Endoscopic and radiologic studies are frequently required in inflammatory bowel disease to determine disease activity, extent of disease, and delineating type. Positron emission tomography (PET) using fluorine-18-fluoro-deoxyglucose to identify metabolically active tissues may offer a simple noninvasive alternative to conventional studies in identification and localization of active intestinal inflammation with inflammatory bowel disease. Crohn's disease can also be detected by PET-CT. In this case, we discribe a small bowel Crohn's disease with PET-CT finding. There was intensely increased fluorine-18-fluoro-deoxyglucose uptake in terminal ileum area. (Intestinal Research 2006;4:57-60)