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- Original Article Comparative Value of Colonic Tissue Culture and Stool Culture for Diagnosis of Acute Infectious Colitis
- Chang Soo Eun, Dong Soo Han, Jong Pyo Kim, Hang Lak Lee, Jin Bae Kim, Joon Yong Park, Yong Chul Jeon, Joo Hyun Sohn, Joon Soo Hahm
- Intestinal Research 2004;2(2):83-88. Published online: December 22, 2004
Department of Internal Medicine, Hanyang University College of Medicine, Kuri, Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea
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Abstract
Background/Aims
Although the diagnosis of acute infectious diarrhea can be easily suggested by clinical features, identification of the causative organism is mandatory for both accurate diagnoses and epidemiological investigations. The aim of this study was to compare the accuracy of culture of biopsy specimens obtained during colonoscopy with that of stool culture in acute infectious colitis. Methods: From March 1996 to July 2001, forty-five patients who were suspected of having acute infectious colitis were enrolled. In all patients, fecal specimens and colonic tissues excised during colonoscopy were both obtained and then cultured. Results: In stool examinations, WBC and occult blood were positive in 15 (33.3%) and 14 (31.1%) cases, respectively. In culture study, some causative microorganisms were identified in 18 (40%) of the 45 cases investigated. Most common pathogen was Salmonella species (12 cases). Whereas culture of the colonic tissue biopsy specimens was positive for bacteria in 10 of 45 cases (22.2%), stool culture revealed pathogen in 13 of 45 cases (28.9%). In 5 cases, both stool and colonic tissue biopsy specimens were positive for bacteria. Conclusions: Our findings suggest that both colonic tissue culture and stool culture may have a complementary role in diagnosis of acute infectious colitis. (Intestinal Research 2004;2:83-88)
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