Intestinal Research

Review

Population-based screening colonoscopy in Korea: balancing benefits and limitations: Hyoung Il Choi, Jae Myung Cha; Received August 22, 2025 Accepted September 28, 2025 Published online January 2, 2026; DOI: https://doi.org/10.5217/ir.2025.00188 [Epub ahead of print]

Abstract PDF PubReader ePub: Population-based colonoscopy screening is considered one of the most effective strategies for reducing the incidence and mortality of colorectal cancer. Its major strength lies in its dual benefits: early detection of colorectal cancer and prevention via the removal of precancerous lesions. Colonoscopy has a high sensitivity and provides a full colonic evaluation in a single session, thereby reducing the need for frequent testing. However, this approach has notable limitations. Colonoscopy is an invasive procedure associated with rare but serious complications such as perforation and bleeding. Participation rates tend to be lower than those of noninvasive methods like fecal immunochemical tests. Additionally, implementing colonoscopy as a populationbased tool requires significant resources, including trained endoscopists, endoscopy facilities, and financial investments. The quality of colonoscopy may also vary depending on the operator’s skill and adherence to guidelines. Given these trade-offs, population-based colonoscopy screening must be carefully evaluated in terms of cost-effectiveness, feasibility, and public acceptance within each country’s healthcare system. Therefore, population-based colonoscopy screening should be approached with a balanced understanding of its benefits and limitations to ensure cost-effectiveness, feasibility, alignment with each country’s healthcare infrastructure, and integration with existing screening programs.

1,236 View
115 Download

Original Articles

Tumor

The impact of the COVID-19 pandemic on clinical practices related to colorectal cancer and colonoscopy in South Korea: a nationwide population-based study: Jin Young Yoon, Moon Hyung Lee, Min Seob Kwak, Jae Myung Cha; Intest Res 2025;23(1):85-95. Published online November 29, 2024; DOI: https://doi.org/10.5217/ir.2024.00066

Abstract PDF Supplementary Material PubReader ePub

Background/Aims
Despite of the coronavirus disease 2019 (COVID-19) pandemic, there is little data regarding its impact on colorectal cancer (CRC)-related clinical practice. This study aimed to assess the changes in its impact during the COVID-19 pandemic.
Methods
This was a retrospective national population-based study using the Health Insurance Review and Assessment database from January 2019 to December 2021. The number of patients in 2020 and 2021 was compared with those in 2019 for the diagnostic and therapeutic colonoscopy, CRC-related operation, and any treatment for CRC.
Results
The annual number of patients undergoing diagnostic colonoscopies decreased by 6.9% in 2020 but increased 8.1% in 2021, compared to those in 2019; number of patients undergoing therapeutic colonoscopies increased by 6.0% and 37.7% in 2020 and 2021, respectively; number of patients operated for CRC decreased by 4.2% in 2020 and increased by 2.3% in 2021. The number of patients treated for CRC decreased by 2.8% in 2020 and increased by 4.4% in 2021. Diagnostic and therapeutic colonoscopies and any CRC-related treatment decreased by 43.8%, 37.5%, and 11.3% in March 2020, during the first surge of COVID-19, but increased by 26.0%, 58.1%, and 9.5% in June 2021, respectively. CRC-related operations decreased by 24.1% in April 2020 and increased by 12.6% in August 2021.
Conclusions
Negative impact of the COVID-19 pandemic on clinical practices related to CRC completely recovered within second year. It could be considered for the development of an optimal strategy on CRC management in response to the pandemic-driven crisis.

Citations

Citations to this article as recorded by

Achievements and Future Directions of the National Colorectal Cancer Screening Program in Korea
Tae-Woo Kim, Soo-Young Na
The Korean Journal of Gastroenterology.2026; 86(2): 104. CrossRef
The impact of COVID-19 on clinical practices of colorectal cancer in South Korea
Kwang Woo Kim, Hyoun Woo Kang
Intestinal Research.2025; 23(1): 6. CrossRef

5,802 View
56 Download
2 Web of Science
2 Crossref

Colorectal neoplasia

The elderly population are more vulnerable for the management of colorectal cancer during the COVID-19 pandemic: a nationwide, population-based study: Hong Sun Kang, Seung Hoon Jeon, Su Bee Park, Jin Young Youn, Min Seob Kwak, Jae Myung Cha; Intest Res 2023;21(4):500-509. Published online August 29, 2023; DOI: https://doi.org/10.5217/ir.2023.00004

Abstract PDF Supplementary Material PubReader ePub

Background/Aims
The impact of coronavirus disease 2019 (COVID-19) on the management of colorectal cancer (CRC) may worse in elderly population, as almost all COVID-19 deaths occurred in the elderly patients. This study aimed to evaluate the impact of COVID-19 on CRC management in the elderly population.
Methods
The numbers of patients who underwent colonoscopy, who visited hospitals or operated for CRC in 2020 and 2021 (COVID-19 era) were compared with those in 2019, according to 3 age groups (≥70 years, 50–69 years, and ≤49 years), based on the nationwide, population-based database (2019–2021) in South Korea.
Results
The annual volumes of colonoscopy and hospital visits for CRC in 2020 were more significantly declined in the old age group than in the young age group (both P<0.001). In addition, the annual volume of patients operated for CRC numerically more declined in old age group than in young age group. During the first surge of COVID-19 (March and April 2020), old age patients showed statistically significant declines for the monthly number of colonoscopies (–46.5% vs. –39.3%, P<0.001), hospital visits (–15.4% vs. –7.9%, P<0.001), CRC operations (–33.8% vs. –0.7%, P<0.05), and colonoscopic polypectomies (–41.8% vs. –38.0%, P<0.001) than young age patients, compared with those of same months in 2019.
Conclusions
Elderly population are more vulnerable for the management of CRC during the COVID-19 pandemic. Therefore, the elderly population are more carefully cared for in the management of CRC during the next pandemic.

