Intestinal Research

Original Articles

Clinical features of Crohn's disease in Korean patients residing in Busan and Gyeongnam: Eun Ji Lee, Tae Oh Kim, Geun Am Song, Jong hun Lee, Hyung Wook Kim, Sam Ryong Jee, Seun Ja Park, Hyun Jin Kim, Jong Ha Park; Intest Res 2016;14(1):30-36. Published online January 26, 2016; DOI: https://doi.org/10.5217/ir.2016.14.1.30

Background/Aims

Crohn's disease (CD) is a chronic inflammatory bowel disease that presents with variable features and repeated disease aggravation. The incidence of CD is increasing in Korea. We evaluated the clinical features of CD in a study population in Busan and Gyeongnam, Korea.

Methods

A hospital-based analysis included 619 patients diagnosed with CD between March 1986 and February 2013 from seven tertiary care hospitals in Busan and Gyeongnam. Individual case records were reviewed with regard to age at diagnosis, sex, disease location, disease behavior, and medical and surgical treatments received during the follow-up period.

Results

The cumulative frequency of patients diagnosed with CD revealed a continued increase in the number of cases reported yearly. The male-to-female ratio was 2.5:1 and the median age at diagnosis was 24 years. At diagnosis, 114 (18.4%) had isolated small bowel disease, 144 (23.3%) had isolated colonic disease, and 358 patients (57.8%) presented with disease in the small bowel and colon. The number of patients presenting with stricturing or penetrating disease behavior was 291 (47%) at the final evaluation. In total, 111 (17.9%) patients underwent intestinal resections.

Conclusions

A continued increase in the number of patients diagnosed with CD was found in Busan and Gyeongnam as observed in other regions. We report results similar to that of other Korean studies in terms of sex distribution, age, and location of disease.

Citations

Citations to this article as recorded by

Association between inflammatory bowel disease and osteoporosis in European and East Asian populations: exploring causality, mediation by nutritional status, and shared genetic architecture
Jian Kang, Xize Wu, Yue Li, Shuangli Zhao, Shixuan Wang, Dongdong Yu
Frontiers in Immunology.2024;[Epub] CrossRef
Inflammatory bowel disease in Korea: epidemiology and pathophysiology
Jung Won Lee, Chang Soo Eun
The Korean Journal of Internal Medicine.2022; 37(5): 885. CrossRef
NF-kappa B activation correlates with disease phenotype in Crohn’s disease
Yoo Min Han, Jaemoon Koh, Ji Won Kim, Changhyun Lee, Seong-Joon Koh, ByeongGwan Kim, Kook Lae Lee, Jong Pil Im, Joo Sung Kim, Gernot Sellge
PLOS ONE.2017; 12(7): e0182071. CrossRef
Are there interregional differences in the epidemiology and clinical characteristics of Crohn's disease in the Asia-Pacific region?
Sinwon Lee, Byong Duk Ye
Intestinal Research.2016; 14(1): 2. CrossRef
Changing epidemiological trends of inflammatory bowel disease in Asia
Wee Khoon Ng, Sunny H. Wong, Siew C. Ng
Intestinal Research.2016; 14(2): 111. CrossRef

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5 Web of Science
5 Crossref

Comparison of the Efficacy and Tolerability between Same-day Picosulfate and Split-dose Polyethylene Glycol Bowel Preparation for Afternoon Colonoscopy: A Prospective, Randomized, Investigator-blinded Trial: Mi Seon Kang, Tae Oh Kim, Eun Hee Seo, Da Kyung Jung, Mo Se Kim, Nae Yun Heo, Jong Ha Park, Seung Ha Park, Young Soo Moon; Intest Res 2014;12(1):53-59. Published online January 28, 2014; DOI: https://doi.org/10.5217/ir.2014.12.1.53

Abstract PDF PubReader

Background/Aims

In the present study, we evaluated the efficacy and tolerability between same-day bowel preparation protocols using 2 sachets of Picosulfate and a 4 L split-dose polyethylene glycol (PEG) bowel preparation for afternoon colonoscopy.

Methods

The study had a single-center, prospective, randomized, and investigator-blinded, non-inferiority design. We evaluated bowel preparation quality according to the Ottawa scale, patient tolerability, compliance, incidence of adverse events, sleep quality, and polyp/adenoma detection rate.

