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- Case Report A Case of Rifampin-induced Severe Thrombocytopenia and Leukopenia in a Patient with Intestinal Tuberculosis
- Ji Woong Kim, Gum Mo Jung, Eun Young Cho, Chang Soo Choi, Geom Seog Seo, Jin Woong Cho, Suck Chei Choi, Yong Ho Nah
- Intestinal Research 2006;4(1):64-68. Published online: June 30, 2006
Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Department of Internal Medicine, Presbterian Medical Center, Jeonju, Korea
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Abstract
Drug induced thrombocytopenia is a relatively not uncommon and potentially serious side effect of therapy. It's characterized by thrombocytopenia, petechia, purpuric lesions and occasionally serious bleeding such as intracranial hemorrhage. The patient was 24 year-old female who was given rifampin 600mg daily for treatment of intestinal tuberculosis. Rifampin-induced immune thrombocytopenia was occurred 25 days after initiating therapy. Platelet and leukocyte count were 23,000/mm3, 2,850/mm3, respectively. Two week after discontinuation of antituberculous medication, platelet count was recovered. We report this case with a review of literature. (Intestinal Research 2006;4:64-68)
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