| Comparative Value of Colonic Tissue Culture and Stool Culture for Diagnosis of Acute Infectious Colitis |
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Chang Soo Eun, Dong Soo Han, Jong Pyo Kim, Hang Lak Lee, Jin Bae Kim, Joon Yong Park, Yong Chul Jeon, Joo Hyun Sohn, Joon Soo Hahm |
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Department of Internal Medicine, Hanyang University College of Medicine, Kuri, Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea
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| 급성 감염성 대장염의 진단에 있어서 대장점막조직 배양검사와 분변 배양검사의 비교연구 |
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은창수, 한동수, 김종표, 이항락, 김진배, 박준용, 전용철, 손주현, 함준수 |
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한양대학교 의과대학 내과학교실, 한림대학교 의과대학 내과학교실 |
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| Abstract |
Background/Aims
Although the diagnosis of acute infectious diarrhea can be easily suggested by clinical features, identification of the causative organism is mandatory for both accurate diagnoses and epidemiological investigations. The aim of this study was to compare the accuracy of culture of biopsy specimens obtained during colonoscopy with that of stool culture in acute infectious colitis. Methods: From March 1996 to July 2001, forty-five patients who were suspected of having acute infectious colitis were enrolled. In all patients, fecal specimens and colonic tissues excised during colonoscopy were both obtained and then cultured. Results: In stool examinations, WBC and occult blood were positive in 15 (33.3%) and 14 (31.1%) cases, respectively. In culture study, some causative microorganisms were identified in 18 (40%) of the 45 cases investigated. Most common pathogen was Salmonella species (12 cases). Whereas culture of the colonic tissue biopsy specimens was positive for bacteria in 10 of 45 cases (22.2%), stool culture revealed pathogen in 13 of 45 cases (28.9%). In 5 cases, both stool and colonic tissue biopsy specimens were positive for bacteria. Conclusions: Our findings suggest that both colonic tissue culture and stool culture may have a complementary role in diagnosis of acute infectious colitis. (Intestinal Research 2004;2:83-88) |
| Key Words:
Acute infectious colitis, Colonic tissue culture, Stool culture |
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