the inhibition of CDX2 methylation and the Wnt signaling pathway
    Hong-Bin Wang, Hong Wei, Jin-Song Wang, Lin Li, An-Yue Chen, Zhi-Gao Li
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2019; 1865(3): 708.     CrossRef
  • Transgenic and gene knockout mice in gastric cancer research
    Yannan Jiang, Yingyan Yu
    Oncotarget.2017; 8(2): 3696.     CrossRef
  • 5,712 View
  • 65 Download
  • 4 Web of Science
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Usefulness of the Cytomegalovirus Antigenemia Assay in Patients With Ulcerative Colitis
Jaeyoung Chun, Changhyun Lee, Ji-eun Kwon, Sung Wook Hwang, Sang Gyun Kim, Joo Sung Kim, Hyun Chae Jung, Jong Pil Im
Intest Res 2015;13(1):50-59.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.50
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

Patients with ulcerative colitis (UC) are at high risk for cytomegalovirus (CMV) reactivation. The usefulness of the CMV antigenemia assay in active UC patients has rarely been studied. We assessed whether the assay detects CMV colitis and predicts clinical outcomes in patients with UC.

Methods

We retrospectively reviewed the medical records of patients hospitalized for moderate-to-severe UC from 2003 to 2012. Positive CMV antigenemia was defined as ≥1 pp65-positive cell per 2×105 polymorphonuclear neutrophils. CMV colitis was defined as the presence of inclusion bodies and/or positive immunohistochemistry in the colonic mucosa. The primary outcome was steroid refractoriness, defined as the absence of clinical improvement after intravenous high-dose steroid administration.

Results

A total of 43 patients were enrolled. CMV antigenemia was detected in 12 (27.9%) patients. Positive CMV antigenemia was significantly associated with CMV colitis (P =0.001). The sensitivity and specificity of positive CMV antigenemia for diagnosing CMV colitis were 66.7% and 87.1%, respectively. Steroid refractoriness was found in 11 of 12 (91.7%) and 12 of 31 (38.7%) patients with positive and negative CMV antigenemia, respectively (P =0.002). The independent predictors for steroid refractoriness were positive CMV antigenemia (adjusted odds ratio [OR], 7.73; 95% confidence interval [CI], 1.22-49.19; P =0.030) and a shorter duration from the diagnosis of UC (adjusted OR, 0.99; 95% CI, 0.98-0.99; P =0.025).

Conclusions

The CMV antigenemia assay shows low sensitivity but high specificity for detecting CMV colitis and may predict steroid-refractory UC. Early rescue therapy might be considered in UC patients positive for CMV antigenemia.