Citations

Citations to this article as recorded by

The impact of COVID-19 on clinical practices of colorectal cancer in South Korea
Kwang Woo Kim, Hyoun Woo Kang
Intestinal Research.2025; 23(1): 6. CrossRef
To overcome medical gap in screening and surveillance of colorectal cancer during the COVID-19 pandemic
Yoo Min Han
Intestinal Research.2023; 21(4): 418. CrossRef

6,076 View
205 Download
2 Web of Science
2 Crossref

Reviews

Endoscopy

Quality is the key for emerging issues of population-based colonoscopy screening: Jin Young Yoon, Jae Myung Cha, Yoon Tae Jeen; Intest Res 2018;16(1):48-54. Published online January 18, 2018; DOI: https://doi.org/10.5217/ir.2018.16.1.48

Abstract PDF PubReader ePub

Colonoscopy is currently regarded as the gold standard and preferred method of screening for colorectal cancer (CRC). However, the benefit of colonoscopy screening may be blunted by low participation rates in population-based screening programs. Harmful effects of population-based colonoscopy screening may include complications induced by colonoscopy itself and by sedation, psychosocial distress, potential over-diagnosis, and socioeconomic burden. In addition, harmful effects of colonoscopy may increase with age and comorbidities. As the risk of adverse events in population-based colonoscopy screening may offset the benefit, the adverse events should be managed and monitored. To adopt population-based colonoscopy screening, consensus on the risks and benefits should be developed, focusing on potential harm, patient preference, socioeconomic considerations, and quality improvement of colonoscopy, as well as efficacy for CRC prevention. As suboptimal colonoscopy quality is a major pitfall of population-based screening, adequate training and regulation of screening colonoscopists should be the first step in minimizing variations in quality. Gastroenterologists should promote quality improvement, auditing, and training for colonoscopy in a population-based screening program.

Citations

Citations to this article as recorded by

Mixed lesions in premalignant colorectal polyps
Toru Arano, Toshihiro Nishizawa, Hidenobu Watanabe, Mari Mizutani, Teppei Akimoto, Masaya Sano, Hirotoshi Ebinuma, Hidekazu Suzuki, Keisuke Hata, Osamu Toyoshima
Journal of Clinical Biochemistry and Nutrition.2026; 78(1): 83. CrossRef
Glycoproteomics of Gastrointestinal Cancers and Its Use in Clinical Diagnostics
Tomas Bertok, Andrea Pinkeova, Lenka Lorencova, Anna Datkova, Michal Hires, Eduard Jane, Jan Tkac
Journal of Proteome Research.2025; 24(6): 2584. CrossRef
Evaluation of the “Burgenland PREvention trial of colorectal cancer Disease with ImmunologiCal Testing” (B-PREDICT)—a population-based colorectal cancer screening program
Stefanie BREZINA, Gernot LEEB, Andreas BAIERL, Evelyn GRÄF, Monika HACKL, Philipp HOFER, Harald LANG, Michaela KLEIN, Karl MACH, Remy SCHWARZER, Wilhelm WLASSITS, Andreas PÜSPÖK, Andrea GSUR
BMC Gastroenterology.2024;[Epub] CrossRef
Strategies to improve screening colonoscopy quality for the prevention of colorectal cancer
Joo Hye Song, Eun Ran Kim
The Korean Journal of Internal Medicine.2024; 39(4): 547. CrossRef
The adult large bowel: describing environment morphology for effective biomedical device development
Joseph C Norton, James W Martin, Conchubhair Winters, Bruno Scaglioni, Keith L Obstein, Venkataraman Subramanian, Pietro Valdastri
Progress in Biomedical Engineering.2024; 6(3): 032003. CrossRef
Efficacy of colonoscopic re-examination across the entire colon: a randomized controlled trial
Dong Seok Lee, Jeong-Seon Ji, Tae-Geun Gweon, Myeongsook Seo, Hwang Choi
Surgical Endoscopy.2024; 38(11): 6711. CrossRef
Comment on " Positive fecal immunochemical test results are associated with non-colorectal cancer mortality"
Yong Eun Park
The Korean Journal of Internal Medicine.2023; 38(2): 264. CrossRef
Challenges and Suggestions in the Management of Stomach and Colorectal Cancer in Uzbekistan: The Third Report of the Uzbekistan–Korea Oncology Consortium
Chai Hong Rim, Won Jae Lee, Odiljon Akhmedov, Ulugbek Sabirov, Yakov Ten, Yakhyo Ziyayev, Mirzagaleb Tillyashaykhov, Jae Suk Rim
International Journal of Environmental Research and Public Health.2023; 20(8): 5477. CrossRef
Gastrointestinal Cancer Prevention Policies: A Qualitative Systematic Review and Meta-Synthesis
Neda Kabiri, Rahim Khodayari-zarnaq, Manouchehr Khoshbaten, Ali Janati
International Journal of Preventive Medicine.2022;[Epub] CrossRef
Quality indicators in colonoscopy: the chasm between ideal and reality
Su Bee Park, Jae Myung Cha
Clinical Endoscopy.2022; 55(3): 332. CrossRef
Effect of prophylactic clip application for the prevention of postpolypectomy bleeding of large pedunculated colonic polyps: a randomized controlled trial
Tae-Geun Gweon, Kang-Moon Lee, Seung-Woo Lee, Dae Bum Kim, Jeong-Seon Ji, Ji Min Lee, Woo Chul Chung, Chang-Nyol Paik, Hwang Choi
Gastrointestinal Endoscopy.2021; 94(1): 148. CrossRef
Comparison of adenoma detection by colonoscopy between polypectomy performed during both insertion and withdrawal versus during withdrawal only: a multicenter, randomized, controlled trial
Tae-Geun Gweon, Seung-Woo Lee, Jeong-Seon Ji, Jeong Rok Lee, Joon Sung Kim, Byung-Wook Kim, Hwang Choi
Surgical Endoscopy.2020; 34(12): 5461. CrossRef
Strategies to Increase the Participation Rate of Colorectal Cancer Screening
Yoon Suk Jung
Gut and Liver.2020; 14(3): 277. CrossRef
UEG Week 2018 Poster Presentations

