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Crohn’s disease at radiological imaging: focus on techniques and intestinal tract
Giuseppe Cicero, Silvio Mazziotti
Intest Res 2021;19(4):365-378.   Published online November 25, 2020
DOI: https://doi.org/10.5217/ir.2020.00097
AbstractAbstract PDFPubReaderePub
Over recent years, inflammatory bowel diseases have become an issue of increased attention in daily clinical practice, due to both a rising incidence and improved imaging capability in detection. In particular, the diagnosis of Crohn’s disease is based on clinical picture, laboratory tests and colonoscopy with biopsy. However, colonoscopic evaluation is limited to the mucosal layer. Thus, imaging modalities play a pivotal role in enriching the clinical picture, delivering information on intestinal and extraintestinal involvement. All the imaging modalities can be employed in evaluation of Crohn’s disease patients, each of them with specific strengths as well as limitations. In this wide selection, the choice of a proper diagnostic framework can be challenging for the clinician. Therefore, the aim of this work is to offer an overview of the different imaging techniques, with brief technical details and diagnostic potential related to each intestinal tract.

Citations

Citations to this article as recorded by  
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    G. Schmutz, D. Régent, H.M. Loi, Y. Ranchoup, E. Danse
    EMC - Gastro-entérologie.2025; 42(3): 1.     CrossRef
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    Caitlin Cassimatis, Peter O'Reilly, Amir Tavakoli Taba
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    Giuseppe Cicero, Silvio Mazziotti
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  • Portal hypertensive enteropathy: multimodality assessment through computed tomography and magnetic resonance enterography
    Giuseppe Cicero, Francesco Marcello Aricò, Anna Viola, Velio Ascenti, Silvio Mazziotti
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  • DWI ratios: New indexes for Crohn’s disease activity at magnetic resonance enterography?
    Giuseppe Cicero, Angela Alibrandi, Alfredo Blandino, Velio Ascenti, Walter Fries, Anna Viola, Silvio Mazziotti
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    Giuseppe Cicero, Giorgio Ascenti, Alfredo Blandino, Renato Trimarchi, Christian Booz, Thomas J. Vogl, Tommaso D’Angelo, Silvio Mazziotti
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  • 23 Web of Science
  • 30 Crossref
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Original Article
Thirty-day mortality after percutaneous gastrostomy by endoscopic versus radiologic placement: a systematic review and meta-analysis
Joo Hyun Lim, Seung Ho Choi, Changhyun Lee, Ji Yeon Seo, Hae Yeon Kang, Jong In Yang, Su Jin Chung, Joo Sung Kim
Intest Res 2016;14(4):333-342.   Published online October 17, 2016
DOI: https://doi.org/10.5217/ir.2016.14.4.333
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

A percutaneous gastrostomy can be placed either endoscopically (percutaneous endoscopic gastrostomy, PEG) or radiologically (radiologically-inserted gastrostomy, RIG). However, there is no consistent evidence of the safety and efficacy of PEG compared to RIG. Recently, 30-day mortality has become considered as the most important surrogate index for evaluating the safety and efficacy of percutaneous gastrostomy. The aim of this meta-analysis was to compare the 30-day mortality rates between PEG and RIG.

Methods

Major electronic databases (MEDLINE, Embase, Scopus, and Cochrane library) were queried for comparative studies on the two insertion techniques of gastrostomy among adults with swallowing disturbance. The primary outcome was the 30-day mortality rate after gastrostomy insertion. Forest and funnel plots were generated for outcomes using STATA version 14.0.

Results

Fifteen studies (n=2,183) met the inclusion criteria. PEG was associated with a lower risk of 30-day mortality after tube placement compared with RIG (odds ratio, 0.60; 95% confidence interval [CI], 0.38–0.94; P=0.026). The pooled prevalence of 30-day mortality of PEG was 5.5% (95% CI, 4.0%–6.9%) and that of RIG was 10.5% (95% CI, 6.8%–14.3%). No publication bias was noted.

Conclusions

The present meta-analysis demonstrated that PEG is associated with a lower probability of 30-day mortality compared to RIG, suggesting that PEG should be considered as the first choice for long-term enteral tube feeding. Further prospective randomized studies are needed to evaluate and compare the safety of these two different methods of gastrostomy.

Citations

Citations to this article as recorded by  
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