Citations

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  • The association between antigenemia, histology with immunohistochemistry, and mucosal PCR in the diagnosis of ulcerative colitis with concomitant human cytomegalovirus infection
    Tsukasa Yamawaka, Hiroki Kitamoto, Masanori Nojima, Tomoe Kazama, Kohei Wagatsuma, Keisuke Ishigami, Shuji Yamamoto, Yusuke Honzawa, Minoru Matsuura, Hiroshi Seno, Hiroshi Nakase
    Journal of Gastroenterology.2023; 58(1): 44.     CrossRef
  • Predictive Factors of Cytomegalovirus Viremia during the Clinical Course of Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis: A Single Center Observational Study
    Makoto Harada, Ryohei Iwabuchi, Akinori Yamaguchi, Daiki Aomura, Yosuke Yamada, Kosuke Sonoda, Yutaka Kamimura, Koji Hashimoto, Yuji Kamijo
    Journal of Clinical Medicine.2023; 12(1): 351.     CrossRef
  • A quick guide to diagnosis and treatment of cytomegalovirus infection in the gut: current dilemmas
    Iļja Drjagunovs, Sniedze Laivacuma, Indra Zeltiņa, Aleksejs Derovs
    Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences..2022; 76(5-6): 585.     CrossRef
  • Iranian kidney transplant recipients with COVID‐19 infection: Clinical outcomes and cytomegalovirus coinfection
    Hamideh Molaei, Leila Khedmat, Eghlim Nemati, Zohreh Rostami, Seyed Hassan Saadat
    Transplant Infectious Disease.2021;[Epub]     CrossRef
  • Granulocyte and Monocyte Adsorptive Apheresis for Ulcerative Colitis in a Patient with Low Bone Mineral Density Due to Fanconi-Bickel Syndrome
    Makoto Tanaka, Mayuko Nakanishi, Hajime Miyazaki, Ryuichi Morita, Hiroki Eguchi, Yoshiya Takeda, Masanobu Katayama, Motoo Tanaka, Masamichi Bamba, Tadashi Shigematsu
    Internal Medicine.2021; 60(15): 2413.     CrossRef
  • Fulminant amebic colitis in a patient with concomitant cytomegalovirus infection after systemic steroid therapy: A case report
    Naoki Shijubou, Toshiyuki Sumi, Koki Kamada, Takeyuki Sawai, Yuichi Yamada, Tatsuru Ikeda, Hisashi Nakata, Yuji Mori, Hirofumi Chiba
    World Journal of Clinical Cases.2021; 9(15): 3726.     CrossRef
  • Risk Factors of Cytomegalovirus Reactivation in Ulcerative Colitis Patients: A Meta-Analysis
    Yafei Qin, Grace Wang, Dejun Kong, Guangming Li, Hongda Wang, Hong Qin, Hao Wang
    Diagnostics.2021; 11(11): 1952.     CrossRef
  • High mucosal cytomegalovirus DNA helps predict adverse short-term outcome in acute severe ulcerative colitis
    Saransh Jain, Divya Namdeo, Pabitra Sahu, Saurabh Kedia, Peush Sahni, Prasenjit Das, Raju Sharma, Vipin Gupta, Govind Makharia, Lalit Dar, Simon PL Travis, Vineet Ahuja
    Intestinal Research.2021; 19(4): 438.     CrossRef
  • Current Diagnostic and Therapeutic Approaches to Cytomegalovirus Infections in Ulcerative Colitis Patients Based on Clinical and Basic Research Data
    Yoshihiro Yokoyama, Tsukasa Yamakawa, Takehiro Hirano, Tomoe Kazama, Daisuke Hirayama, Kohei Wagatsuma, Hiroshi Nakase
    International Journal of Molecular Sciences.2020; 21(7): 2438.     CrossRef
  • Ulcerative Colitis and Cytomegalovirus Infection: From A to Z
    Fadi H Mourad, Jana G Hashash, Viraj C Kariyawasam, Rupert W Leong
    Journal of Crohn's and Colitis.2020; 14(8): 1162.     CrossRef
  • Cytomegalovirus and Inflammatory Bowel Diseases (IBD) with a Special Focus on the Link with Ulcerative Colitis (UC)
    Alexandre Jentzer, Pauline Veyrard, Xavier Roblin, Pierre Saint-Sardos, Nicolas Rochereau, Stéphane Paul, Thomas Bourlet, Bruno Pozzetto, Sylvie Pillet
    Microorganisms.2020; 8(7): 1078.     CrossRef
  • A Practical Review of Cytomegalovirus in Gastroenterology and Hepatology
    Ali Y. Fakhreddine, Catherine T. Frenette, Gauree G. Konijeti
    Gastroenterology Research and Practice.2019; 2019: 1.     CrossRef
  • Antiviral Treatment for Colonic Cytomegalovirus Infection in Ulcerative Colitis Patients Significantly Improved Their Surgery Free Survival
    Yinghong Wang, Pankaj Aggarwal, Xiuli Liu, Haiyan Lu, Lei Lian, Xianrui Wu, Shibin Guo, Nitin Aggarwal, Bret Lashner, Bo Shen