United European Gastroenterology Journal.2018;[Epub] CrossRef

9,144 View
72 Download
13 Web of Science
14 Crossref

Would You Recommend Screening Colonoscopy for the Very Elderly?: Jae Myung Cha; Intest Res 2014;12(4):275-280. Published online October 27, 2014; DOI: https://doi.org/10.5217/ir.2014.12.4.275

Abstract PDF PubReader ePub

Life expectancy in Korea has increased, and the number of screening colonoscopies in the elderly has also dramatically increased. The net benefit of colonoscopy in the very elderly (≥80 years of age as defined by the World Health Organization) may be reduced because of the competing risk of mortality due to other diseases. Therefore, the decision to perform screening colonoscopy may be more complex in this age group. As the potential increase in life expectancy due to screening colonoscopy is significantly reduced in the very elderly, this procedure should be limited to those among the very elderly who have substantial life expectancies. Furthermore, considering the common major complications associated with colonoscopy, poor bowel preparation, and the possibility of incomplete colonoscopies in the very elderly, the performance of screening colonoscopy in the very elderly may not be an ideal recommendation. In terms of providing the greatest benefit to the most number of people, patients with the highest potential gain in terms of life expectancy, relative to the diagnostic yield, should be targeted for colonoscopy screening. This review addresses the unique considerations regarding screening colonoscopy in the very elderly and the individualized approach, which involves the weighing of the risks and benefits for each individual with consideration of their overall health status.

Citations

Citations to this article as recorded by

Linaclotide in combination with compound polyethylene glycol powder enhances bowel preparation for colonoscopy in patients aged over 60 years: a multi-center, endoscopist-blind, randomized controlled trial
Wenjing Sun, Lishi Zhao, Yamei Ran, Wenyan Zhao, Li Zhang, Juan Xiao, Yongmei Peng, Zhongxiao Zhang, Mei Dong, Shu Xiang, Kangqi Wu
Scandinavian Journal of Gastroenterology.2026; 61(1): 10. CrossRef
Association between colonoscopy and colorectal cancer occurrence and mortality in the older population: a population-based cohort study
Ji Young Lee, Jae Myung Cha, Jin Young Yoon, Min Seob Kwak, Hun Hee Lee
Endoscopy.2025; 57(05): 451. CrossRef
Efficacy and safety of 1 L polyethylene glycol plus ascorbic acid for bowel preparation in elderly: comparison with oral sulfate solution
Ki Young Lim, Kyeong Ok Kim, Eun Young Kim, Yoo Jin Lee, Byung Ik Jang, Sung Kook Kim, Chang Heon Yang
The Korean Journal of Internal Medicine.2023; 38(5): 651. CrossRef
Correlation between prescribing doctor attributes and intestinal cleanliness in colonoscopy: a study of 22522 patients
Haibin Zhou, Hayat Khizar, Xiaofeng Zhang, Jianfeng Yang
Annals of Medicine.2023;[Epub] CrossRef
Impact of an Abdominal Compression Bandage on the Completion of Colonoscopy for Obese Adults: A Prospective Randomized Controlled Trial
Ting-Ting Liu, Yi-Teng Meng, Feng Xiong, Cheng Wei, Su Luo, Sheng-Gang Zhan, Yang Song, Ying-Xue Li, Rui-Yue Shi, Jun Yao, Li-Sheng Wang, De-Feng Li, Xingshun Qi
Canadian Journal of Gastroenterology and Hepatology.2022; 2022: 1. CrossRef
Smartphone education improves embarrassment, bowel preparation, and satisfaction with care in patients receiving colonoscopy
Ming-Chu Wen, Kevin Kau, Sheng-Shiung Huang, Wen-Hsin Huang, Li-Yun Tsai, Tsung-Yu Tsai, Shiow-Luan Tsay
Medicine.2020; 99(46): e23102. CrossRef
Safety and Efficacy of Low-Volume Preparation in the Elderly: Oral Sulfate Solution on the Day before and Split-Dose Regimens (SEE SAFE) Study
Min Seob Kwak, Jae Myung Cha, Hyo-Joon Yang, Dong Il Park, Kyeong Ok Kim, Jun Lee, Jeong Eun Shin, Young-Eun Joo, Jongha Park, Jeong-Sik Byeon, Hyun Gun Kim
Gut and Liver.2019; 13(2): 176. CrossRef
Same-Day Single Dose of 2 Liter Polyethylene Glycol is Not Inferior to The Standard Bowel Preparation Regimen in Low-Risk Patients: A Randomized, Controlled Trial
Xiaoyu Kang, Lina Zhao, Zhiyong Zhu, Felix Leung, Limei Wang, Xiangping Wang, Hui Luo, Linhui Zhang, Tao Dong, Pingying Li, Zhangqin Chen, Gui Ren, Hui Jia, Xiaoyang Guo, Yanglin Pan, Xuegang Guo, Daiming Fan
American Journal of Gastroenterology.2018; 113(4): 601. CrossRef
Impact of patient audiovisual re-education via a smartphone on the quality of bowel preparation before colonoscopy: a single-blinded randomized study
Su Young Back, Hyun Gun Kim, Eu Mi Ahn, Suyeon Park, Seong Ran Jeon, Hee Hyuk Im, Jin-Oh Kim, Bong Min Ko, Joon Seong Lee, Tae Hee Lee, Jun-Hyung Cho
Gastrointestinal Endoscopy.2018; 87(3): 789. CrossRef
Increased Post-procedural Non-gastrointestinal Adverse Events After Outpatient Colonoscopy in High-risk Patients
David A. Johnson, David Lieberman, John M. Inadomi, Uri Ladabaum, Richard C. Becker, Seth A. Gross, Kristin L. Hood, Susan Kushins, Mark Pochapin, Douglas J. Robertson
Clinical Gastroenterology and Hepatology.2017; 15(6): 883. CrossRef
ADENOMA DETECTION RATE EVALUATION AND QUALITY OF COLONOSCOPY IN THE CENTER-WEST REGION OF BRAZIL
Daniela Medeiros Milhomem CARDOSO, Marco Aurélio Silveira BOTACIN, Marilia Adriano MEKDESSI
Arquivos de Gastroenterologia.2017; 54(4): 315. CrossRef
The Safety of Diagnostic and Therapeutic Colonoscopies in the Very Elderly (≥85 Years of Age)
Rintaro Hashimoto, Masato Nakahori, Tomoki Matsuda
American Journal of Gastroenterology.2016; 111(9): 1366. CrossRef
How Should We Manage Iatrogenic Perforation Caused by Colonoscopy?
Eun Sun Kim
Clinical Endoscopy.2016; 49(3): 214. CrossRef
Is Elderly Age a Simple Predictive Factor for Inadequate Bowel Preparation before Colonoscopy?
Hyun Gun Kim
Gut and Liver.2016; 10(4): 489. CrossRef
Associations Between Parameters of Glucose and Lipid Metabolism and Risk of Colorectal Neoplasm
Yoon Suk Jung, Seungho Ryu, Yoosoo Chang, Kyung Eun Yun, Jung Ho Park, Hong Joo Kim, Yong Kyun Cho, Chong Il Sohn, Woo Kyu Jeon, Byung Ik Kim, Kyuyong Choi, Dong Il Park
Digestive Diseases and Sciences.2015; 60(10): 2996. CrossRef