Results

Among the 196 patients analyzed (mean age, 55.3 years; 50.3% men), 97 received the same-day regimen of 2 sachets of picosulfate (group A) and 99 received the 4 L split-dose PEG regimen (group B). The Ottawa score of the total colon was 4.05±1.56 in group A and 3.80±1.55 in group B (P=0.255). The proportion of patients having adequate bowel preparation in the same-day picosulfate group (61.5%) was slightly less than the 4 L PEG group (71.3%); however, the difference was not statistically significant (P=0.133). Tolerability of the group A regimen was superior to that of the group B regimen (P<0.000). The same-day picosulfate regimen was associated with fewer adverse events, such as abdominal bloating (P=0.037) and better sleep quality (P<0.000).

Conclusions

The same-day picosulfate regimen and the 4 L split-dose PEG regimen had similar efficacy in bowel preparation for afternoon colonoscopy. However, the same-day picosulfate regimen was easier to administer, produced fewer adverse events, and enabled better sleep quality.

Citations

Citations to this article as recorded by

Efficacy and safety of same‐day preparation with sodium picosulfate plus magnesium citrate on the day of colonoscopy for bowel preparation: Multicenter, single‐arm, open‐label study
Hitomi Hori, Nobuaki Ikezawa, Shinwa Tanaka, Chise Ueda, Mizuho Fujisawa, Shinya Hoki, Hiroshi Tanabe, Ryosuke Ishida, Norihiro Okamoto, Hiroshi Takayama, Haruka Miyazaki, Hiroya Sakaguchi, Masato Kinoshita, Hirofumi Abe, Tetsuya Yoshizaki, Makoto Ooi, Ma
Journal of Gastroenterology and Hepatology.2024; 39(10): 2151. CrossRef
Comparison Between Same-Day and Split-Dose Preparations with Sodium Picosulfate/Magnesium Citrate: A Randomized Noninferiority Study
Chen-Ta Yang, Hsuan-Yuan Huang, Hsu-Heng Yen, Chia-Wei Yang, Yang-Yuan Chen, Siou-Ping Huang
Digestive Diseases and Sciences.2022; 67(8): 3964. CrossRef
Efectividad y tolerabilidad de tres tipos de productos de preparación para colonoscopia
Luis Fernando Roldán Molina, Lina María Roldán Delfino, Sandra Milena León Ramírez, Edilberto Elías Nuñez Cabarcas, Hilda María Pérez Useche, Antonio José Restrepo Peláez, María Adelaida Saffón Abad, Julio Eduardo Zuleta Muñoz, Juan Nicolás Zuluaga Aguila
Revista colombiana de Gastroenterología.2021; 36(3): 334. CrossRef
A prospective randomized clinical study evaluating the efficacy and compliance of oral sulfate solution and 2-L ascorbic acid plus polyethylene glycol
Ki Hwan Kwon, Ji Ae Lee, Yun Jeong Lim, Beom Jae Lee, Moon Kyung Joo, Yu Ra Sim, Wonjae Choi, Taehyun Kim, Ji Yoon Kim, Ei Rie Cho, Yoon Tae Jeen, Jong-Jae Park
The Korean Journal of Internal Medicine.2020; 35(4): 873. CrossRef
A randomized controlled trial on comparison of colon cleansing for colonoscopy bowel preparation using one-day or two-day regimen methods
Saleh Azadbakht, Morteza Azadbakht, Salehe Azadbakht, Alireza Esmaili, Parisa Rahmani
International Journal of Surgery Open.2020; 27: 140. CrossRef
Split-dose vs same-day bowel preparation for afternoon colonoscopies: A meta-analysis of randomized controlled trials
Nasim Parsa, Eric A Grisham, Courtney J Cockerell, Michelle L Matteson-Kome, Ramakrishna V Bysani, Sami Samiullah, Douglas L Nguyen, Veysel Tahan, Yezaz A Ghouri, Srinivas R Puli, Matthew L Bechtold
World Journal of Meta-Analysis.2020; 8(6): 461. CrossRef
Split-dose vs same-day bowel preparation for afternoon colonoscopies: A meta-analysis of randomized controlled trials
Nasim Parsa, Eric A Grisham, Courtney J Cockerell, Michelle L Matteson-Kome, Ramakrishna V Bysani, Sami Samiullah, Douglas L Nguyen, Veysel Tahan, Yezaz A Ghouri, Srinivas R Puli, Matthew L Bechtold