    Journal of Clinical Gastroenterology.2018; 52(4): e27.     CrossRef
  • Cytomegalovirus Enterocolitis and Cytomegalovirus Colitis Complicating Ulcerative Colitis
    Kiyotaka Okawa, Tetsuya Aoki, Wataru Ueda, Koji Sano, Hiroshi Ono, Syusuke Nakauchi
    Nippon Daicho Komonbyo Gakkai Zasshi.2018; 71(10): 470.     CrossRef
  • Approach to cytomegalovirus infections in patients with ulcerative colitis
    Sung Chul Park, Yoon Mi Jeen, Yoon Tae Jeen
    The Korean Journal of Internal Medicine.2017; 32(3): 383.     CrossRef
  • Cytomegalovirus and ulcerative colitis: Place of antiviral therapy
    Sylvie Pillet
    World Journal of Gastroenterology.2016; 22(6): 2030.     CrossRef
  • Targeting cytomegalovirus during ulcerative colitis flare-ups
    Hiroshi Nakase, Kei Onodera
    Expert Review of Gastroenterology & Hepatology.2016; 10(10): 1119.     CrossRef
  • Risk Factors and Clinical Outcomes Associated with Cytomegalovirus Colitis in Patients with Acute Severe Ulcerative Colitis
    Ho-Su Lee, Sang Hyoung Park, Sung-Han Kim, Jihun Kim, Jene Choi, Hyo Jeong Lee, Wan Soo Kim, Jeong-Mi Lee, Min Seob Kwak, Sung Wook Hwang, Dong-Hoon Yang, Kyung-Jo Kim, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Yong Sik Yoon, Chang Sik Yu, Jin-Ho Ki
    Inflammatory Bowel Diseases.2016; 22(4): 912.     CrossRef
  • When is an Assay of Cytomegalovirus Antigenemia Useful in Detecting Cytomegalovirus Colitis?
    Kyeong Ok Kim
    Intestinal Research.2015; 13(2): 182.     CrossRef
  • A Clinical Significance of Assessing Cytomegalovirus Infection Status in Patients With Ulcerative Colitis
    Sooyun Chang, Jae Hee Cheon
    Intestinal Research.2015; 13(1): 2.     CrossRef
  • Author's Reply
    Jaeyoung Chun, Jong Pil Im
    Intestinal Research.2015; 13(2): 184.     CrossRef
  • Evaluation of a multiplex PCR assay for detection of cytomegalovirus in stool samples from patients with ulcerative colitis
    Saifun Nahar
    World Journal of Gastroenterology.2015; 21(44): 12667.     CrossRef
  • 5,550 View
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Old Age at Diagnosis Is Associated With Favorable Outcomes in Korean Patients With Inflammatory Bowel Disease
Jae Hyuk Choi, Eun Soo Kim, Kwang Bum Cho, Kyung Sik Park, Yoo Jin Lee, Sang Min Lee, Yu Jin Kang, Byung Ik Jang, Kyeong Ok Kim
Intest Res 2015;13(1):60-67.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.60
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

Despite the rising incidence and prevalence of inflammatory bowel disease (IBD) in Asian populations, data regarding clinical characteristics of patients in Asia based on age at diagnosis are relatively sparse. The aim of this study was to compare clinical characteristics based on the age at diagnosis according to the Montreal Classification in Korean IBD patients.

Methods

We recruited consecutive patients with IBD at two tertiary hospitals and retrospectively reviewed their medical information. Patients were divided into three groups according to their age at diagnosis: youth (<17 years), young adult (17-40 years), and middle-old (>40 years). The main clinical characteristics for comparison were the achievement of a remission state at the last follow-up visit, cumulative rate of surgery, and cumulative use of immunomodulators and tumor necrosis factor-α (TNFα) blockers during the follow-up period.

Results

In total, 346 IBD patients were included (Crohn's disease [CD] 146 and ulcerative colitis 200; 36 youth, 202 young adult, and 113 middle-old). The middle-old group with CD was characterized by a predominance of uncomplicated behavior (P=0.013) and a lower frequency of perianal disease (P=0.009). The middle-old group was associated more with a less aggressive disease course than the younger group, as shown by more frequent remission (P=0.004), being less likely to undergo surgery (P<0.001), and lower cumulative use of immunomodulators and TNFα blockers (P<0.001).

Conclusions

Age at diagnosis according to the Montreal Classification is an important prognostic factor for Korean IBD patients.