38,832 View
55 Download
16 Web of Science
15 Crossref

Impact of Sigmoidoscopy and Colonoscopy on Colorectal Cancer Incidence and Mortality: An Evidence-Based Review of Published Prospective and Retrospective Studies: Otto S. Lin, Richard A. Kozarek, Jae Myung Cha; Intest Res 2014;12(4):268-274. Published online October 27, 2014; DOI: https://doi.org/10.5217/ir.2014.12.4.268

Abstract PDF PubReader ePub

Screening for colorectal cancer (CRC) using sigmoidoscopy or colonoscopy is now common in many developed countries. This concise, evidence-based review looks at the impact of sigmoidoscopy or colonoscopy screening on CRC incidence, CRC mortality and overall mortality. Data from controlled retrospective and prospective (observational or randomized) studies have generally shown that sigmoidoscopy and colonoscopy, whether for diagnostic, screening or surveillance purposes, are associated with a significant reduction in CRC incidence and CRC mortality. The data on their impact on overall mortality is much more limited, with most studies unable to report a reduction in overall mortality. The results of three meta-analyses have confirmed these conclusions. As expected, sigmoidoscopy has a predominant effect on left-sided CRC, although some studies have shown modest effects on right-sided colon cancer as well. Most studies on colonoscopy have demonstrated that the protective effect applies to both right and left-sided cancer, although the protection seemed better on the left side. Despite the introduction of other screening and diagnostic modalities for the colon, such as computed tomography colonography and colonic capsule endoscopy, lower endoscopy will continue to be an important mode of screening for CRC and evaluating the colon.