World Journal of Meta-Analysis.2020; 8(6): 462. CrossRef
Same-Day Regimen as an Alternative to Split Preparation for Colonoscopy: A Systematic Review with Meta-Analysis
Cristina Bucci, Fabiana Zingone, Pietro Schettino, Clelia Marmo, Riccardo Marmo
Gastroenterology Research and Practice.2019; 2019: 1. CrossRef
The Efficacy of Split-Dose Bowel Preparations for Polyp Detection: A Systematic Review and Meta-Analysis
Kathleen Zawaly, Colin Rumbolt, Ahmed M. Abou-Setta, Christine Neilson, Rasheda Rabbani, Ryan Zarychanski, Harminder Singh
American Journal of Gastroenterology.2019; 114(6): 884. CrossRef
Comparison of Bowel Cleansing Efficacy, Safety, Bowel Movement Kinetics, and Patient Tolerability of Same-Day and Split-Dose Bowel Preparation Using 4 L of Polyethylene Glycol: A Prospective Randomized Study
Myeongsook Seo, Tae-Geun Gweon, Cheal Wung Huh, Jeong Seon Ji, Hwang Choi
Diseases of the Colon & Rectum.2019; 62(12): 1518. CrossRef
Same-day Versus Split-dose Bowel Preparation Before Colonoscopy
Yuan-Lung Cheng, Kuang-Wei Huang, Wei-Chih Liao, Jiing-Chyuan Luo, Keng-Hsin Lan, Chien-Wei Su, Yuan-Jen Wang, Ming-Chih Hou
Journal of Clinical Gastroenterology.2018; 52(5): 392. CrossRef
Polyp detection rate may predict adenoma detection rate: a meta-analysis
Yaron Niv
European Journal of Gastroenterology & Hepatology.2018; 30(3): 247. CrossRef
Bowel Preparations Administered the Morning of Colonoscopy Provide Similar Efficacy to a Split Dose Regimen
Danny J. Avalos, Fernando J. Castro, Marc J. Zuckerman, Tara Keihanian, Andrew C. Berry, Benjamin Nutter, Daniel A. Sussman
Journal of Clinical Gastroenterology.2018; 52(10): 859. CrossRef
Sodium picosulphate or polyethylene glycol before elective colonoscopy in outpatients? A systematic review and meta-analysis
Rodrigo Silva de Paula Rocha, Igor Braga Ribeiro, Diogo Turiani Hourneaux de Moura, Wanderley Marques Bernardo, Maurício Kazuyoshi Minata, Flávio Hiroshi Ananias Morita, Júlio Cesar Martins Aquino, Elisa Ryoka Baba, Nelson Tomio Miyajima, Eduardo Guimarãe
World Journal of Gastrointestinal Endoscopy.2018; 10(12): 422. CrossRef
Low Volume Polyethylene Glycol (PEG) Plus Ascorbic Acid, a Valid Alternative to Standard PEG
Su Hwan Kim, Ji Won Kim
Gut and Liver.2016; 10(2): 160. CrossRef
Patient Descriptions of Rectal Effluents May Help to Predict the Quality of Bowel Preparation With Photographic Examples
Hoonsub So, Sun-Jin Boo, Hyungil Seo, Ho-Su Lee, Hyojeong Lee, Sang Hyoung Park, Kyung-Jo Kim, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Jin-Ho Kim, Seungbong Han, Dong-Hoon Yang
Intestinal Research.2015; 13(2): 153. CrossRef
Randomized controlled trial of low-volume bowel preparation agents for colonic bowel preparation: 2-L polyethylene glycol with ascorbic acid versus sodium picosulfate with magnesium citrate
Seong Ran Jeon, Hyun Gun Kim, Ji Seong Lee, Jin-Oh Kim, Tae Hee Lee, Jun-Hyung Cho, Yong Hun Kim, Joo Young Cho, Joon Seong Lee
International Journal of Colorectal Disease.2015; 30(2): 251. CrossRef
Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
Hong Jun Park, Myeong Hun Chae, Hyun-Soo Kim, Jae Woo Kim, Moon Young Kim, Soon Koo Baik, Sang Ok Kwon, Hee Man Kim, Kyong Joo Lee
Intestinal Research.2015; 13(4): 339. CrossRef
Bowel Preparation, the First Step for a Good Quality Colonoscopy
Ho-Su Lee, Jeong-Sik Byeon
Intestinal Research.2014; 12(1): 1. CrossRef

5,918 View
54 Download
16 Web of Science
19 Crossref

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