Citations

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  • Impact of age at diagnosis on long‐term prognosis in patients with intestinal Behçet's disease
    Ji Young Chang, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jae Hee Cheon, Jihye Park
    Journal of Gastroenterology and Hepatology.2024; 39(3): 519.     CrossRef
  • Peripheral blood neutrophil-to-lymphocyte ratio in inflammatory bowel disease and disease activity: A meta-analysis
    Wei Fu, Hu Fu, Weixia Ye, Yinsuo Han, Xianqiang Liu, Sirui Zhu, Hongmin Li, Rong Tang, Qin Wang
    International Immunopharmacology.2021; 101: 108235.     CrossRef
  • Earlier Anti-Tumor Necrosis Factor Therapy of Crohn’s Disease Correlates with Slower Progression of Bowel Damage
    Hinaben Panchal, Mathilde Wagner, Manjil Chatterji, Bachir Taouli, Russell McBride, Jeromy R. Patterson, Ryan Ungaro, Marla Dubinsky, Judy Cho, David B. Sachar
    Digestive Diseases and Sciences.2019; 64(11): 3274.     CrossRef
  • Characteristics and management of patients with inflammatory bowel disease between a secondary and tertiary hospitals: a propensity score analysis
    Ki Hwan Song, Eun Soo Kim, Yoo Jin Lee, Byung Ik Jang, Kyeong Ok Kim, Sang Gyu Kwak, Hyun Seok Lee
    Intestinal Research.2018; 16(2): 216.     CrossRef
  • Risk Factors for Vitamin D, Zinc, and Selenium Deficiencies in Korean Patients with Inflammatory Bowel Disease
    Yoo Min Han, Hyuk Yoon, Soo Lim, Mi-Kyung Sung, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, Joo Sung Kim
    Gut and Liver.2017; 11(3): 363.     CrossRef
  • Sampling Strategies for Three-Dimensional Spatial Community Structures in IBD Microbiota Research
    Shaocun Zhang, Xiaocang Cao, He Huang
    Frontiers in Cellular and Infection Microbiology.2017;[Epub]     CrossRef
  • Influence of age at diagnosis on the clinical characteristics of Crohn's disease in Korea: Results from the CONNECT study
    Sung Wook Hwang, Jee Hyun Kim, Jong Pil Im, Byong Duk Ye, Hoon Sup Koo, Kyu Chan Huh, Jae Hee Cheon, You Sun Kim, Young Ho Kim, Dong Soo Han, Won Ho Kim, Joo Sung Kim
    Journal of Gastroenterology and Hepatology.2017; 32(10): 1716.     CrossRef
  • Impact of inflammatory bowel disease on daily life: an online survey by the Korean Association for the Study of Intestinal Diseases
    Young Sun Kim, Sung-Ae Jung, Kang-Moon Lee, Soo Jung Park, Tae Oh Kim, Chang Hwan Choi, Hyun Gun Kim, Won Moon, Chang Mo Moon, Hye Kyoung Song, Soo-Young Na, Suk-Kyun Yang
    Intestinal Research.2017; 15(3): 338.     CrossRef
  • Clinical Efficacy of Beclomethasone Dipropionate in Korean Patients with Ulcerative Colitis
    Yoon Jee Lee, Jae Hee Cheon, Jae Hyun Kim, SunHo Yoo, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, Tae Il Kim, Won Ho Kim
    Yonsei Medical Journal.2017; 58(1): 144.     CrossRef
  • Prediction of low bone mineral density in patients with inflammatory bowel diseases
    Solvey Schüle, Jean‐Benoît Rossel, Diana Frey, Luc Biedermann, Michael Scharl, Jonas Zeitz, Natália Freitas‐Queiroz, Valérie Pittet, Stephan R Vavricka, Gerhard Rogler, Benjamin Misselwitz
    United European Gastroenterology Journal.2016; 4(5): 669.     CrossRef
  • Effect of mucosal healing (Mayo 0) on clinical relapse in patients with ulcerative colitis in clinical remission
    Jae Hyun Kim, Jae Hee Cheon, Yehyun Park, Hyun Jung Lee, Soo Jung Park, Tae Il Kim, Won Ho Kim
    Scandinavian Journal of Gastroenterology.2016; 51(9): 1069.     CrossRef
  • Patients with perianal Crohn's disease have poor disease outcomes after primary bowel resection
    Yoo Min Han, Ji Won Kim, Seong‐Joon Koh, Byeong Gwan Kim, Kook Lae Lee, Jong Pil Im, Joo Sung Kim, Hyun Chae Jung
    Journal of Gastroenterology and Hepatology.2016; 31(8): 1436.     CrossRef
  • Clinical features of Crohn's disease in Korean patients residing in Busan and Gyeongnam
    Eun Ji Lee, Tae Oh Kim, Geun Am Song, Jong hun Lee, Hyung Wook Kim, Sam Ryong Jee, Seun Ja Park, Hyun Jin Kim, Jong Ha Park
    Intestinal Research.2016; 14(1): 30.     CrossRef
  • The Positive Influences of Increasing Age at Diagnosis of Inflammatory Bowel Disease on Disease Prognostication in Asian Perspective
    Raja Affendi Raja Ali
    Intestinal Research.2015; 13(1): 4.     CrossRef
  • Continuous duodenal levodopa infusion in a patient with Crohn's disease and small bowel surgery — Case report
    Svetlana Tomic, Danijela Skelac, Dario Mick, Ivan Segec, Bojan Resan, Silva Butkovic Soldo
    Journal of the Neurological Sciences.2015; 358(1-2): 525.     CrossRef
  • 5,892 View
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  • 15 Web of Science
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Circulating Ghrelin Levels and Obestatin/Ghrelin Ratio as a Marker of Activity in Ulcerative Colitis
Ja Young Jung, Ji Bong Jeong, Ji Won Kim, Su Hwan Kim, Seong-Joon Koh, Byeong Gwan Kim, Kook Lae Lee
Intest Res 2015;13(1):68-73.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.68
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

Ghrelin levels are known to increase in patients with ulcerative colitis (UC), but serum obestatin levels in UC patients are not well elucidated. The aim of this study was to examine the relationship between serum ghrelin and obestatin levels and disease activity in UC patients.

Methods

The serum ghrelin and obestatin levels were measured in 21 UC patients (12 with active disease and 9 in remission) using enzyme-linked immunosorbent assay. The relationship between the circulating levels of these 2 hormones and disease activity was analyzed. The colonic mucosal mRNA expression of ghrelin and obestatin was measured by quantitative reverse transcription polymerase chain reaction.

Results

The mean serum ghrelin values were significantly higher in patients with active disease than in patients with remission (1370.6±404.3 vs. 783.5±235.3 pg/mL, P=0.001). Colonic mucosal mRNA expression of ghrelin was also significantly higher in patients with active disease than in patients in remission (0.805±0.214 vs. 0.481±0.356, P=0.018). However, the mean serum obestatin levels and colonic mucosal mRNA expression of obestatin were not significantly different between both groups. The circulating obestatin/ghrelin ratio was significantly lower in patients with active UC than in patients in remission (0.32±0.08 vs. 0.58±0.20, P=0.001).