Citations

Citations to this article as recorded by

Risk factors associated with false-positive fecal immunochemical test results in colorectal cancer screening
Iqtida Ahmed Mirza, Fan-Yi Meng, Zhongxue Han, Pei-Zhu Wang, Yue-Yue Li, Yan Zhang, Ming-Jun Ma, Xiu-Li Zuo, Yan-Qing Li, Ru-Chen Zhou
Scientific Reports.2026;[Epub] CrossRef
Cracking the Code of Colorectal Cancer Screening: An Overview With a Focus on Current and Emerging Screening Methods
Hari Prasad Naidu Boyapati, Sidra Tahreem Hashmi Syeda, Arivudainambi Saravanan, Divya Payidiparty, Prasanna Kumar Anbazhagan
Cureus.2025;[Epub] CrossRef
Colorectal cancer screening: A review of current knowledge and progress in research
Sara Ramos Lopes, Claudio Martins, Inês Costa Santos, Madalena Teixeira, Élia Gamito, Ana Luisa Alves
World Journal of Gastrointestinal Oncology.2024; 16(4): 1119. CrossRef
Using of endoscopic polypectomy in patients with diagnosed malignant colorectal polyp – The cross-sectional clinical study
Vladislava Stojic, Natasa Zdravkovic, Tamara Nikolic-Turnic, Nebojsa Zdravkovic, Jelena Dimitrijevic, Aleksandra Misic, Kristijan Jovanovic, Stefan Milojevic, Jelena Zivic
Open Medicine.2023;[Epub] CrossRef
Antihypertensive medications and risk of colorectal cancer in British Columbia
Jia Qi, Parveen Bhatti, John J. Spinelli, Rachel A. Murphy
Frontiers in Pharmacology.2023;[Epub] CrossRef
Unmasking the Silent Threat: Colorectal Cancer’s Alarming Surge in India’s Young Adults
Divya Mahajan
Journal of Surgical Specialties and Rural Practice.2023; 4(3): 111. CrossRef
Risk of post-polypectomy bleeding after endoscopic mucosal resection in patients receiving antiplatelet medication: comparison between the continue and hold groups
Sang Hyun Park, Soo-Kyung Park, Hyo-Joon Yang, Yoon Suk Jung, Jung Ho Park, Chong Il Sohn, Dong Il Park
Surgical Endoscopy.2022; 36(9): 6410. CrossRef
Does Finding Cecal Adenoma Increase the Risk of Discovering More and Advanced Adenomas in the Remainder of the Colon?
Mahum Nadeem, Pratyusha Parava M, Hussein Bitar, Muhammad Hanafi, Sultan Mahmood, Rabia Saleem, Mohammad F. Madhoun
Southern Medical Journal.2022; 115(9): 693. CrossRef
Rising colorectal cancer in young adults
Amol Patel, Vivek Hande
Indian Journal of Cancer.2022; 59(3): 307. CrossRef
Prophylactic clipping after endoscopic mucosal resection of large nonpedunculated colorectal lesions: A meta‐analysis
Tsung‐Chieh Yang, Yi‐Hui Wu, Pei‐Chang Lee, Chung‐Yu Chang, Hsiao‐Sheng Lu, Yu‐Jen Chen, Yi‐Hsiang Huang, Fa‐Yauh Lee, Ming‐Chih Hou
Journal of Gastroenterology and Hepatology.2021; 36(7): 1778. CrossRef
Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines
Tao Zhang, Ling Hu, Jia-Feng Tang, Hang Xu, Kuan Tian, Meng-Na Wu, Shi-Ying Huang, Yu-Mei Du, Peng Zhou, Rui-Jin Lu, Shuang He, Jia-Mei Xu, Jian-Jun Si, Jing Li, Di-Long Chen, Jian-Hua Ran
Molecules.2021; 26(7): 1990. CrossRef
Impact of nonalcoholic fatty liver disease on the risk of metachronous colorectal neoplasia after polypectomy
Nam Hee Kim, Yoon Suk Jung, Jung Ho Park, Dong Il Park, Chong Il Sohn
The Korean Journal of Internal Medicine.2021; 36(3): 557. CrossRef
Biomolecular imaging of colorectal tumor lesions using a FITC-labeled scFv-Cκ fragment antibody
Hyung Il Kim, Jinhyeon Kim, Hyori Kim, Hyeri Lee, Yong Sik Yoon, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Suk-Kyun Yang, Sun Young Kim, Seung-Jae Myung
Scientific Reports.2021;[Epub] CrossRef
Comparison of the Effects of Diltiazem Gel with Lidocaine Gel on Reducing Pain and Discomfort in Patients Undergoing Rectosigmoidoscopy: A Randomized Double-blinded Clinical Trial
Ahmad Hormati, Mohammad Reza Ghadir, Faezeh Alemi, Seyed Saeid Sarkeshikian, Abolfazl Mohammadbeigi, Sajjad Ahmadpour, Seyed Jalal Eshagh-Hoseini
Current Drug Therapy.2021; 16(2): 204. CrossRef
A Comparative Study Evaluating the Incidence of Colorectal Neoplasia(s) in Candidates for Bariatric Surgery by Screening Colonoscopy, 40–49 Versus 50–65 Years Old: a Preliminary Study
Toygar Toydemir, Görkem Özgen, İsmail Çalıkoğlu, Özdal Ersoy, Mehmet Ali Yerdel
Obesity Surgery.2019; 29(8): 2430. CrossRef
Impact of obesity and metabolic abnormalities on the risk of metachronous colorectal neoplasia after polypectomy in men
Nam Hee Kim, Yoon Suk Jung, Jung Ho Park, Dong Il Park, Chong Il Sohn
Journal of Gastroenterology and Hepatology.2019; 34(9): 1504. CrossRef
A Randomized Controlled Trial Comparing Colonoscopic Enema With Additional Oral Preparation as a Salvage for Inadequate Bowel Cleansing Before Colonoscopy
Hyo-Joon Yang, Dong Il Park, Soo-Kyung Park, Sunyong Kim, Taeheon Lee, Yunho Jung, Chang Soo Eun, Dong Soo Han
Journal of Clinical Gastroenterology.2019; 53(8): e308. CrossRef
Improved high-quality colon cleansing with 1L NER1006 versus 2L polyethylene glycol + ascorbate or oral sulfate solution
Alessandro Repici, Emmanuel Coron, Prateek Sharma, Cristiano Spada, Milena Di Leo, Colin L. Noble, Jürgen Gschossmann, Ana Bargalló García, Daniel C. Baumgart
Digestive and Liver Disease.2019; 51(12): 1671. CrossRef
Risk of Developing Metachronous Advanced Colorectal Neoplasia After Polypectomy in Patients With Multiple Diminutive or Small Adenomas
Nam Hee Kim, Yoon Suk Jung, Mi Yeon Lee, Jung Ho Park, Dong Il Park, Chong Il Sohn
American Journal of Gastroenterology.2019; 114(10): 1657. CrossRef
Confounders in Adenoma Detection at Initial Screening Colonoscopy: A Factor in the Assessment of Racial Disparities as a Risk for Colon Cancer
