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Intest Res > Volume 9(2); 2011 > Article
Intestinal Research 2011;9(2):97-104.
DOI:    Published online August 30, 2011.
The Clinical Utility of Positron Emission Tomography-computed Tomography in the Evaluation of Inflammatory Bowel Diseases
Sung Ho Ryu, Jae Hee Cheon, Won Jun Kang, Jin Young Kim, Bo Kyung Kim, Jin Young Yoon, Yoon Suk Jung, Hyun Mi Heo, Jin Ha Lee, Soung Min Jeon, Sung Pil Hong, Tae Il Kim, Won Ho Kim
Department of Internal Medicine and Institute of Gastroenterology, Division of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seoul, Korea
염증성 장질환 진단에 있어서 Positron Emission Tomography-computed Tomography의 임상적 유용성
류성호, 천재희, 강원준, 김진영, 김보경, 윤진영, 정윤숙, 허현미, 이진하, 전승민, 홍성필, 김태일, 김원호
연세대학교 의과대학 내과학교실, 소화기병 연구소, 핵의학과
Positron emission tomography-computed tomography (PET-CT) is a nuclear imaging technique that provides noninvasive, three dimensional, quantitative images. Recently, PET-CT has been shown to be valuable in assessing patients with inflammatory diseases; however, the clinical utility of PET-CT in the evaluation of inflammatory bowel disease (IBD) has not been defined. Thus, the aim of this study was to determine the clinical utility of PET-CT in the evaluation of IBD. Methods: Between November 2006 and September 2010, clinical, endoscopic, and radiological data on 14 patients (6 males and 8 females: age range, 33-79 years) with suspected IBD were collected. The standard work-up method for a definite diagnosis of IBD included ileocolonoscopy. Results: The 14 patients were divided into the following five groups: ulcerative colitis (n=4, 29%), intestinal Behcet's disease (n=3, 21%), intestinal tuberculosis (n=2, 14%), malignancy (n=2, 14%), and no abnormal findings with colonoscopy (n=3, 21%). A PET-CT based-diagnosis of IBD correlated with a colonoscopic diagnosis in nine cases (64.3%), but the matching ratio of the distribution of lesions between PET-CT findings and colonoscopic findings was only 18.1% (2/11). Conclusions: The utility of PET-CT in the diagnosis of IBD requires further evaluation. (Intest Res 2011;9:97-104)
Key Words: Inflammatory Bowel Disease, PET-CT, Clinical Utility
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