Conclusions

The serum ghrelin levels and the obestatin/ghrelin ratio were related to the activity of UC, but serum obestatin was not related to activity of UC. The ghrelin levels and the obestatin/ghrelin ratio could serve as activity markers in patients with UC.

Citations

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  • Unveiling the Ghrelin and Obestatin Roles in Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis Assessing Their Pathogenic Implications and Biomarker Utility
    Amirmohammad Khalaji, Nastaran Babajani, Zahra Amirsardari, Behrad Saeedian, Soheil Peiman, Nathan A Berger, Amir Hossein Behnoush
    Inflammatory Bowel Diseases.2024; 30(4): 629.     CrossRef
  • Effects of Spirulina supplementation in patients with ulcerative colitis: a double-blind, placebo-controlled randomized trial
    Sajjad Moradi, Reza Bagheri, Parsa Amirian, Mahsa Zarpoosh, Neda Cheraghloo, Alexei Wong, Mehdi Zobeiri, Mohammad Hassan Entezari
    BMC Complementary Medicine and Therapies.2024;[Epub]     CrossRef
  • “Sibling” battle or harmony: crosstalk between nesfatin-1 and ghrelin
    Xi Chen, Jing Dong, Qian Jiao, Xixun Du, Mingxia Bi, Hong Jiang
    Cellular and Molecular Life Sciences.2022;[Epub]     CrossRef
  • Role of the Ghrelin System in Colitis and Hepatitis as Risk Factors for Inflammatory-Related Cancers
    Aldona Kasprzak, Agnieszka Adamek
    International Journal of Molecular Sciences.2022; 23(19): 11188.     CrossRef
  • Correlation between the tissue ghrelin presence, disease activity and laboratory parameters in ulcerative colitis patients; immunohistochemical study
    Memduh Sahin, Kivilcim Eren Erdogan, Emine Tekingündüz, Gernot Zissel
    PLOS ONE.2022; 17(11): e0276065.     CrossRef
  • l-Glutamine and Physical Exercise Prevent Intestinal Inflammation and Oxidative Stress Without Improving Gastric Dysmotility in Rats with Ulcerative Colitis
    Raisa de Oliveira Santos, Geovane da Silva Cardoso, Lara da Costa Lima, Mickael Laudrup de Sousa Cavalcante, Mariana Sousa Silva, Ana Karolina Martins Cavalcante, Juliana Soares Severo, Francisca Beatriz de Melo Sousa, Gabriella Pacheco, Even Herlany Pere
    Inflammation.2021; 44(2): 617.     CrossRef
  • Obestatin and Its Fragments: A New Approach to the Regulation of Body Weight under Normal and Pathological Conditions
    A. V. Graf, E. E. Khirazova, M. V. Maslova, N. A. Sokolova
    Moscow University Biological Sciences Bulletin.2020; 75(2): 50.     CrossRef
  • Ghrelin and gastrointestinal wound healing. A new perspective for colorectal surgery
    Humberto Fenner Lyra Junior, Igor Kunze Rodrigues, Leonardo de Lucca Schiavon, Armando José D`Acâmpora
    Acta Cirurgica Brasileira.2018; 33(3): 282.     CrossRef
  • TNF-α inhibits SCF, ghrelin, and substance P expressions through the NF-κB pathway activation in interstitial cells of Cajal
    Keyu Ren, Chunming Yong, Hao Yuan, Bin Cao, Kun Zhao, Jin Wang
    Brazilian Journal of Medical and Biological Research.2018;[Epub]     CrossRef
  • Biochemical properties and biological actions of obestatin and its relevence in type 2 diabetes
    Brian D. Green, David J. Grieve
    Peptides.2018; 100: 249.     CrossRef
  • Treatment with Obestatin—A Ghrelin Gene-Encoded Peptide—Reduces the Severity of Experimental Colitis Evoked by Trinitrobenzene Sulfonic Acid
    Katarzyna Konarska, Jakub Cieszkowski, Zygmunt Warzecha, Piotr Ceranowicz, Anna Chmura, Beata Kuśnierz-Cabala, Krystyna Gałązka, Paweł Kowalczyk, Andrzej Miskiewicz, Thomas Jan Konturek, Michał Pędziwiatr, Artur Dembiński
    International Journal of Molecular Sciences.2018; 19(6): 1643.     CrossRef
  • Serum Adipocytokine Levels as Surrogate Markers for Disease Activity of Crohn’s Disease
    Su Hwan Kim, Seung Hyeon Jang, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, You Sun Kim, Dong Soo Han, Joo Sung Kim
    The American Journal of the Medical Sciences.2017; 353(5): 439.     CrossRef
  • Function of obestatin in the digestive system
    Yue-Xian Xing, Liu Yang, Hong-Yu Kuang, Xin-Yuan Gao, Hao-Ling Liu
    Nutrition.2017; 34: 21.     CrossRef
  • NF-kappa B activation correlates with disease phenotype in Crohn’s disease
    Yoo Min Han, Jaemoon Koh, Ji Won Kim, Changhyun Lee, Seong-Joon Koh, ByeongGwan Kim, Kook Lae Lee, Jong Pil Im, Joo Sung Kim, Gernot Sellge
    PLOS ONE.2017; 12(7): e0182071.     CrossRef
  • The obestatin/ghrelin ratio and ghrelin genetics in adult celiac patients before and after a gluten-free diet, in irritable bowel syndrome patients and healthy individuals
    Francesco Russo, Guglielmina Chimienti, Michele Linsalata, Caterina Clemente, Antonella Orlando, Giuseppe Riezzo
    European Journal of Gastroenterology & Hepatology.2017; 29(2): 160.     CrossRef
  • Plasma ghrelin level and plasma ghrelin/obestatin ratio are related to intestinal metaplasia in elderly patients with functional dyspepsia
    Su Hwan Kim, Ji Won Kim, Junsu Byun, Ji Bong Jeong, Byeong Gwan Kim, Kook Lae Lee, Zane B Andrews
    PLOS ONE.2017; 12(4): e0175231.     CrossRef
  • Obestatin as a key regulator of metabolism and cardiovascular function with emerging therapeutic potential for diabetes
    Elaine Cowan, Kerry J Burch, Brian D Green, David J Grieve
    British Journal of Pharmacology.2016; 173(14): 2165.     CrossRef
  • Obestatin Accelerates the Healing of Acetic Acid‐Induced Colitis in Rats
    Aleksandra Matuszyk, Piotr Ceranowicz, Zygmunt Warzecha, Jakub Cieszkowski, Joanna Bonior, Jolanta Jaworek, Beata Kuśnierz-Cabala, Peter Konturek, Tadeusz Ambroży, Artur Dembiński, Tanea T. Reed
    Oxidative Medicine and Cellular Longevity.2016;[Epub]     CrossRef
  • Ghrelin receptor modulates T helper cells during intestinal inflammation
    M. Di Giovangiulio, N. Stakenborg, G. Bosmans, E. Meroni, G. Farro, P. J. Gomez‐Pinilla, I. Depoortere, G. E. Boeckxstaens, G. Matteoli
    Neurogastroenterology & Motility.2015; 27(11): 1542.     CrossRef
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Alcohol Drinking Increased the Risk of Advanced Colorectal Adenomas
Yoon Kyung Song, Young Sook Park, Choon Sik Seon, Hye Jin Lim, Byung Kwan Son, Sang Bong Ahn, Young Kwan Jo, Seong Hwan Kim, Yun Ju Jo, Ji Hyun Lee, Seung Chan Kim
Intest Res 2015;13(1):74-79.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.74
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