Yakira David, Lorenzo Ottaviano, Jihye Park, Sadat Iqbal, Michelle Likhtshteyn, Samir Kumar, Helen Lyo, Ayanna E. Lewis, Brandon E. Lung, Jesse T. Frye, Li Huang, Ellen Li, Jie Yang, Laura Martello, Shivakumar Vignesh, Joshua D. Miller, Michele Follen, Ev
Journal of Cancer Therapy.2019; 10(04): 269. CrossRef
Right Versus Left Colon Cancer: Resectable and Metastatic Disease
Michele Ghidini, Fausto Petrelli, Gianluca Tomasello
Current Treatment Options in Oncology.2018;[Epub] CrossRef
Risk of developing metachronous advanced colorectal neoplasia after colonoscopic polypectomy in patients aged 30 to 39 and 40 to 49 years
Nam Hee Kim, Yoon Suk Jung, Jung Ho Park, Dong Il Park, Chong Il Sohn
Gastrointestinal Endoscopy.2018; 88(4): 715. CrossRef
The risk of colorectal neoplasia can be different according to the types of family members affected by colorectal cancer
Nam Hee Kim, Hyo‐Joon Yang, Soo‐Kyung Park, Jung Ho Park, Dong Il Park, Chong Il Sohn, Yoon Suk Jung
Journal of Gastroenterology and Hepatology.2018; 33(2): 397. CrossRef
Postoperative adjuvant chemotherapy is associated with a lower incidence of colorectal adenomas in patients with previous colorectal cancer
Hee Seung Lee, Sung Bae Kim, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Won Ho Kim, Tae Il Kim
Gastrointestinal Endoscopy.2018; 87(3): 688. CrossRef
Characteristics of right-sided colonic neoplasia and colonoscopy barriers limiting their early detection and prognosis: a review of the literature
Wolfgang Fischbach, Rory Elsome, Bharat Amlani
Expert Review of Gastroenterology & Hepatology.2018; 12(6): 585. CrossRef
Clinical risk stratification model for advanced colorectal neoplasia in persons with negative fecal immunochemical test results
Yoon Suk Jung, Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Tatsuo Shimosawa
PLOS ONE.2018; 13(1): e0191125. CrossRef
Prospective analysis of delayed colorectal post-polypectomy bleeding
Soo-Kyung Park, Jeong Yeon Seo, Min-Gu Lee, Hyo-Joon Yang, Yoon Suk Jung, Kyu Yong Choi, Hungdai Kim, Hyung Ook Kim, Kyung Uk Jung, Ho-Kyung Chun, Dong Il Park
Surgical Endoscopy.2018; 32(7): 3282. CrossRef
Risk of metachronous neoplasia on surveillance colonoscopy in young patients with colorectal neoplasia
Hyun Gun Kim, Young-Seok Cho, Jae Myung Cha, Jeong Eun Shin, Kyeong Ok Kim, Hyo-Joon Yang, Hoon Sup Koo, Young-Eun Joo, Sun-Jin Boo
Gastrointestinal Endoscopy.2018; 87(3): 666. CrossRef
Risk Factors for False Fecal Immunochemical Test Results in Colorectal Cancer Screening
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
Journal of Clinical Gastroenterology.2017; 51(2): 151. CrossRef
Colonoscopy and Flexible Sigmoidoscopy in Colorectal Cancer Screening and Surveillance
Juliana Yang, John H. Kwon
Current Colorectal Cancer Reports.2017; 13(4): 284. CrossRef
Randomized trial comparing oral sulfate solution with 4‐L polyethylene glycol administered in a split dose as preparation for colonoscopy
Hyo‐Joon Yang, Soo‐Kyung Park, Jee Hyun Kim, Jong Pil Im, Dong Han Yeom, Geom Seog Seo, Dong Il Park
Journal of Gastroenterology and Hepatology.2017; 32(1): 12. CrossRef
Accounting for misclassification in electronic health records-derived exposures using generalized linear finite mixture models
Rebecca A. Hubbard, Eric Johnson, Jessica Chubak, Karen J. Wernli, Aruna Kamineni, Andy Bogart, Carolyn M. Rutter
Health Services and Outcomes Research Methodology.2017; 17(2): 101. CrossRef
Patients' Preferences for Primary Colorectal Cancer Screening: A Survey of the National Colorectal Cancer Screening Program in Korea
Young-Hak Cho, Dae Ho Kim, Jae Myung Cha, Yoon Tae Jeen, Jeong Seop Moon, Jin-Oh Kim, Sang Kil Lee, Yu Kyung Cho, Jong Pil Im, Jae Young Jang, Jeong Eun Shin, Soon Man Yoon, Yunho Jung, Eun Sun Kim, Kang Nyeong Lee, Soo-Jeong Cho, Yeol Kim, Bo Young Park
Gut and Liver.2017; 11(6): 821. CrossRef
External Validation of the Endoscopic Features of Sessile Serrated Adenomas in Expert and Trainee Colonoscopists
Hyo-Joon Yang, Jeong In Lee, Soo-Kyung Park, Yoon Suk Jung, Jin Hee Sohn, Kyu Yong Choi, Dong Il Park
Clinical Endoscopy.2017; 50(3): 279. CrossRef
Clinicopathological Features and Prognostic Factors of Colorectal Neuroendocrine Neoplasms
Mengjie Jiang, Yinuo Tan, Xiaofen Li, Jianfei Fu, Hanguang Hu, Xianyun Ye, Ying Cao, Jinghong Xu, Ying Yuan
Gastroenterology Research and Practice.2017; 2017: 1. CrossRef
Prospective Analysis of Minor Adverse Events After Colon Polypectomy
Soo-Kyung Park, Min-Gu Lee, Seok Hyeon Jeong, Hyo-Joon Yang, Yoon Suk Jung, Kyu Yong Choi, Hungdai Kim, Hyung Ook Kim, Kyung Uk Jeong, Ho-Kyung Chun, Dong Il Park
Digestive Diseases and Sciences.2017; 62(8): 2113. CrossRef
Parameters of Glucose and Lipid Metabolism Affect the Occurrence of Colorectal Adenomas Detected by Surveillance Colonoscopies
Nam Hee Kim, Jung Yul Suh, Jung Ho Park, Dong Il Park, Yong Kyun Cho, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
Yonsei Medical Journal.2017; 58(2): 347. CrossRef
Risk factors of nonadherence to colonoscopy surveillance after polypectomy and its impact on clinical outcomes: a KASID multicenter study
Chung Hyun Tae, Chang Mo Moon, Seong-Eun Kim, Sung-Ae Jung, Chang Soo Eun, Jae Jun Park, Geom Seog Seo, Jae Myung Cha, Sung Chul Park, Jaeyoung Chun, Hyun Jung Lee, Yunho Jung, Jin Oh Kim, Young-Eun Joo, Dong Il Park
Journal of Gastroenterology.2017; 52(7): 809. CrossRef
Association Between Low Relative Muscle Mass and the Risk of Colorectal Neoplasms
Yoon Suk Jung, Nam Hee Kim, Seungho Ryu, Jung Ho Park, Dong Il Park, Chong Il Sohn
Journal of Clinical Gastroenterology.2017; 51(10): e83. CrossRef
