| A Case of Rifampin-induced Severe Thrombocytopenia and Leukopenia in a Patient with Intestinal Tuberculosis |
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Ji Woong Kim, Gum Mo Jung, Eun Young Cho, Chang Soo Choi, Geom Seog Seo, Jin Woong Cho, Suck Chei Choi, Yong Ho Nah |
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Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Department of Internal Medicine, Presbterian Medical Center, Jeonju, Korea
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| 장결핵 치료 중 Rifampin으로 유도된 심한 혈소판 감소증 및 백혈구 감소증 1예 |
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김지웅, 정금모, 조은영, 최창수, 서검석, 조진웅, 최석채, 나용호 |
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원광대학교 의과대학 내과학교실, 예수병원 내과 |
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| Abstract |
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Drug induced thrombocytopenia is a relatively not uncommon and potentially serious side effect of therapy. It's characterized by thrombocytopenia, petechia, purpuric lesions and occasionally serious bleeding such as intracranial hemorrhage. The patient was 24 year-old female who was given rifampin 600mg daily for treatment of intestinal tuberculosis. Rifampin-induced immune thrombocytopenia was occurred 25 days after initiating therapy. Platelet and leukocyte count were 23,000/mm3, 2,850/mm3, respectively. Two week after discontinuation of antituberculous medication, platelet count was recovered. We report this case with a review of literature. (Intestinal Research 2006;4:64-68) |
| Key Words:
Rifampin, Thrombocytopenia, Leukopenia |
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