Age, sex, gene and life style are modulating risks for colon cancer. Although alcohol intake may impact on colorectal adenoma, clear association has not been established yet. We aimed to investigate effects of alcohol consumption on the characteristics of colorectal adenoma.

Methods

Patients who underwent colonoscopic polypectomy of colorectal adenoma in the department of gastroenterology of Eulji hospital through 2005 to 2012, having both blood tests and ultrasound or abdominal CT examination were enrolled. The alcohol drinking patients were subdivided into normal or abnormal laboratory group, and alcoholic liver diseases group.

Results

212 patients with colorectal adenoma were analyzed; advanced adenoma and multiple adenoma were found in 68 (32.0%) and 79 (37.2%) patients. When compared to the nondrinker group (120/212 patients), the alcohol drinker group (92/212 patients) represented significantly high odds ratios (ORs) for advanced adenoma (OR, 2.697; P=0.002), and multiple adenoma (OR, 1.929; P=0.039). Among alcohol drinker (92 patients), the ORs of advanced adenoma were 6.407 (P=0.003) in alcoholic liver diseases group (17 patients), 3.711 (P=0.002) in the alcohol drinker with abnormal lab (24 patients), and 2.184 (P=0.034), in the alcohol drinker with normal lab (51 patients) compared to nondrinker group.

Conclusions

This study showed that alcohol drinking may influence on the development of advanced colorectal adenoma and multiplicity. Especially in the group with alcoholic liver diseases and with abnormal lab presented significantly higher ORs of advanced adenoma.

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  • Association between severe hepatic steatosis examined by Fibroscan and the risk of high-risk colorectal neoplasia
    Kwang Woo Kim, Hyoun Woo Kang, Hosun Yoo, Yukyung Jun, Hyun Jung Lee, Jong Pil Im, Ji Won Kim, Joo Sung Kim, Seong-Joon Koh, Yong Jin Jung, Atsushi Hosui
    PLOS ONE.2022; 17(12): e0279242.     CrossRef
  • Value of combined detection of IFOBT, tumor markers, and inflammatory markers in predicting occurrence of advanced colorectal adenoma
    Xu Wang, Jing-Yu Zhang, Zhong-Qing Zheng, Tao Wang, Mei-Yu Piao, Heng Liu, Jing Liu, Wen-Tian Liu
    World Chinese Journal of Digestology.2021; 29(7): 347.     CrossRef
  • Prevalence of Colorectal Polyps Based on Cardiorespiratory Fitness, Muscle Strength, Health Behavior, and Abdominal Obesity in Asymptomatic Elderly
    Shiyu Zhang, Junyong Zhang, Yonghwan Kim, Wangyang Zhang
    Healthcare.2021; 9(10): 1400.     CrossRef
  • Associations of Novel Dietary and Lifestyle Inflammation Scores With Incident Colorectal Cancer in the NIH-AARP Diet and Health Study
    Doratha A Byrd, Suzanne E Judd, W Dana Flanders, Terryl J Hartman, Veronika Fedirko, Tanya Agurs-Collins, Roberd M Bostick
    JNCI Cancer Spectrum.2020;[Epub]     CrossRef
  • Adenoma Characteristics and the Influence of Alcohol and Cigarette Consumption on the Development of Advanced Colorectal Adenomas
    Maja Čebohin, Senka Samardžić, Ksenija Marjanović, Martina Tot Vesić, Kristina Kralik, Andreja Bartulić, Dijana Hnatešen
    International Journal of Environmental Research and Public Health.2020; 17(22): 8296.     CrossRef
  • Associations of Novel Dietary and Lifestyle Inflammation Scores with Incident, Sporadic Colorectal Adenoma
    Doratha A. Byrd, Suzanne Judd, W. Dana Flanders, Terryl J. Hartman, Veronika Fedirko, Roberd M. Bostick
    Cancer Epidemiology, Biomarkers & Prevention.2020; 29(11): 2300.     CrossRef
  • Age at menarche and risk of colorectal adenoma
    Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
    The Korean Journal of Internal Medicine.2019; 34(5): 998.     CrossRef
  • Interplay of Liver Disease and Gut Microbiota in the Development of Colorectal Neoplasia
    Michael W. Gleeson
    Current Treatment Options in Gastroenterology.2019; 17(3): 378.     CrossRef
  • Gallbladder stones and gallbladder polyps associated with increased risk of colorectal adenoma in men
    Yen‐Ling Liu, Jin‐Shang Wu, Yi‐Ching Yang, Feng‐Hwa Lu, Chih‐Ting Lee, Wan‐Ju Lin, Chih‐Jen Chang
    Journal of Gastroenterology and Hepatology.2018; 33(4): 800.     CrossRef
  • The fecal immunochemical test has high accuracy for detecting advanced colorectal neoplasia before age 50
    Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
    Digestive and Liver Disease.2017; 49(5): 557.     CrossRef
  • Risk Factors for False Fecal Immunochemical Test Results in Colorectal Cancer Screening
    Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
    Journal of Clinical Gastroenterology.2017; 51(2): 151.     CrossRef
  • Sarcopenia is associated with an increased risk of advanced colorectal neoplasia
    Youn Su Park, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Jae Kyung Lee, Joo Sung Kim, Seong-Joon Koh
    International Journal of Colorectal Disease.2017; 32(4): 557.     CrossRef
  • Alcoholic Liver Disease Is Associated with an Increased Risk of Gastric Cancer
    Tae Hoon Ha, Byeong Gwan Kim, Donghyong Jeong, Sohee Oh, Won Kim, Yong Jin Jung, Dong Won Ahn, Ji Bong Jeong, Ji Won Kim, Kook Lae Lee, Seong-Joon Koh
    Digestive Diseases and Sciences.2017; 62(1): 273.     CrossRef
  • Metformin therapy and the risk of colorectal adenoma in patients with type 2 diabetes: A meta-analysis
    Yi-Chao Hou, Qiang Hu, Jiao Huang, Jing-Yuan Fang, Hua Xiong
    Oncotarget.2017; 8(5): 8843.     CrossRef
  • Statin use and the risk of colorectal adenoma: A meta‐analysis
    Yoon Suk Jung, Chan Hyuk Park, Chang Soo Eun, Dong Il Park, Dong Soo Han
    Journal of Gastroenterology and Hepatology.2016; 31(11): 1823.     CrossRef
  • Weight Change and Obesity Are Associated with a Risk of Adenoma Recurrence
    Yoon Suk Jung, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi
    Digestive Diseases and Sciences.2016; 61(9): 2694.     CrossRef
  • Metabolic syndrome is a risk factor for adenoma occurrence at surveillance colonoscopy
    Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
    Medicine.2016; 95(32): e4454.     CrossRef
  • Characteristics of and risk factors for colorectal neoplasms in young adults in a screening population
    Seung Eun Lee, Hee Bum Jo, Won Gun Kwack, Yun Jin Jeong, Yeo-Jin Yoon, Hyoun Woo Kang
    World Journal of Gastroenterology.2016; 22(10): 2981.     CrossRef
  • Does Low Threshold Value Use Improve Proximal Neoplasia Detection by Fecal Immunochemical Test?
    Nam Hee Kim, Hyo-Joon Yang, Soo-Kyung Park, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
    Digestive Diseases and Sciences.2016; 61(9): 2685.     CrossRef
  • Associations between amount of smoking and alcohol intake and risk of colorectal neoplasm
    Yoon Suk Jung, Hwanseok Jung, Kyung Eun Yun, Seungho Ryu, Yoosoo Chang, Dong Il Park, Kyuyong Choi
    Journal of Gastroenterology and Hepatology.2016; 31(4): 788.     CrossRef
  • Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?
    Martin Floer, Tobias Meister
    Digestion.2016; 93(3): 202.     CrossRef
  • Risk Factors for Colorectal Cancer in Thailand
    Kirati Poomphakwaen, Supannee Promthet, Krittika Suwanrungruang, Siriporn Kamsa-ard, Surapon Wiangnon
    Asian Pacific Journal of Cancer Prevention.2015; 16(14): 6105.     CrossRef
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Case Reports
Refractory Clostridium difficile Infection Cured With Fecal Microbiota Transplantation in Vancomycin-Resistant Enterococcus Colonized Patient
Mi-Ok Jang, Jun Hwan An, Sook-In Jung, Kyung-Hwa Park
Intest Res 2015;13(1):80-84.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.80
AbstractAbstract PDFPubReader