Risk factors of missed colorectal lesions after colonoscopy
Jeonghun Lee, Sung Won Park, You Sun Kim, Kyung Jin Lee, Hyun Sung, Pil Hun Song, Won Jae Yoon, Jeong Seop Moon
Medicine.2017; 96(27): e7468. CrossRef
Identifying the optimal strategy for screening of advanced colorectal neoplasia
Yoon Suk Jung, Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn
Journal of Gastroenterology and Hepatology.2017; 32(5): 1003. CrossRef
Molecular Imaging of Colorectal Tumors by Targeting Colon Cancer Secreted Protein-2 (CCSP-2)
Jaeil Kim, Eun-ju Do, Helen Moinova, Sang Mun Bae, Ja Young Kang, Seung-Mo Hong, Stephen P. Fink, Jinmyoung Joo, Young-Ah Suh, Se Jin Jang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Jaewon Choe, Suk-Kyun Yang, Sanfo
Neoplasia.2017; 19(10): 805. CrossRef
Are Hemorrhoids Associated with False-Positive Fecal Immunochemical Test Results?
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
Yonsei Medical Journal.2017; 58(1): 150. CrossRef
Metformin use and the risk of colorectal adenoma: A systematic review and meta‐analysis
Yoon Suk Jung, Chan Hyuk Park, Chang Soo Eun, Dong Il Park, Dong Soo Han
Journal of Gastroenterology and Hepatology.2017; 32(5): 957. CrossRef
Comparison of adenoma detection rate and adenoma per colonoscopy as a quality indicator of colonoscopy
Soo-Kyung Park, Hyun-Young Kim, Chang Kyun Lee, Jae Myung Cha, Chang Soo Eun, Dong Soo Han, Bo-In Lee, Jeong Eun Shin, Dong Il Park
Scandinavian Journal of Gastroenterology.2016; 51(7): 886. CrossRef
Does Polyethylene Glycol (PEG) Plus Ascorbic Acid Induce More Mucosal Injuries than Split-Dose 4-L PEG during Bowel Preparation?
Min Sung Kim, Jongha Park, Jae hyun Park, Hyung Jun Kim, Hyun Jeong Jang, Hee Rin Joo, Ji Yeon Kim, Joon Hyuk Choi, Nae Yun Heo, Seung Ha Park, Tae Oh Kim, Sung Yeon Yang
Gut and Liver.2016; 10(2): 237. CrossRef
Risk of Advanced Colorectal Neoplasia According to the Number of High-Risk Findings at Index Colonoscopy: A Korean Association for the Study of Intestinal Disease (KASID) Study
Yoon Suk Jung, Dong Il Park, Won Hee Kim, Chang Soo Eun, Soo-Kyung Park, Bong Min Ko, Geom Seog Seo, Jae Myung Cha, Jae Jun Park, Kyeong Ok Kim, Chang Mo Moon, Yunho Jung, Eun Soo Kim, Seong Ran Jeon, Chang Kyun Lee
Digestive Diseases and Sciences.2016; 61(6): 1661. CrossRef
A wide variation of the quality of colonoscopy reporting system in the real clinical practice in southeastern area of Korea
Jung Min Lee, Yu Jin Kang, Eun Soo Kim, Yoo Jin Lee, Kyung Sik Park, Kwang Bum Cho, Seong Woo Jeon, Min Kyu Jung, Hyun Seok Lee, Eun Young Kim, Jin Tae Jung, Byung Ik Jang, Kyeong Ok Kim, Yun Jin Chung, Chang Hun Yang
Intestinal Research.2016; 14(4): 351. CrossRef
Metabolic syndrome is a risk factor for adenoma occurrence at surveillance colonoscopy
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
Medicine.2016; 95(32): e4454. CrossRef
Risk Factors Such as Male Sex, Smoking, Metabolic Syndrome, Obesity, and Fatty Liver Do Not Justify Screening Colonoscopies Before Age 45
Yoon Suk Jung, Kyung Eun Yun, Yoosoo Chang, Seungho Ryu, Dong Il Park
Digestive Diseases and Sciences.2016; 61(4): 1021. CrossRef
Comparison of Efficacy of Prophylactic Endoscopic Therapies for Postpolypectomy Bleeding in the Colorectum: A Systematic Review and Network Meta-Analysis
Chan Hyuk Park, Yoon Suk Jung, Eunwoo Nam, Chang Soo Eun, Dong Il Park, Dong Soo Han
American Journal of Gastroenterology.2016; 111(9): 1230. CrossRef
Different risk factors for advanced colorectal neoplasm in young adults
Ji Yeon Kim, Yoon Suk Jung, Jung Ho Park, Hong Joo Kim, Yong Kyun Cho, Chong Il Sohn, Woo Kyu Jeon, Byung Ik Kim, Kyu Yong Choi, Dong Il Park
World Journal of Gastroenterology.2016; 22(13): 3611. CrossRef
Risk of developing advanced colorectal neoplasia after removing high‐risk adenoma detected at index colonoscopy in young patients: A KASID study
Soo‐Kyung Park, Nam Hee Kim, Yoon Suk Jung, Won Hee Kim, Chang Soo Eun, Bong Min Ko, Geom Seog Seo, Jae Myung Cha, Jae Jun Park, Kyeong Ok Kim, Chang Mo Moon, Yoonho Jung, Eun Soo Kim, Seong Ran Jeon, Chang Kyun Lee, Dong Il Park
Journal of Gastroenterology and Hepatology.2016; 31(1): 138. CrossRef
Weight Change and Obesity Are Associated with a Risk of Adenoma Recurrence
Yoon Suk Jung, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi
Digestive Diseases and Sciences.2016; 61(9): 2694. CrossRef
Fecal hemoglobin concentration is useful for risk stratification of advanced colorectal neoplasia
Nam Hee Kim, Min-Jung Kwon, Hyun-young Kim, Taeheon Lee, Seok Hyeon Jeong, Dong Il Park, Kyuyong Choi, Yoon Suk Jung
Digestive and Liver Disease.2016; 48(6): 667. CrossRef
Clinical Characteristics and Mortality of Life-Threatening Events Requiring Cardiopulmonary Resuscitation in Gastrointestinal Endoscopy Units
Hye Min Park, Eun Soo Kim, Sang Min Lee, Yoo Jin Lee, Kyung Sik Park, Kwang Bum Cho, Eun Young Kim, Jin Tae Jung, Kyeong Ok Kim, Byung Ik Jang, Yun Jin Jung, Chang Hun Yang, Hyun Seok Lee, Seong Woo Jeon
Medicine.2015; 94(43): e1934. CrossRef
Developments in Screening Tests and Strategies for Colorectal Cancer
Justin L. Sovich, Zachary Sartor, Subhasis Misra
BioMed Research International.2015; 2015: 1. CrossRef
Race and ethnicity considerations in GI endoscopy
Amy Wang, Aasma Shaukat, Ruben D. Acosta, David H. Bruining, Vinay Chandrasekhara, Krishnavel V. Chathadi, Mohamad A. Eloubeidi, Robert D. Fanelli, Ashley L. Faulx, Lisa Fonkalsrud, Suryakanth R. Gurudu, Loralee R. Kelsey, Mouen A. Khashab, Shivangi Kotha
Gastrointestinal Endoscopy.2015; 82(4): 593. CrossRef

