| A Case of Cronkhite-Canada Syndrome Presenting with Hematochezia |
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Hyun Ji Lee, Sang Jung Park, Hyuk Soon Choi, Bora Keum, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu |
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Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
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| 혈변으로 내원하여 발견된 Cronkhite-Canada Syndrome 증례 1예 |
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이현지, 박상정, 최혁순, 금보라, 서연석, 김용식, 진윤태, 이홍식, 전훈재, 엄순호, 김창덕, 류호상 |
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고려대학교 의과대학 내과학교실 |
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| Abstract |
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Cronkhite-Canada syndrome (CCS) is a rare, non-familial hamartomatous polyposis syndrome characterized by multiple polyps in the entire gastrointestinal tract, nail dystrophy, skin pigmentation, and systemic alopecia. The clinical symptoms of this syndrome include diarrhea, abdominal pain, and alopecia often accompanied by taste disturbances, hypoalbuminemia, recurrent infections, nutritional absorption disturbances, heart failure, and gastrointestinal bleeding. We report a patient with CCS who was admitted complaining of hematochezia, melena, and a 1 month history of diarrhea, nail changes, taste disturbances, and alopecia. Upper endoscopy, colonoscopy, and capsule endoscopy were performed and showed numerous polyps in the stomach, small intestine, and large intestine. Histological sections of these polyps showed edematous stroma and cystically dilated foveolar epithelium, which was consistent with CCS. We diagnosed CCS based on the clinical symptoms and the histological findings of the polyps found via endoscopy. We report on this case and review this syndrome. (Intest Res 2011;9:238-242) |
| Key Words:
Intestinal Polyposis, Capsule Endoscopy, Gastrointestinal Hemorrhage, Melena |
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