The rates and severity of Clostridium difficile infections, including pseudomembranous colitis, have increased markedly. However, there are few effective treatments for refractory or recurrent C. difficile infections and the outcomes are poor. Fecal microbiota transplantation is becoming increasingly accepted as an effective and safe intervention in patients with recurrent disease, likely due to the restoration of a disrupted microbiome. Cure rates of >90% are being consistently reported from multiple centers. We cured a case of severe refractory C. difficile infection with fecal microbiota transplantation in a patient colonized by vancomycin-resistant enterococcus.

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  • The potential utility of fecal (or intestinal) microbiota transplantation in controlling infectious diseases
    Rohma Ghani, Benjamin H. Mullish, Lauren A. Roberts, Frances J. Davies, Julian R. Marchesi
    Gut Microbes.2022;[Epub]     CrossRef
  • Make It Less difficile: Understanding Genetic Evolution and Global Spread of Clostridioides difficile
    Mariachiara Mengoli, Monica Barone, Marco Fabbrini, Federica D’Amico, Patrizia Brigidi, Silvia Turroni
    Genes.2022; 13(12): 2200.     CrossRef
  • Colonization Dynamics of Multidrug-Resistant Klebsiella pneumoniae Are Dictated by Microbiota-Cluster Group Behavior over Individual Antibiotic Susceptibility: A Metataxonomic Analysis
    János Juhász, Balázs Ligeti, Márió Gajdács, Nóra Makra, Eszter Ostorházi, Ferenc Balázs Farkas, Balázs Stercz, Ákos Tóth, Judit Domokos, Sándor Pongor, Dóra Szabó
    Antibiotics.2021; 10(3): 268.     CrossRef
  • Successful use of early, repeat fecal microbiota transplantation for initial treatment of severe, refractory Clostridioides difficile colitis
    Catherine M Cappetto
    American Journal of Health-System Pharmacy.2021; 78(15): 1374.     CrossRef
  • Fecal microbiota transplantation for antibiotic resistant bacteria decolonization
    Sophie Amrane, Jean-Christophe Lagier
    Human Microbiome Journal.2020; 16: 100071.     CrossRef
  • Faecal microbiota transplantation for the decolonization of antibiotic-resistant bacteria in the gut: a systematic review and meta-analysis
    V. Tavoukjian
    Journal of Hospital Infection.2019; 102(2): 174.     CrossRef
  • Fifty shades of graft: How to improve the efficacy of faecal microbiota transplantation for decolonization of antibiotic-resistant bacteria
    Benjamin Davido, Rui Batista, Aurélien Dinh, Pierre de Truchis, E.M. Terveer, Bruce Roberts, Ed J. Kuijper, Silvia Caballero
    International Journal of Antimicrobial Agents.2019; 53(5): 553.     CrossRef
  • RecurrentClostridium difficileInfection: Risk Factors, Treatment, and Prevention
    Jung Hoon Song, You Sun Kim
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  • Faecal microbiota transplantation for eradicating carriage of multidrug-resistant organisms: a systematic review
    S. Saha, R. Tariq, P.K. Tosh, D.S. Pardi, S. Khanna
    Clinical Microbiology and Infection.2019; 25(8): 958.     CrossRef
  • Gut Microbiota Modulation for Multidrug-Resistant Organism Decolonization: Present and Future Perspectives
    Livia Gargiullo, Federica Del Chierico, Patrizia D’Argenio, Lorenza Putignani
    Frontiers in Microbiology.2019;[Epub]     CrossRef
  • Efficacy and safety of fecal microbiota transplantation for decolonization of intestinal multidrug-resistant microorganism carriage: beyond Clostridioides difficile infection
    Young Kyung Yoon, Jin Woong Suh, Eun-Ji Kang, Jeong Yeon Kim
    Annals of Medicine.2019; 51(7-8): 379.     CrossRef
  • The Role of Fecal Microbiota Transplantation in Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape and Future Directions
    Michael H Woodworth, Mary K Hayden, Vincent B Young, Jennie H Kwon
    Open Forum Infectious Diseases.2019;[Epub]     CrossRef
  • Design and application of oral colon administration system
    Hao Cheng, Shiyu Huang, Gangliang Huang
    Journal of Enzyme Inhibition and Medicinal Chemistry.2019; 34(1): 1590.     CrossRef
  • The Intestinal Microbiota as a Reservoir and a Therapeutic Target to Fight Multi-Drug-Resistant Bacteria: A Narrative Review of the Literature
    Andrea Aira, Csaba Fehér, Elisa Rubio, Alex Soriano
    Infectious Diseases and Therapy.2019; 8(4): 469.     CrossRef
  • Intestinal microbiota and antibiotic resistance: Perspectives and solutions
    Climent Casals-Pascual, Andrea Vergara, Jordi Vila
    Human Microbiome Journal.2018; 9: 11.     CrossRef
  • The Use of Microbiome Restoration Therapeutics to Eliminate Intestinal Colonization With Multidrug-Resistant Organisms
    Srinivasa Nithin Gopalsamy, Michael H. Woodworth, Tiffany Wang, Cynthia T. Carpentieri, Nirja Mehta, Rachel J. Friedman-Moraco, Aneesh K. Mehta, Christian P. Larsen, Colleen S. Kraft
    The American Journal of the Medical Sciences.2018; 356(5): 433.     CrossRef
  • Mechanisms of antimicrobial resistance among hospital-associated pathogens
    Ayesha Khan, William R. Miller, Cesar A. Arias
    Expert Review of Anti-infective Therapy.2018; 16(4): 269.     CrossRef
  • The commensal microbiota exacerbate infectious colitis in stressor-exposed mice
    Jeffrey D. Galley, Nicola M. Parry, Brian M.M. Ahmer, James G. Fox, Michael T. Bailey
    Brain, Behavior, and Immunity.2017; 60: 44.     CrossRef
  • Microbial approaches for targeting antibiotic‐resistant bacteria
    Wing Fei Wong, Marina Santiago
    Microbial Biotechnology.2017; 10(5): 1047.     CrossRef
  • Clearance of Vancomycin-Resistant Enterococcus Concomitant With Administration of a Microbiota-Based Drug Targeted at Recurrent Clostridium difficile Infection
    Erik R. Dubberke, Kathleen M. Mullane, Dale N. Gerding, Christine H. Lee, Thomas J. Louie, Harriet Guthertz, Courtney Jones
    Open Forum Infectious Diseases.2016;[Epub]     CrossRef
  • Can Fecal Microbiota Transplantation (FMT) Eradicate Fecal Colonization With Vancomycin-Resistant Enterococci (VRE)?
    Kyung Mok Sohn, Shinhye Cheon, Yeon-Sook Kim
    Infection Control & Hospital Epidemiology.2016; 37(12): 1519.     CrossRef
  • Fecal Microbiota Transplantation: Current Applications, Effectiveness, and Future Perspectives
    Hyun Ho Choi, Young-Seok Cho
    Clinical Endoscopy.2016; 49(3): 257.     CrossRef
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  • 44 Download
  • 23 Web of Science
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Perianal Abscess and Proctitis by Klebsiella pneumoniae
Woo Shin Jeong, Sung Youn Choi, Eun Haeng Jeong, Ki Bae Bang, Seung Sik Park, Dae Sung Lee, Dong Il Park, Yoon Suk Jung
Intest Res 2015;13(1):85-89.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.85
AbstractAbstract PDFPubReader

Klebsiella pneumoniae (K. pneumoniae) can at times cause invasive infections, especially in patients with diabetes mellitus and a history of alcohol abuse. A 61-year-old man with diabetes mellitus and a history of alcohol abuse presented with abdominal and anal pain for two weeks. After admission, he underwent sigmoidoscopy, which revealed multiple ulcerations with yellowish exudate in the rectum and sigmoid colon. The patient was treated with ciprofloxacin and metronidazole. After one week, follow up sigmoidoscopy was performed owing to sustained fever and diarrhea. The lesions were aggravated and seemed webbed in appearance because of damage to the rectal mucosa. Abdominal computed tomography and rectal magnetic resonance imaging were performed, and showed a perianal and perirectal abscess. The patient underwent laparoscopic sigmoid colostomy and perirectal abscess incision and drainage. Extended-spectrum beta-lactamase-producing K. pneumoniae was identified in pus culture. The antibiotics were switched to ertapenem. He improved after surgery and was discharged. K. pneumoniae can cause rapid invasive infection in patients with diabetes and a history of alcohol abuse. We report the first rare case of proctitis and perianal abscess caused by invasive K. pneumoniae infection.