9,067 View
35 Download
63 Web of Science
58 Crossref

Original Article

Association of Gallbladder Polyp with the Risk of Colorectal Adenoma: Jung Won Jeun, Jae Myung Cha, Joung Il Lee, Kwang Ro Joo, Hyun Phil Shin, Jun Uk Lim; Intest Res 2014;12(1):48-52. Published online January 28, 2014; DOI: https://doi.org/10.5217/ir.2014.12.1.48

Abstract PDF PubReader

<b>Background/Aims</b><br/>

Gallbladder polyps and colorectal adenomas share many common risk factors; however, their association has never been studied. The aim of this study was to investigate this association in asymptomatic healthy subjects.

Methods

Consecutive asymptomatic subjects who underwent both screening colonoscopy and abdominal ultrasonography at Kyung Hee University Hospital in Gang Dong between July 2010 and April 2011 were prospectively enrolled. The prevalence of colorectal adenoma was compared between subjects with or without gallbladder polyps. Furthermore, a logistic regression analysis was performed to determine the independent risk factors for colorectal adenoma in these subjects.

Results

Of the 581 participants, 55 presented with gallbladder polyps and 526 did not have gallbladder polyps. Participants with gallbladder polyps showed a trend toward a higher prevalence of colorectal adenoma than those without gallbladder polyps (52.7% vs. 39.2%, P=0.051). Although the result was not statistically significant, gallbladder polyps were found to be a possible risk factor for colorectal adenoma (odds ratio=1.796, 95% confidence interval=0.986-3.269, P=0.055), even after adjusting for potential confounding factors. There was no difference observed in colorectal adenoma characteristics between the two groups.

Conclusions

Our results suggest a possible association between gallbladder polyps and colorectal adenomas. Future studies with larger cohorts are warranted to further investigate this matter.

Citations

Citations to this article as recorded by

Endoscopic characterization and development of a prediction model for colorectal adenomatous polyps
Wen-Cai Luo, Yuan-Fu Yang, Yao Wang, Zhao-Hong Zhang
World Journal of Gastrointestinal Surgery.2026;[Epub] CrossRef
Association between gallbladder disease and colorectal neoplasia: a meta-analysis
Wenbin Geng, Kai Ma, Yizhou Jiang, Shiyu Peng, Xiaoyong Wang
Scientific Reports.2025;[Epub] CrossRef
Metabolic dysfunction-associated steatotic liver disease and gallbladder polyp development: an observational study
Masahiro Sogabe, Toshiya Okahisa, Miwako Kagawa, Takanori Kashihara, Shota Fujmoto, Tomoyuki Kawaguchi, Reiko Yokoyama, Kaizo Kagemoto, Hironori Tanaka, Yoshifumi Kida, Tetsu Tomonari, Yasushi Sato, Masahiko Nakasono, Tetsuji Takayama
Scientific Reports.2024;[Epub] CrossRef
Should Gallbladder Pathologies Be Investigated in Patients With Colon Polyps?
Nihan Turhan, Didem Ertorul, Cengiz Duran, Meryem Gözde Kılıç, Taha Yusuf Kuzan, Servan Yaşar, Dilek Yılmaz, Elbrus Zarbaliyev
Cureus.2024;[Epub] CrossRef
Risk Factors for Colorectal Polyps
嫣琦王
Advances in Clinical Medicine.2023; 13(09): 14803. CrossRef
Research Progress of Factors Related to CRP in Middle-Aged and Elderly People
瑞武邢
Advances in Clinical Medicine.2022; 12(11): 10466. CrossRef
Association of gallbladder diseases with risk of gastrointestinal polyps
Wenbin Geng, Xiangrong Qin, Peng Yang, Junmei Wang, Jing Yu, Xiaoyong Wang
BMC Gastroenterology.2022;[Epub] CrossRef
Gallbladder Polyps Are Associated with Proximal Colon Polyps
Kuan-Chieh Lee, Wen-Juei Jeng, Chen-Ming Hsu, Chia-Jung Kuo, Ming-Yao Su, Cheng-Tang Chiu
Gastroenterology Research and Practice.2019; 2019: 1. CrossRef
Gallbladder Adenoumatous Polyps prevelance in Cholcystectomy in Saudi Arabia-cross sectional study
Alharbi Mohammad
Journal of Surgery and Surgical Research.2019; 5(1): 047. CrossRef
Gallbladder stones and gallbladder polyps associated with increased risk of colorectal adenoma in men
Yen‐Ling Liu, Jin‐Shang Wu, Yi‐Ching Yang, Feng‐Hwa Lu, Chih‐Ting Lee, Wan‐Ju Lin, Chih‐Jen Chang
Journal of Gastroenterology and Hepatology.2018; 33(4): 800. CrossRef
Risk of Colorectal Neoplasia According to Fatty Liver Severity and Presence of Gall Bladder Polyps
Taeyoung Lee, Kyung Eun Yun, Yoosoo Chang, Seungho Ryu, Dong Il Park, Kyuyong Choi, Yoon Suk Jung
Digestive Diseases and Sciences.2016; 61(1): 317. CrossRef
Can gallbladder polyps predict colorectal adenoma or even neoplasia? A systematic review
Konstantinos Stergios, Christos Damaskos, Maximos Frountzas, Nikolaos Nikiteas, Olutunde Lalude
International Journal of Surgery.2016; 33: 23. CrossRef
The Risk of Colorectal Neoplasia in Patients with Gallbladder Diseases
Sung Noh Hong, Tae Yoon Lee, Sung-Cheol Yun
Journal of Korean Medical Science.2015; 30(9): 1288. CrossRef
Recent Updates on the Diagnosis and Management of Gallbladder Polyps
Eaum Seok Lee
Korean Journal of Pancreas and Biliary Tract.2014; 19(2): 64. CrossRef

7,569 View
49 Download
9 Web of Science
14 Crossref

First
Prev
Page of 1
Next
Last

Search