A Case of Gastrointestinal Amyloidosis in Asymptomatic Multiple Myeloma |
Sae Hee Kim, Yun Jung Lee, Sung Hee Jung, Woo Jin Hyeon, Hyang Ie Lee, Hyeon Woong Yang, Anna Kim, Sang Woo Cha, Dong Wook Kang |
Departments of Internal Medicine and Pathology, Eulji University College of Medicine, Eulji University Hospital, Daejeon, Korea
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무증상 다발성 골수종(Asymptomatic Multiple Myeloma)에서 발생한 위장관 아밀로이드증 1예 |
김새희, 이윤정, 정성희, 현우진, 이향이, 양현웅, 김안나, 차상우, 강동욱 |
을지대학교 의과대학 을지대학병원 내과학교실, 병리학교실 |
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Abstract |
Amyloidosis is a disorder characterized by extracellular deposition of amyloid materials in multiple organs and tissues. Amyloidosis commonly shows a systemic involvement. Gastrointestinal involvement is common in amyloidosis and is usually asymptomatic. The gastrointestinal manifestations include gastroparesis, diarrhea, steatorrhea, constipation, intestinal pseudo-obstruction, and bleeding. The diagnosis of amyloidosis is difficult because there are absence of systemic symptoms and nonspecific endoscopic findings. Asymptomatic multiple myeloma is an asymptomatic plasma-cell proliferative disorder associated with a high risk of progression to symptomatic multiple myeloma or amyloidosis. Recently, we experienced a 60-year-old man who presented with hematochezia and weight loss as manifestations of gastrointestinal amyloidosis involving the stomach and the colon induced in asymptomatic multiple myeloma confirmed by endoscopic biopsies and bone marrow biopsy. We report a case with a review of the literature. (Intest Res 2009;7:123-128) |
Key Words:
Amyloidosis, Multiple Myeloma, Stomach, Colon |
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