Citations

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  • Microbiota in adult perianal abscess revealed by metagenomic next-generation sequencing
    Jian-Chen Hong, Jian-Sheng Chen, Zai-Jie Jiang, Zhi-Chuan Chen, Ning Ruan, Xiang-Ping Yao, Rosemary C. She
    Microbiology Spectrum.2024;[Epub]     CrossRef
  • An Unusual Case of Proctitis and Rectal Abscess due to Irritants byArtemisia asiaticaSmoke (Ssukjwahun)
    Seunghyup Kim, You Sun Kim, Seo Hyun Kim, Dong Hoon Lee, Se Jun Park, Seo Young Yun, Dae Young Kim, Jeonghun Lee, Jeong Seop Moon
    The Korean Journal of Gastroenterology.2016; 67(4): 212.     CrossRef
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  • 2 Web of Science
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Anaphylactic Shock Caused by Ingestion of Polyethylene Glycol
Sun Hee Lee, Jae Myung Cha, Joung Il Lee, Kwang Ro Joo, Hyun Phil Shin, Il Hyun Baek, Jung Won Jeon, Jun Uk Lim, Jung Lok Lee, Hyae Min Lee, Young-Hak Cho
Intest Res 2015;13(1):90-94.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.90
AbstractAbstract PDFPubReader

Colonoscopy is the current standard method for evaluation of the colon. The diagnostic accuracy and therapeutic safety of colonoscopy depend on the quality of colonic cleansing and preparation. Generally, all these preparations have been demonstrated to be safe for use in healthy individuals without significant comorbid conditions. Based on safety and efficacy concerns, polyethylene glycol (PEG) is most commonly utilized as a bowel preparation solution for colonoscopy. Adverse events in patients receiving PEG are mostly clinically non-significant. However, fatal adverse events rarely have been shown to occur in the few individuals who experience vomiting or aspiration. Anaphylactic shock associated with ingestion of PEG electrolyte solution is an extremely rare fatal complication, and reported mainly in Western countries. Here, we report the first case of anaphylactic shock following the ingestion of PEG solution in Korea.

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    Journal of Histochemistry & Cytochemistry.2024; 72(7): 419.     CrossRef
  • Anaphylatoxin Complement 5a in Pfizer BNT162b2-Induced Immediate-Type Vaccine Hypersensitivity Reactions
    Xin Rong Lim, Grace Yin Lai Chan, Justina Wei Lynn Tan, Carol Yee Leng Ng, Choon Guan Chua, Guat Bee Tan, Stephrene Seok Wei Chan, Kiat Hoe Ong, Ying Zhi Tan, Sarah Hui Zhen Tan, Claire Min Li Teo, Samuel Shang Ming Lee, Bernard Yu Hor Thong, Bernard Pui
    Vaccines.2023; 11(6): 1020.     CrossRef
  • Anaphylactic shock induced by polyethylene glycol after bowel preparation for the colorectal cancer surgery: A case report
    Go Woon Park, Nahyeon Park, Jung Cheol Kuk, Eung Jin Shin, Dae Ro Lim
    World Journal of Clinical Cases.2023; 11(23): 5589.     CrossRef
  • Neither iatrogenic nor hereditary cause: A rare case of anaphylaxis to low sorb tubing used for infusions
    Amber Gibson, Muhammad Usman Baig, Sana Mohiuddin, Wafik Zaky
    Pediatric Blood & Cancer.2021;[Epub]     CrossRef
  • Anaphylaxis associated with the mRNA COVID-19 vaccines: Approach to allergy investigation
    Viktorija Erdeljic Turk
    Clinical Immunology.2021; 227: 108748.     CrossRef
  • Coronavirus disease 2019 vaccines and relevant adverse reactions
    Eun Hee Chung
    Allergy, Asthma & Respiratory Disease.2021; 9(3): 124.     CrossRef
  • Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies
    Bing-Mae Chen, Tian-Lu Cheng, Steve R. Roffler
    ACS Nano.2021; 15(9): 14022.     CrossRef
  • Anaphylaxis due to macrogol in a laxative solution with a positive basophil activation test
    Nicola Giangrande, Jesús Miguel García-Menaya, Mariana Marcos-Fernández, Carmen Cámara-Hijón, Pedro Bobadilla-González
    Annals of Allergy, Asthma & Immunology.2019; 123(3): 302.     CrossRef
  • Anaphylaxis due to polyethylene glycol: A case report
    Tae-Se Kim, Dong-Chull Choi, Byung-Jae Lee
    Allergy, Asthma & Respiratory Disease.2018; 6(5): 274.     CrossRef
  • Hyponatremic Seizures After Polyethylene Glycol Bowel Preparation: The Elderly at Risk
    Arjun Saradna, Shyam Shankar, Parita Soni, Chetana Pendkar, Abhinav Saxena, Yizhak Kupfer, Stephan Kamholz
    American Journal of Therapeutics.2018; 25(6): e779.     CrossRef
  • Anaphylaxis During Intracardiac and Endovascular Implantations: A Multifactorial Problem Involving Kounis Syndrome
    Nicholas G. Kounis, Ioanna Koniari, George Soufras, Grigorios Tsigkas, George Hahalis
    Journal of Cardiothoracic and Vascular Anesthesia.2017; 31(3): 804.     CrossRef
  • “Bowel prep hyponatremia“ – a state of acute water intoxication facilitated by low dietary solute intake: case report and literature review
    Martin Windpessl, Christoph Schwarz, Manfred Wallner
    BMC Nephrology.2017;[Epub]     CrossRef
  • Immediate‐type hypersensitivity to polyethylene glycols: a review
    E. Wenande, L. H. Garvey
    Clinical & Experimental Allergy.2016; 46(7): 907.     CrossRef
  • Anaphylaxis to Polyethylene Glycol (Colyte®) in a Patient with Diverticulitis
    So-Hee Lee, Sun Hyuk Hwang, Jin Soo Park, Hae-Sim Park, Yoo Seob Shin
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  • Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer
    Thomas J. Povsic, Monica G. Lawrence, A. Michael Lincoff, Roxana Mehran, Christopher P. Rusconi, Steven L. Zelenkofske, Zhen Huang, Jeffrey Sailstad, Paul W. Armstrong, P. Gabriel Steg, Christoph Bode, Richard C. Becker, John H. Alexander, N. Franklin Adk
    Journal of Allergy and Clinical Immunology.2016; 138(6): 1712.     CrossRef
  • Polyethylene Glycol (PEG)-Induced Anaphylactic Reaction During Bowel Preparation
    David Gachoka
    ACG Case Reports Journal.2015; 2(1): 216.     CrossRef
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A Patient With Intermittent Abdominal Pain for Three Weeks
Hyun Seok Lee
Intest Res 2015;13(1):95-96.   Published online January 29, 2015
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Questions About Sedation Protocols for Double-Balloon Enteroscopy
Dong-Hoon Yang
Intest Res 2015;13(1):97-98.   Published online January 29, 2015
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    Seong Ran Jeon
    Intestinal Research.2015; 13(1): 99.     CrossRef
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Seong Ran Jeon
Intest Res 2015;13(1):99-100.   Published online January 29, 2015
DOI: https://doi.org/10.5217/ir.2015.13.1.99
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